Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 1444301..1444838 Replicon chromosome
Accession NZ_CP084222
Organism Arsenophonus apicola strain ArsBeeUS

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LDL57_RS06865 Protein ID WP_180560064.1
Coordinates 1444545..1444838 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LDL57_RS06860 Protein ID WP_180560065.1
Coordinates 1444301..1444555 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LDL57_RS06835 (LDL57_06835) 1439458..1439748 + 291 WP_180558906.1 type II toxin-antitoxin system HicA family toxin -
LDL57_RS06840 (LDL57_06840) 1439893..1442778 + 2886 WP_225507356.1 phage tail tape measure protein -
LDL57_RS06845 (LDL57_06845) 1442882..1443394 + 513 WP_180560068.1 zinc ribbon domain-containing protein -
LDL57_RS06850 (LDL57_06850) 1443519..1443830 + 312 WP_180560067.1 type II toxin-antitoxin system RelE/ParE family toxin -
LDL57_RS06855 (LDL57_06855) 1443833..1444123 + 291 WP_180560066.1 NadS family protein -
LDL57_RS06860 (LDL57_06860) 1444301..1444555 + 255 WP_180560065.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LDL57_RS06865 (LDL57_06865) 1444545..1444838 + 294 WP_180560064.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LDL57_RS06870 (LDL57_06870) 1445077..1445424 + 348 WP_225507358.1 phage tail protein -
LDL57_RS06875 (LDL57_06875) 1445421..1446164 + 744 WP_180560063.1 phage minor tail protein L -
LDL57_RS06880 (LDL57_06880) 1446161..1446874 + 714 WP_180560062.1 C40 family peptidase -
LDL57_RS06885 (LDL57_06885) 1446871..1447467 + 597 WP_180560061.1 tail assembly protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1419238..1471118 51880


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-56)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11484.43 Da        Isoelectric Point: 10.2491

>T218327 WP_180560064.1 NZ_CP084222:1444545-1444838 [Arsenophonus apicola]
MKFSIEFDERALKEWQKLDINIREQFKKKLRKLQDNPYIESARLHGELAGCFKIKLHSSGYRLVYQVIDEEIVIWVIAIA
KREKSTVYKSATGRIAR

Download         Length: 294 bp

>T218327 NZ_CP115837:323117-323485 [Klebsiella pneumoniae]
ATGACGCTGCAGATTATCTCAGCGGAAGAGATAATACAGTTTCACGACAGGCTGCTCCGCGTCACGCCTGGCGTTGCCGG
TATGCCCGATCCGGGGCGTGCCGAAGCGATAATGTATAGGGTGCTAAACAAAATTGAATATGAAGGTGTGACAGACGTGT
GGCGACTCGCTGCGATGCATCTGCTGGCGATTTCTCGCGGTCATATATTTAATGATGGTATTAAGCGTACGGCACTGTTT
ATCACCCTGCTTTTTTTAAAGCGAAATGGAATTATATTGCCAGCGAATCCAGACTTCGTCGGCATGACCGTCGAGGCAGC
AGCAGGGCAACTTACCCTGGAACAGATTGTCGCGCGTTTGCGCGGATGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9937.43 Da        Isoelectric Point: 4.9008

>AT218327 WP_180560065.1 NZ_CP084222:1444301-1444555 [Arsenophonus apicola]
MSTIQIRVDEELKKNAYRAFDKMNLSPSDAMRLFLRYVVENEKLPFTEVSVLIAEQDDDNDILEVVRERLKKPARRVRVN
LDEI

Download         Length: 255 bp

>AT218327 NZ_CP115837:322899-323120 [Klebsiella pneumoniae]
ATGAGAACGGTTAACTATAGCGAAGCCCGGCAAAATCTGGCCGATGTGCTGGAAAGCGCAGTGACAGGTGTACCTGTGAC
CATTACCCGTCGTGGGCATAAATCTGCAGTCATCATTAGTGCAGAAGAGTTTGAACGCTACCAGGCGGCCAGAATGGATG
ATGAGTTCGCGGCTATCATGGCGGTTCATGGTGATGAGATCAGGGAGCTTGCGGATAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References