Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 17258..17735 Replicon plasmid p1
Accession NZ_CP084213
Organism Pseudomonas amygdali strain 35-1

Toxin (Protein)


Gene name pasB Uniprot ID A0A0P9I0A0
Locus tag LCH33_RS28740 Protein ID WP_005730593.1
Coordinates 17469..17735 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID A0A3R8W5Z2
Locus tag LCH33_RS28735 Protein ID WP_005730594.1
Coordinates 17258..17485 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LCH33_RS28700 (LCH33_005714) 12962..13357 + 396 WP_102886351.1 hypothetical protein -
LCH33_RS28705 (LCH33_005715) 13379..13939 + 561 WP_180988335.1 single-stranded DNA-binding protein -
LCH33_RS28710 (LCH33_005716) 14130..14957 + 828 WP_102886353.1 DUF932 domain-containing protein -
LCH33_RS28715 (LCH33_005717) 15016..15438 + 423 WP_102886354.1 hypothetical protein -
LCH33_RS28720 (LCH33_005718) 15471..15776 + 306 WP_225231715.1 TrfB-related DNA-binding protein -
LCH33_RS28725 (LCH33_005719) 15798..16082 + 285 WP_102886355.1 hypothetical protein -
LCH33_RS28730 (LCH33_005720) 16195..16797 + 603 WP_102886356.1 hypothetical protein -
LCH33_RS28735 (LCH33_005721) 17258..17485 + 228 WP_005730594.1 hypothetical protein Antitoxin
LCH33_RS28740 (LCH33_005722) 17469..17735 + 267 WP_005730593.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LCH33_RS28745 (LCH33_005723) 17858..19135 - 1278 WP_225231716.1 LLM class flavin-dependent oxidoreductase -
LCH33_RS28750 (LCH33_005724) 19169..19933 - 765 WP_102886303.1 ABC transporter ATP-binding protein -
LCH33_RS28755 (LCH33_005725) 19958..20746 - 789 WP_102886304.1 ABC transporter permease -
LCH33_RS28760 (LCH33_005726) 20743..21648 - 906 WP_102886305.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid aph(6)-Id / aph(3'')-Ib - 1..76741 76741


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-87)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10201.73 Da        Isoelectric Point: 10.2748

>T218304 WP_005730593.1 NZ_CP084213:17469-17735 [Pseudomonas amygdali]
MAWTIDYTDTAKTQLRKLDKQSAKRILDFMDERVSSRDDPRTTGKALTGPLGGLWRYRVGDFRVICEIQDGALRILVVQL
GNRREVYR

Download         Length: 267 bp

>T218304 NZ_CP115820:1805609-1805902 [Pseudomonas tohonis]
ATGATGGAAGAGCTGTACGGCTACGATCCGGCCGAAGCGCTGGGCAGCCCGGAGGCCATTGCAGTATTCGTGGCCGATGC
GTTGGAGACCGGCGATGCGGCTTATATCGCCAAGGCGATGGGAGTGGTCGCTCGGGCGAAGGGGATGACCGAGCTGGCGC
GGGAGACCGGTCTGTCCCGGGAGCAGCTGTATCGTTCTTTCAGCGACCAGGGGAACCCGACCCTACGGACCATGCTCGCC
GTCATGCGTGCCCTTGGGCTGGACATGACTGCCAAGCCCCACAGTGCCGCCTGA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8540.57 Da        Isoelectric Point: 4.6135

>AT218304 WP_005730594.1 NZ_CP084213:17258-17485 [Pseudomonas amygdali]
MATSIRLAPETEQRLDFLATSTGRTKAYYLREIIDHGLTDLEDYYLAAEVLERVRKNTEVVHSAADVRKDLGLDD

Download         Length: 228 bp

>AT218304 NZ_CP115820:1805313-1805612 [Pseudomonas tohonis]
ATGATTACCATCAGGCAGACCGCGACCTTCGCGGCCTGGGAGCGGAAGCTCAAGGACCGCAAAGCCCGAGCAGCCATTGC
CGCACGCATCTTCCGGCTGGCCAATGGCCTCCCCGGGGATGTCGCTCCGGTAGGGCAGGGCGTGAGCGAGATGCGGATTA
ATTACGGCCCCGGCTACCGCGTCTATTTCCAGCAGCGGGGCAATGAACTGGTGATCCTGCTCTGTGGCGGAGACAAATCC
AGCCAGGGCCGGGACATCGAGCAGGCCAGGCGCCTGGCGGCTGAGTGGAGGTCGCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0P9I0A0

Antitoxin

Source ID Structure
AlphaFold DB A0A3R8W5Z2

References