Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/RelE-RHH |
| Location | 1952240..1952753 | Replicon | chromosome |
| Accession | NZ_CP084212 | ||
| Organism | Pseudomonas amygdali strain 35-1 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | LCH33_RS08755 | Protein ID | WP_057405131.1 |
| Coordinates | 1952240..1952524 (-) | Length | 95 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | Q48KT0 |
| Locus tag | LCH33_RS08760 | Protein ID | WP_011168200.1 |
| Coordinates | 1952514..1952753 (-) | Length | 80 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LCH33_RS08740 (LCH33_001738) | 1948383..1950311 | + | 1929 | WP_010198401.1 | methyl-accepting chemotaxis protein | - |
| LCH33_RS08745 (LCH33_001739) | 1950342..1951274 | - | 933 | WP_057405133.1 | DMT family transporter | - |
| LCH33_RS08750 (LCH33_001740) | 1951349..1952203 | + | 855 | WP_057405132.1 | LysR family transcriptional regulator | - |
| LCH33_RS08755 (LCH33_001741) | 1952240..1952524 | - | 285 | WP_057405131.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| LCH33_RS08760 (LCH33_001742) | 1952514..1952753 | - | 240 | WP_011168200.1 | CopG family ribbon-helix-helix protein | Antitoxin |
| LCH33_RS08765 (LCH33_001743) | 1952913..1953929 | - | 1017 | WP_011168201.1 | 1-aminocyclopropane-1-carboxylate deaminase | - |
| LCH33_RS08770 (LCH33_001744) | 1954116..1954622 | + | 507 | WP_057405136.1 | Lrp/AsnC family transcriptional regulator | - |
| LCH33_RS08775 (LCH33_001745) | 1954772..1955680 | + | 909 | WP_005744311.1 | DUF808 domain-containing protein | - |
| LCH33_RS08780 (LCH33_001746) | 1955859..1956644 | - | 786 | WP_002552796.1 | outer membrane protein OmpK | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 95 a.a. Molecular weight: 10617.29 Da Isoelectric Point: 10.4249
>T218300 WP_057405131.1 NZ_CP084212:c1952524-1952240 [Pseudomonas amygdali]
MQVEWLKTALKNLDEEAAYIAQDNPAAAAAFVKAIQSSVTQLASFPAMGREGRIAGAREWPLPDLPYLIPYRIRSGRLQV
LRIFHTRRQSPPVW
MQVEWLKTALKNLDEEAAYIAQDNPAAAAAFVKAIQSSVTQLASFPAMGREGRIAGAREWPLPDLPYLIPYRIRSGRLQV
LRIFHTRRQSPPVW
Download Length: 285 bp
>T218300 NZ_CP115817:c3258973-3258404 [Pseudomonas mendocina]
ATGTTCAAGCCGCAGCTGGTGACCTTGCAACGTGGCGCTTTGCGCCTGGAACCGCTTTCCGATACGGATATTCCGGCGCT
GGTGGCATTGGCCGAGACCAATCGCGAAGAGCTGCTGTACATGAGCGGCACCCAGCGTCTGGACTGGTATCGCAGTGCCC
TGACCGATCTGCGCGAGCAACGCGCGTTGCCGTTCGTCATTCGTCTGGGCGACGAGCTGGTGGGTACCACGCGTTTCGCC
GATTTCATGAATACCCTGCCGGCCTGCGAAATCGGCTGGACCTGGATCGACCGCAATCAGCATGGCAGCGGCCTGAATAC
CACCATCAAGTACCTGATGCTCAAGCATGCCTTCGATAACTGGGGCATGGTCCGGGTGCAGTTGAAAACGGCGGCCAGCA
ACCTGCGCTCGCAACGCGCCATCGAGAAGCTGGGTGCCGTGCGTGAGGGGCGGTTGCGCAATCACCGCCGGTTGGCCGAT
GGCCGCCTCGACGATACCGTGCTGTACAGCATCACCGACCAGGAGTGGCCGGCGCTGCGAGAAAACATGGAGTCGGGCTT
CGGCGCCTGA
ATGTTCAAGCCGCAGCTGGTGACCTTGCAACGTGGCGCTTTGCGCCTGGAACCGCTTTCCGATACGGATATTCCGGCGCT
GGTGGCATTGGCCGAGACCAATCGCGAAGAGCTGCTGTACATGAGCGGCACCCAGCGTCTGGACTGGTATCGCAGTGCCC
TGACCGATCTGCGCGAGCAACGCGCGTTGCCGTTCGTCATTCGTCTGGGCGACGAGCTGGTGGGTACCACGCGTTTCGCC
GATTTCATGAATACCCTGCCGGCCTGCGAAATCGGCTGGACCTGGATCGACCGCAATCAGCATGGCAGCGGCCTGAATAC
CACCATCAAGTACCTGATGCTCAAGCATGCCTTCGATAACTGGGGCATGGTCCGGGTGCAGTTGAAAACGGCGGCCAGCA
ACCTGCGCTCGCAACGCGCCATCGAGAAGCTGGGTGCCGTGCGTGAGGGGCGGTTGCGCAATCACCGCCGGTTGGCCGAT
GGCCGCCTCGACGATACCGTGCTGTACAGCATCACCGACCAGGAGTGGCCGGCGCTGCGAGAAAACATGGAGTCGGGCTT
CGGCGCCTGA
Antitoxin
Download Length: 80 a.a. Molecular weight: 8688.78 Da Isoelectric Point: 4.4354
>AT218300 WP_011168200.1 NZ_CP084212:c1952753-1952514 [Pseudomonas amygdali]
MSTMSLRLPDEMADTLAHLAKATGRSKSFLALDALREYLTREAWQIAEIQRAIEEADAGEFASTEDVKAVMDKWSGNAG
MSTMSLRLPDEMADTLAHLAKATGRSKSFLALDALREYLTREAWQIAEIQRAIEEADAGEFASTEDVKAVMDKWSGNAG
Download Length: 240 bp
>AT218300 NZ_CP115817:c3258398-3257571 [Pseudomonas mendocina]
ATGCAGAGCCGCGAGCAGACCCGCTTCTGGCAAGCCTCCGCATTGAGCGGAGTCGAGCTGCTGCAGGCGCGCTATCTGGA
GCAACGTTTTGCACCTCACGTGCACGAGGGCTTCGTTTTTACCGTGATCGAGCACGGCGCCCAGCGCTTTCGCCATCGCG
GCAGCGATCATTTGGCTCCGCAGGGCAGCATGGTGCTGATCAATCCGGATGAGGTGCACACAGGCTCCAAGGCGCATGAG
GATGGCTGGCGCTATCGCGGCTTCTATCCCGGCAACGCCCAGGTGCTGGGGGCGCTGCAGGAGCTGGGGCTGGCCAAGTC
GGGCATGCCGTCGTTTCCCTTCAGCGTGCTGCATGATCCGCAGTTGCACAGCGCCTTCCTGCAACTGCACCGACTGCTTG
ATGACGGTGCCGAGGCGCTGCAGCAGCAACTGGCCTGGCGTGAGGCGATTCTGTTGTTGTTCCAGCGTCACGCGCGGCTT
GCCGAGCCCCGCGCTCCCGGGCGTGAGCCCTGGGCCGTGGCCTGCGCCAAGCAGATGCTCGCCGAGCGGCTGATCGAGCC
GCCGACCCTGGAAGAGCTGGCTGCCGCGGTCAACCTCTCACCCTTTCATTTCGCCCGCGTATTTCGCCGTGCGACCGGGT
TGCCGCCGCATGCCTGGCTCAAGCAGCGTCGTCTGGAACAGGCGCGGGCATTGCTCAAGACAGGCTGCACGGCGGTCACC
GCGGCCACGCAGCTGGGCTTTGCCGATCAGAGTCACCTGTCGCGGCAGTTCAAGCAGGCCTATGGCGTCAGCCCTGGCGA
GTATCGCAACGCCGTGGCTCGCAGCTGA
ATGCAGAGCCGCGAGCAGACCCGCTTCTGGCAAGCCTCCGCATTGAGCGGAGTCGAGCTGCTGCAGGCGCGCTATCTGGA
GCAACGTTTTGCACCTCACGTGCACGAGGGCTTCGTTTTTACCGTGATCGAGCACGGCGCCCAGCGCTTTCGCCATCGCG
GCAGCGATCATTTGGCTCCGCAGGGCAGCATGGTGCTGATCAATCCGGATGAGGTGCACACAGGCTCCAAGGCGCATGAG
GATGGCTGGCGCTATCGCGGCTTCTATCCCGGCAACGCCCAGGTGCTGGGGGCGCTGCAGGAGCTGGGGCTGGCCAAGTC
GGGCATGCCGTCGTTTCCCTTCAGCGTGCTGCATGATCCGCAGTTGCACAGCGCCTTCCTGCAACTGCACCGACTGCTTG
ATGACGGTGCCGAGGCGCTGCAGCAGCAACTGGCCTGGCGTGAGGCGATTCTGTTGTTGTTCCAGCGTCACGCGCGGCTT
GCCGAGCCCCGCGCTCCCGGGCGTGAGCCCTGGGCCGTGGCCTGCGCCAAGCAGATGCTCGCCGAGCGGCTGATCGAGCC
GCCGACCCTGGAAGAGCTGGCTGCCGCGGTCAACCTCTCACCCTTTCATTTCGCCCGCGTATTTCGCCGTGCGACCGGGT
TGCCGCCGCATGCCTGGCTCAAGCAGCGTCGTCTGGAACAGGCGCGGGCATTGCTCAAGACAGGCTGCACGGCGGTCACC
GCGGCCACGCAGCTGGGCTTTGCCGATCAGAGTCACCTGTCGCGGCAGTTCAAGCAGGCCTATGGCGTCAGCCCTGGCGA
GTATCGCAACGCCGTGGCTCGCAGCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|