Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 4034634..4035229 Replicon chromosome
Accession NZ_CP084209
Organism Escherichia coli strain EC2648-R2

Toxin (Protein)


Gene name chpB Uniprot ID U9XNP6
Locus tag LDB16_RS19685 Protein ID WP_000239577.1
Coordinates 4034634..4034984 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID U9Y2K1
Locus tag LDB16_RS19690 Protein ID WP_001223208.1
Coordinates 4034978..4035229 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-114)

Antitoxin

SpoVT-AbrB domain

(6-49)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12492.40 Da        Isoelectric Point: 5.5572

>T218296 WP_000239577.1 NZ_CP084209:c4034984-4034634 [Escherichia coli]
MVKKSEFERGDIVLVGFDPASGHEQQGAGRPALVLSVQAFNQLGMTLVAPITQGGNFARYAGFSVPLHCEEGDVHGVVLV
NQVRMMDLHARLAKRIGLAADEVVEEALLRLQAVVE

Download         Length: 351 bp

>T218296 NZ_CP115784:c181131-180841 [Paracoccus aerodenitrificans]
ATGACGTCATCCTATTTGCTTACGCCACTGGCGGAAACGGATCTCGAAGAGATCTGGCTTTACACAGCACGTCGCTGGTC
GCCAGAGCAAGCCGAGATTTACACCAATGACATCATTGATGCATGCGAGGATCTCGTAAGCGGAAGGAAGTCAGGGCGCC
CGGTTGCCATTCGTGACGGATATTTCAAAACAATGGCAGGCCGACACATCATCTACTTCCAGCGCAGGGCAGAAACTCTG
CTAGTCGTCCGCATTCTTCACCAGAGAATGGACATCAAGAGTCACCTATAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9271.58 Da        Isoelectric Point: 4.4201

>AT218296 WP_001223208.1 NZ_CP084209:c4035229-4034978 [Escherichia coli]
MRITIKRWGNSAGMVIPNIVMKELNLQPGQSVEAQVSNNQLILTPISRRYSLDELLAQCDMNAAELSEQDVWGKSTPAGD
EIW

Download         Length: 252 bp

>AT218296 NZ_CP115784:c181376-181131 [Paracoccus aerodenitrificans]
ATGGCAAAGAATACCTCAATGTCCCTTGGCGACCATTTCGCGGGGTTTATCGAATCGCAGGTCAGCAACGGTCGTTACGG
GTCTGCAAGCGAAGTCGTGCGCGCCGGGTTGCGGCTCCTCGAAGAGCAGGAGGCCAAGGTGCAGGCCTTGAAAGACGCCC
TGATTGCTGGAGAAAATTCCGGCGTTCCGCGCCCCCTTGATCGGGATGCCTTTCAGGCCCGGATGCGTCAAAAGCACCAA
TCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB U9XNP6

Antitoxin

Source ID Structure
AlphaFold DB A0A7U9LQ26

References