Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /Xre(antitoxin) |
| Location | 1519895..1521051 | Replicon | chromosome |
| Accession | NC_008740 | ||
| Organism | Marinobacter aquaeolei VT8 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | A1U0B1 |
| Locus tag | MAQU_RS06885 | Protein ID | WP_011784834.1 |
| Coordinates | 1519895..1520689 (-) | Length | 265 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | A0A833JS05 |
| Locus tag | MAQU_RS06890 | Protein ID | WP_011784835.1 |
| Coordinates | 1520686..1521051 (-) | Length | 122 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MAQU_RS06870 | 1515424..1516578 | + | 1155 | WP_011784831.1 | efflux RND transporter periplasmic adaptor subunit | - |
| MAQU_RS06875 | 1516575..1518509 | + | 1935 | WP_011784832.1 | MacB family efflux pump subunit | - |
| MAQU_RS06880 | 1518514..1519947 | + | 1434 | WP_011784833.1 | efflux transporter outer membrane subunit | - |
| MAQU_RS06885 | 1519895..1520689 | - | 795 | WP_011784834.1 | RES family NAD+ phosphorylase | Toxin |
| MAQU_RS06890 | 1520686..1521051 | - | 366 | WP_011784835.1 | MbcA/ParS/Xre antitoxin family protein | Antitoxin |
| MAQU_RS06895 | 1521118..1522677 | - | 1560 | WP_011784836.1 | FGGY-family carbohydrate kinase | - |
| MAQU_RS06900 | 1522670..1524268 | - | 1599 | WP_011784837.1 | glycerol-3-phosphate dehydrogenase/oxidase | - |
| MAQU_RS06905 | 1524276..1525880 | - | 1605 | WP_011784838.1 | FAD-binding oxidoreductase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 265 a.a. Molecular weight: 29875.96 Da Isoelectric Point: 9.3685
>T21825 WP_011784834.1 NC_008740:c1520689-1519895 [Marinobacter hydrocarbonoclasticus VT8]
MNYRERIAQSITPLQGNLFRVVESQEDIATARIVDSMQEQNRLEELLESNKPPVPGTARKRHYLLTTPFRYPPLKYGSRF
GRSFEPSLFYGAMSIPTALAETAFYRFVFMSHLKVPFKRPLTTLHTVFSARFRTERGVRLQSEHWQDLHHTLADPVSYRE
SQAVGTDMRSLQVGAFQFLSARALQAGLYALPYHPDNGVEGVNVALFNASVFRDAAPRSYQKLIAVTSPSQVSMSLSEPD
GSKKVYEFSLDQFLVEGELPQPAP
MNYRERIAQSITPLQGNLFRVVESQEDIATARIVDSMQEQNRLEELLESNKPPVPGTARKRHYLLTTPFRYPPLKYGSRF
GRSFEPSLFYGAMSIPTALAETAFYRFVFMSHLKVPFKRPLTTLHTVFSARFRTERGVRLQSEHWQDLHHTLADPVSYRE
SQAVGTDMRSLQVGAFQFLSARALQAGLYALPYHPDNGVEGVNVALFNASVFRDAAPRSYQKLIAVTSPSQVSMSLSEPD
GSKKVYEFSLDQFLVEGELPQPAP
Download Length: 795 bp
>T21825 NC_008740:c1520689-1519895 [Marinobacter hydrocarbonoclasticus VT8]
TTGAACTATCGGGAACGGATTGCCCAGTCCATCACACCGCTGCAAGGCAACCTGTTTCGGGTGGTGGAAAGTCAGGAAGA
CATCGCGACGGCACGCATCGTAGACAGTATGCAGGAACAGAATCGACTGGAGGAACTGCTGGAAAGCAACAAACCACCGG
TGCCCGGCACGGCCCGAAAACGCCATTACCTGCTGACCACCCCGTTCCGCTACCCGCCCCTGAAATACGGCTCACGTTTT
GGCCGCAGTTTCGAACCCAGTCTGTTTTACGGAGCCATGAGCATTCCCACGGCTCTGGCGGAAACCGCGTTTTATCGGTT
TGTATTCATGAGCCATCTGAAAGTCCCGTTCAAGCGCCCGTTAACCACCTTGCATACGGTGTTCAGCGCCCGATTCCGCA
CGGAACGAGGTGTTCGGCTGCAGTCTGAACACTGGCAGGATCTGCATCATACGCTGGCAGATCCAGTCAGCTACCGGGAA
AGCCAGGCTGTGGGTACCGACATGCGTAGCCTGCAAGTGGGCGCCTTCCAGTTTCTCTCAGCCCGCGCCCTGCAAGCCGG
CCTTTACGCTCTTCCGTACCATCCAGACAACGGCGTTGAGGGCGTCAATGTGGCCTTGTTTAACGCCAGCGTGTTCCGGG
ACGCCGCACCCAGAAGTTATCAAAAACTGATTGCCGTGACGTCGCCCAGCCAGGTGTCCATGAGCCTGTCGGAACCGGAT
GGCAGTAAAAAGGTTTACGAATTCAGCCTGGACCAGTTTCTGGTCGAAGGCGAACTACCTCAGCCGGCGCCGTAG
TTGAACTATCGGGAACGGATTGCCCAGTCCATCACACCGCTGCAAGGCAACCTGTTTCGGGTGGTGGAAAGTCAGGAAGA
CATCGCGACGGCACGCATCGTAGACAGTATGCAGGAACAGAATCGACTGGAGGAACTGCTGGAAAGCAACAAACCACCGG
TGCCCGGCACGGCCCGAAAACGCCATTACCTGCTGACCACCCCGTTCCGCTACCCGCCCCTGAAATACGGCTCACGTTTT
GGCCGCAGTTTCGAACCCAGTCTGTTTTACGGAGCCATGAGCATTCCCACGGCTCTGGCGGAAACCGCGTTTTATCGGTT
TGTATTCATGAGCCATCTGAAAGTCCCGTTCAAGCGCCCGTTAACCACCTTGCATACGGTGTTCAGCGCCCGATTCCGCA
CGGAACGAGGTGTTCGGCTGCAGTCTGAACACTGGCAGGATCTGCATCATACGCTGGCAGATCCAGTCAGCTACCGGGAA
AGCCAGGCTGTGGGTACCGACATGCGTAGCCTGCAAGTGGGCGCCTTCCAGTTTCTCTCAGCCCGCGCCCTGCAAGCCGG
CCTTTACGCTCTTCCGTACCATCCAGACAACGGCGTTGAGGGCGTCAATGTGGCCTTGTTTAACGCCAGCGTGTTCCGGG
ACGCCGCACCCAGAAGTTATCAAAAACTGATTGCCGTGACGTCGCCCAGCCAGGTGTCCATGAGCCTGTCGGAACCGGAT
GGCAGTAAAAAGGTTTACGAATTCAGCCTGGACCAGTTTCTGGTCGAAGGCGAACTACCTCAGCCGGCGCCGTAG
Antitoxin
Download Length: 122 a.a. Molecular weight: 13254.17 Da Isoelectric Point: 8.5039
>AT21825 WP_011784835.1 NC_008740:c1521051-1520686 [Marinobacter hydrocarbonoclasticus VT8]
MPEAVSAAPETSDKALLSKALLNAAKAFGLPQAEIAAVVGRNRTGLTRDGIDPASKSGELALLFIRLYRSVYALTGGERE
AMTHWLNTPNHYFEDTPRQMIQSTEGLVRVVHYLDAMRGRI
MPEAVSAAPETSDKALLSKALLNAAKAFGLPQAEIAAVVGRNRTGLTRDGIDPASKSGELALLFIRLYRSVYALTGGERE
AMTHWLNTPNHYFEDTPRQMIQSTEGLVRVVHYLDAMRGRI
Download Length: 366 bp
>AT21825 NC_008740:c1521051-1520686 [Marinobacter hydrocarbonoclasticus VT8]
ATGCCAGAAGCTGTTAGTGCAGCACCGGAAACCAGCGATAAAGCTCTGCTGTCCAAAGCCCTGCTGAACGCAGCCAAAGC
CTTTGGTTTGCCACAAGCGGAAATCGCGGCCGTGGTTGGCCGCAACCGCACAGGTTTGACCCGCGACGGCATTGATCCGG
CCAGTAAGTCGGGTGAACTGGCACTGTTGTTTATCCGGCTTTACCGCAGCGTCTATGCACTGACCGGCGGTGAACGGGAG
GCCATGACCCATTGGCTGAACACGCCCAACCACTATTTTGAGGATACACCCAGACAAATGATCCAGAGCACGGAAGGCCT
GGTTCGGGTGGTTCACTACCTGGACGCCATGCGGGGGCGGATTTGA
ATGCCAGAAGCTGTTAGTGCAGCACCGGAAACCAGCGATAAAGCTCTGCTGTCCAAAGCCCTGCTGAACGCAGCCAAAGC
CTTTGGTTTGCCACAAGCGGAAATCGCGGCCGTGGTTGGCCGCAACCGCACAGGTTTGACCCGCGACGGCATTGATCCGG
CCAGTAAGTCGGGTGAACTGGCACTGTTGTTTATCCGGCTTTACCGCAGCGTCTATGCACTGACCGGCGGTGAACGGGAG
GCCATGACCCATTGGCTGAACACGCCCAACCACTATTTTGAGGATACACCCAGACAAATGATCCAGAGCACGGAAGGCCT
GGTTCGGGTGGTTCACTACCTGGACGCCATGCGGGGGCGGATTTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A1U0B1 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A833JS05 |