Detailed information of TA system TA021824

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE-RelB
• Location: 712864..713437
• Replicon: chromosome
• Accession: NC_008740
• Organism: Marinobacter aquaeolei VT8

Toxin (Protein)

• Gene name: relE
• Uniprot ID: U7G998
• Locus tag: MAQU_RS03115
• Protein ID: WP_011784161.1
• Coordinates: 712864..713148 (-)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: MAQU_RS03120
• Protein ID: WP_031209720.1
• Coordinates: 713141..713437 (-)
• Length: 99 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MAQU_RS03090	708291..708686	-	396	WP_011784156.1	ectoine synthase	-
MAQU_RS03095	708906..710537	-	1632	WP_011784157.1	DHA2 family efflux MFS transporter permease subunit	-
MAQU_RS03100	710530..711720	-	1191	WP_198324799.1	HlyD family secretion protein	-
MAQU_RS03105	711734..712204	-	471	WP_011784159.1	transcriptional regulator SlyA	-
MAQU_RS03110	712352..712786	+	435	WP_011784160.1	universal stress protein	-
MAQU_RS03115	712864..713148	-	285	WP_011784161.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
MAQU_RS03120	713141..713437	-	297	WP_031209720.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
MAQU_RS03125	713514..713817	-	304	Protein_624	recombinase family protein	-
MAQU_RS03130	714017..714351	+	335	Protein_625	transposase	-
MAQU_RS03135	714582..715655	+	1074	WP_036149235.1	phospholipase A	-
MAQU_RS03140	715702..716823	-	1122	WP_011784164.1	ABC transporter permease	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-90)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (5-57)

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 10771.20 Da
• Isoelectric Point: 4.2183

>T21824 WP_011784161.1 NC_008740:c713148-712864 [Marinobacter hydrocarbonoclasticus VT8]
VPELEWLELARTDLLGIVDYISDDNPDAAQRVKDDIEMKAEKLPEFPTIGRPGRVEGTRELVAWSNYILVYQEDALTVRI
LRVLHAAQQWPPTD

Nucleotide

• Length: 285 bp

>T21824 NC_008740:c713148-712864 [Marinobacter hydrocarbonoclasticus VT8]
GTGCCTGAACTGGAATGGCTGGAACTGGCTCGTACCGATCTGCTAGGGATTGTCGATTACATCTCTGATGACAATCCCGA
TGCAGCACAGCGCGTAAAAGATGATATCGAGATGAAAGCTGAAAAGCTGCCGGAGTTCCCCACAATAGGCCGCCCTGGTC
GGGTTGAAGGGACCCGGGAACTCGTCGCCTGGTCGAACTATATCCTCGTGTACCAGGAGGATGCCTTGACGGTACGAATA
CTGCGCGTGTTACATGCTGCGCAGCAGTGGCCGCCAACCGATTAA

Antitoxin

Protein

• Length: 99 a.a.
• Molecular weight: 10839.41 Da
• Isoelectric Point: 6.8815

>AT21824 WP_031209720.1 NC_008740:c713437-713141 [Marinobacter hydrocarbonoclasticus VT8]
IMAHTSMLHVRVDDELKADAAEKLASFGLTVSDAVRILLTRVTKEGGLPVGLTADPEAHDAWFRDKVKEALADARPTVPH
QQVMDEAQALIDRKRRRA

Nucleotide

• Length: 297 bp

>AT21824 NC_008740:c713437-713141 [Marinobacter hydrocarbonoclasticus VT8]
ATCATGGCTCACACTTCAATGCTGCACGTTCGTGTGGACGACGAGCTGAAGGCTGATGCAGCGGAAAAGCTCGCCAGCTT
CGGCTTGACGGTATCAGATGCCGTCCGCATCCTTCTAACCCGCGTAACCAAAGAGGGCGGATTGCCCGTTGGGTTAACGG
CTGATCCGGAAGCCCATGACGCCTGGTTCCGCGATAAAGTGAAAGAGGCCCTGGCTGATGCCCGACCTACCGTTCCTCAT
CAACAGGTAATGGATGAGGCACAAGCGTTGATCGACAGAAAGCGTCGCCGTGCCTGA

Structures

Toxin

• AlphaFold DB: U7G998