Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | /RES-TIGR02293 |
Location | 550927..551837 | Replicon | plasmid pCB1A |
Accession | NZ_CP084198 | ||
Organism | Pantoea agglomerans strain CB1 |
Toxin (Protein)
Gene name | - | Uniprot ID | - |
Locus tag | LDO72_RS22015 | Protein ID | WP_069026891.1 |
Coordinates | 551367..551837 (+) | Length | 157 a.a. |
Antitoxin (Protein)
Gene name | - | Uniprot ID | - |
Locus tag | LDO72_RS22010 | Protein ID | WP_064703869.1 |
Coordinates | 550927..551370 (+) | Length | 148 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LDO72_RS21980 (LDO72_22000) | 545996..546844 | - | 849 | WP_022624593.1 | transporter substrate-binding domain-containing protein | - |
LDO72_RS21985 (LDO72_22005) | 546866..548053 | - | 1188 | WP_275103204.1 | M20 family metallopeptidase | - |
LDO72_RS21990 (LDO72_22010) | 548295..549194 | - | 900 | WP_163794437.1 | alpha/beta hydrolase | - |
LDO72_RS21995 (LDO72_22015) | 549245..549859 | - | 615 | WP_045139957.1 | TetR/AcrR family transcriptional regulator | - |
LDO72_RS22000 (LDO72_22020) | 550073..550490 | + | 418 | Protein_528 | LysR substrate-binding domain-containing protein | - |
LDO72_RS22005 (LDO72_22025) | 550525..550782 | - | 258 | Protein_529 | aldo/keto reductase | - |
LDO72_RS22010 (LDO72_22030) | 550927..551370 | + | 444 | WP_064703869.1 | DUF2384 domain-containing protein | Antitoxin |
LDO72_RS22015 (LDO72_22035) | 551367..551837 | + | 471 | WP_069026891.1 | RES family NAD+ phosphorylase | Toxin |
LDO72_RS22020 (LDO72_22040) | 552009..553040 | + | 1032 | WP_010670602.1 | AI-2E family transporter | - |
LDO72_RS22025 (LDO72_22045) | 553029..555758 | - | 2730 | WP_275103205.1 | cation-transporting P-type ATPase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | iroN | 1..569555 | 569555 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 157 a.a. Molecular weight: 17466.90 Da Isoelectric Point: 4.7699
>T218192 WP_069026891.1 NZ_CP084198:551367-551837 [Pantoea agglomerans]
MILYRLTKTKYLSTAWTGFGAKEAGGRWNSIGISMVYVSETASLTLLETLVHLHSAHILDAFTLLRIDVPDALIQTADIT
ELPANWADEDAPAELADYGDAWCSACDAVALRVPSALSPVEYNYLLNPEHPDFFRIVQQAEAIPFRFDRRLKPDRK
MILYRLTKTKYLSTAWTGFGAKEAGGRWNSIGISMVYVSETASLTLLETLVHLHSAHILDAFTLLRIDVPDALIQTADIT
ELPANWADEDAPAELADYGDAWCSACDAVALRVPSALSPVEYNYLLNPEHPDFFRIVQQAEAIPFRFDRRLKPDRK
Download Length: 471 bp
>T218192 NZ_CP115672:c3795425-3795015 [Enterobacter hormaechei]
GTGGTCCTGTGGCAATCTGATCTTCGCGTCTCCTGGCGCTCACAGTGGATGTCCTTACTGCTCCACGGTCTGGTGGCGGC
ACTGGTGTTATTGGTGCCGTGGCCGCTTAGCTATACCCCTCTGTGGTTGCTATTGCTGTCGTTTGTGGTGTTTGACAGCG
TGCGCAGCCAGCGTCGAATCAACGCCCGTCAGGGTGAAATTAAGCTGCTGATGGATTCTCGCCTGCGCTGGCAGGGAAAA
GAGTGGGAGATGATGGGCGCGCCGTGGATGCTTAACACCGGGATGATGCTACGGCTGCGTCGGGTCGAGGATAACCGTCG
CCAGCACCTGTGGCTGGCCGCAGACAGTATGGATCCCGCGGAGTGGCGAGATCTGCGCCGGTTGATCGTGCAACAGCCGA
CGCAGGAGTAA
GTGGTCCTGTGGCAATCTGATCTTCGCGTCTCCTGGCGCTCACAGTGGATGTCCTTACTGCTCCACGGTCTGGTGGCGGC
ACTGGTGTTATTGGTGCCGTGGCCGCTTAGCTATACCCCTCTGTGGTTGCTATTGCTGTCGTTTGTGGTGTTTGACAGCG
TGCGCAGCCAGCGTCGAATCAACGCCCGTCAGGGTGAAATTAAGCTGCTGATGGATTCTCGCCTGCGCTGGCAGGGAAAA
GAGTGGGAGATGATGGGCGCGCCGTGGATGCTTAACACCGGGATGATGCTACGGCTGCGTCGGGTCGAGGATAACCGTCG
CCAGCACCTGTGGCTGGCCGCAGACAGTATGGATCCCGCGGAGTGGCGAGATCTGCGCCGGTTGATCGTGCAACAGCCGA
CGCAGGAGTAA
Antitoxin
Download Length: 148 a.a. Molecular weight: 16463.84 Da Isoelectric Point: 9.9250
>AT218192 WP_064703869.1 NZ_CP084198:550927-551370 [Pantoea agglomerans]
MKTFSFSANKTRAPRLWQAAGLNNADGVALLGQINEGLDGNVAHLIVNWAKITQNDLRKMSGIPSTTFSRSVKAKFSAEQ
SERLVRIIRVIDRAVELFEGDKDEAQKWLNEPNRALSWKMPAELMASETGAYEVMKLITRLEHGVYS
MKTFSFSANKTRAPRLWQAAGLNNADGVALLGQINEGLDGNVAHLIVNWAKITQNDLRKMSGIPSTTFSRSVKAKFSAEQ
SERLVRIIRVIDRAVELFEGDKDEAQKWLNEPNRALSWKMPAELMASETGAYEVMKLITRLEHGVYS
Download Length: 444 bp
>AT218192 NZ_CP115672:c3795672-3795406 [Enterobacter hormaechei]
ATGGATATTAACAACAAGGCCCGTATTCACTGGGCGTGCCGTCGCGGCATGCGTGAACTTGATATCTCCATCATGCCTTT
CTTCGAGTATGAGTACGACAGCTTAAGCGATGACGATAAGCGCCTGTTTGTCCGTCTGCTTGAGTCTGACGATCCGGATT
TATTCAACTGGCTGATGAATCACGGCAAGCCCGCCGACACCGAGTTGCAACGGATGGTGCAATTAATTCAAACACGGAAT
CAGGAACGTGGTCCTGTGGCAATCTGA
ATGGATATTAACAACAAGGCCCGTATTCACTGGGCGTGCCGTCGCGGCATGCGTGAACTTGATATCTCCATCATGCCTTT
CTTCGAGTATGAGTACGACAGCTTAAGCGATGACGATAAGCGCCTGTTTGTCCGTCTGCTTGAGTCTGACGATCCGGATT
TATTCAACTGGCTGATGAATCACGGCAAGCCCGCCGACACCGAGTTGCAACGGATGGTGCAATTAATTCAAACACGGAAT
CAGGAACGTGGTCCTGTGGCAATCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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