Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 2663406..2664319 Replicon chromosome
Accession NZ_CP084115
Organism Cobetia amphilecti strain N-80

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag LCW13_RS11215 Protein ID WP_225346911.1
Coordinates 2663855..2664319 (+) Length 155 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag LCW13_RS11210 Protein ID WP_225346910.1
Coordinates 2663406..2663858 (+) Length 151 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LCW13_RS11180 (LCW13_11180) 2659116..2659997 + 882 WP_225346904.1 LysR family transcriptional regulator -
LCW13_RS11185 (LCW13_11185) 2660232..2660435 + 204 WP_225346905.1 hypothetical protein -
LCW13_RS11190 (LCW13_11190) 2660485..2660934 + 450 WP_225346906.1 GNAT family N-acetyltransferase -
LCW13_RS11195 (LCW13_11195) 2661672..2662136 + 465 WP_225346907.1 methylenetetrahydrofolate reductase C-terminal domain-containing protein -
LCW13_RS11200 (LCW13_11200) 2662133..2663104 + 972 WP_225346908.1 methylenetetrahydrofolate reductase -
LCW13_RS11205 (LCW13_11205) 2663191..2663373 + 183 WP_225346909.1 hypothetical protein -
LCW13_RS11210 (LCW13_11210) 2663406..2663858 + 453 WP_225346910.1 DUF2384 domain-containing protein Antitoxin
LCW13_RS11215 (LCW13_11215) 2663855..2664319 + 465 WP_225346911.1 RES family NAD+ phosphorylase Toxin
LCW13_RS11220 (LCW13_11220) 2665196..2666116 - 921 WP_225346912.1 SH3 domain-containing protein -
LCW13_RS11225 (LCW13_11225) 2666233..2666529 - 297 WP_225346913.1 DUF6447 family protein -
LCW13_RS11230 (LCW13_11230) 2666575..2667438 - 864 WP_225346914.1 OmpA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(7-149)

Antitoxin

Antitoxin Xre

(19-150)


Sequences

Toxin        


Download         Length: 155 a.a.        Molecular weight: 17371.81 Da        Isoelectric Point: 4.5160

>T218132 WP_225346911.1 NZ_CP084115:2663855-2664319 [Cobetia amphilecti]
MTVVRGYRLVKRKWLKTAFDGEGARLYGGRWNSKGKACVYLASTESLAMLEVMVHLEDNQLLKEYALLEVTFRQEVLMQL
PEDVLPADWRAEPAPPSTAEIGDDWLEGQSSLVLAVPSVVAPRETNYLVNPEHPDFLALAQNAEEVDFTPDRRL

Download         Length: 465 bp

>T218132 NZ_CP115628:2762-3049 [Acinetobacter baumannii]
ATGGAACAGTATTTTGAATGGGATGAGGCTAAGAATCGAAAGAATCAGAAAAAGCATGATATCTCTTTCGAAACTGCAAG
CCTTGTTTTTGAAGATCCATTACGGATCTCAATCCAAGACAGACATACCAATGGTGAAGAACGTTGGCAAACCATTGGAC
GAGTTAAAGGCGTACTAATGTTATTGGTGGCTCACACCATTTTTGATGAAGATGACTGTGAAATCATCCGAATCATTAGT
GCAAGGCAAGTCACTAAAGCGGAGCGAAACAAATATGAGCATGGTTAG

Antitoxin


Download         Length: 151 a.a.        Molecular weight: 16600.18 Da        Isoelectric Point: 10.1343

>AT218132 WP_225346910.1 NZ_CP084115:2663406-2663858 [Cobetia amphilecti]
MQAAIKEYRPKPTARKDDFWRALGLPSRGAKLHEALSAGISYKVYTKLTEASGLESKELARYVVIPPATLKRRADTGYFK
PAEGDRLYRFAEVYKSAMDLFEGDKAKAKEWLLSPVRGLGGRRPVEMVATTAGAEAVLDLIGRLEHGVFA

Download         Length: 453 bp

>AT218132 NZ_CP115628:3036-3350 [Acinetobacter baumannii]
ATGAGCATGGTTAGATACTCACACAAAGAGCTGAATGAGAAATTTGGTGAGAAGCAAGATGCTGAAATTCAACGCTTGCT
TGCTAAAGGCACGGTTCCTGATGATCAGCTAGATCTATCAGATATTCCTGAAATTACAGACTGGAGCAATGCTGTACGCC
AAAATCAATTTTACCGCCCAGTAAAGCAACAAACTTCAATTCGGTTAGATGCTGATGTACTTGCTTGGTTCAAAGCACAA
GGCAAAGGTTATCAAACACGTATGAATGAAATTTTACGAGATGCTATGCTAAAAGAATTAAAAAATCATCAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References