Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 188285..188800 Replicon chromosome
Accession NZ_CP084109
Organism Micrococcus luteus strain anQ-m1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LCP49_RS00835 Protein ID WP_134416751.1
Coordinates 188285..188539 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LCP49_RS00840 Protein ID WP_134416753.1
Coordinates 188540..188800 (-) Length 87 a.a.

Genomic Context

LCP49_RS00805LCP49_RS00810LCP49_RS00815LCP49_RS00820LCP49_RS00825LCP49_RS00845LCP49_RS00850LCP49_RS00855LCP49_RS00860LCP49_RS00865LCP49_RS00830LCP49_RS00835LCP49_RS00840
Location: 183791..185197 (1407 bp)
Type: Others
Protein ID: WP_163721243.1
Location: 185194..185583 (390 bp)
Type: Others
Protein ID: WP_163721241.1
Location: 185615..186352 (738 bp)
Type: Others
Protein ID: WP_205521335.1
Location: 186349..186891 (543 bp)
Type: Others
Protein ID: WP_134416745.1
Location: 186891..187673 (783 bp)
Type: Others
Protein ID: WP_134416747.1
Location: 188928..190271 (1344 bp)
Type: Others
Protein ID: WP_044658726.1
Location: 190446..190589 (144 bp)
Type: Others
Protein ID: WP_225348956.1
Location: 190586..191527 (942 bp)
Type: Others
Protein ID: WP_242821290.1
Location: 191557..192711 (1155 bp)
Type: Others
Protein ID: WP_225348580.1
Location: 192733..193122 (390 bp)
Type: Others
Protein ID: Protein_168
Location: 187717..188283 (567 bp)
Type: Others
Protein ID: WP_134416749.1
Location: 188285..188539 (255 bp)
Type: Toxin
Protein ID: WP_134416751.1
Location: 188540..188800 (261 bp)
Type: Antitoxin
Protein ID: WP_134416753.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
LCP49_RS00805183791..185197+1407WP_163721243.1Dyp-type peroxidase-
LCP49_RS00810185194..185583+390WP_163721241.1hypothetical protein-
LCP49_RS00815185615..186352+738WP_205521335.1histidine phosphatase family protein-
LCP49_RS00820186349..186891+543WP_134416745.1DUF3090 domain-containing protein-
LCP49_RS00825186891..187673+783WP_134416747.1SCO1664 family protein-
LCP49_RS00830187717..188283-567WP_134416749.1mismatch-specific DNA-glycosylase-
LCP49_RS00835188285..188539-255WP_134416751.1Txe/YoeB family addiction module toxinToxin
LCP49_RS00840188540..188800-261WP_134416753.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
LCP49_RS00845188928..190271+1344WP_044658726.1IS256-like element ISMlu11 family transposase-
LCP49_RS00850190446..190589+144WP_225348956.1hypothetical protein-
LCP49_RS00855190586..191527+942WP_242821290.1hypothetical protein-
LCP49_RS00860191557..192711+1155WP_225348580.1glycerate kinase-
LCP49_RS00865192733..193122+390Protein_168phosphatidylinositol kinase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-flankIS/Tn--188922..1902711349


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(3-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-70)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10024.39 Da        Isoelectric Point: 7.3149

>T218131 WP_134416751.1 NZ_CP084109:c188539-188285 [Micrococcus luteus]
VRLVWDRSAWEDYTHWQTTDRKVLKRINTLIDAALRDPFDGIGKPEQLKYGAPGAWSRRITEEHRLVYLVDGEDLIILQV
RYHY

Download         Length: 255 bp

>T218131 NZ_CP115627:c27427-27068 [Acinetobacter baumannii]
ATGGCTTGGGATGTAGAAACAACAGAACTTTTTGATTCTTGGTTGGCAGAACAAGATGAAAATGCTCAAGATAAAATCTT
AGCGTCTTTGCTTGTTTTGTCAGAACTGGGTCCAAATCTAGGCCGGCCTCATGTTGATACTATTAAAGAATCAAAATATC
CGAACATGAAAGAGATACGTGTGCAAGTTAAAGGTCATCCGATCCGTGGTTTCTTTGCATTTGATCCAGAACGTAAAGCC
ATTGTTTTGTGTGCTGGAGATAAGAAAGGGCTAAATGAAAAAGCCTTTTATAAAGAAATGATCAAGATTGCAGATGAACA
ATATGAGCAATATTTACGTGATAATTATGGAGATAAATAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9639.82 Da        Isoelectric Point: 4.8483

>AT218131 WP_134416753.1 NZ_CP084109:c188800-188540 [Micrococcus luteus]
MSISASEARKTLFPLIERVNADREVVEIVSRKGNAVLMPADEYAAWQETAYLFRSPANARRLLDAYERARAGSVEEHALD
RMDGDA

Download         Length: 261 bp

>AT218131 NZ_CP115627:c27068-26769 [Acinetobacter baumannii]
ATGGCTAAATTAAACGATATAATTTCAAAACGCTCACCTGAAAGCCAACAACGCATCAAGAAAATGGCAAATCAAATGCT
ATTGGATATTAACCTATCGAACCTACGGGAAGAGTTAAAAATATCTCAAGCTGAAATTGCAAAAAATCTAGGTGTAAGCC
AAGCTGCTATTTCAAAACGTGAAAAATTAGGTAAAGATCTTAAGATTTCATCATTAAAAGAATATGTTGAAGCTATGGGT
GGCAAAGTAAGGTTAGATGTTGAGTTACCTAACGGAAAGCATGTTGCTATATCTATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References