Detailed information of TA system TA218130

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): omega-epsilon-zeta/zeta-epsilon
• Location: 2228468..2229639
• Replicon: chromosome
• Accession: NZ_CP084108
• Organism: Lysinibacillus capsici strain anQ-h6

Toxin (Protein)

• Gene name: zeta
• Uniprot ID: -
• Locus tag: LCP48_RS10870
• Protein ID: WP_202341713.1
• Coordinates: 2228740..2229639 (+)
• Length: 300 a.a.

Antitoxin (Protein)

• Gene name: epsilon
• Uniprot ID: -
• Locus tag: LCP48_RS10865
• Protein ID: WP_004230939.1
• Coordinates: 2228468..2228743 (+)
• Length: 92 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LCP48_RS10845	2225237..2225944	+	708	WP_004230931.1	hypothetical protein	-
LCP48_RS10850	2225980..2226219	+	240	WP_004230933.1	PC4/YdbC family ssDNA-binding protein	-
LCP48_RS10855	2226223..2227359	+	1137	WP_225340957.1	ATPase, T2SS/T4P/T4SS family	-
LCP48_RS10860	2227356..2228096	+	741	WP_225340958.1	hypothetical protein	-
LCP48_RS10865	2228468..2228743	+	276	WP_004230939.1	hypothetical protein	Antitoxin
LCP48_RS10870	2228740..2229639	+	900	WP_202341713.1	zeta toxin family protein	Toxin
LCP48_RS10875	2229653..2229886	+	234	WP_225340959.1	hypothetical protein	-
LCP48_RS10880	2230084..2231202	+	1119	WP_225340960.1	S-layer homology domain-containing protein	-
LCP48_RS10885	2231277..2233328	+	2052	WP_225340961.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Zeta toxin domain (24-216)

Antitoxin

• Bacterial epsilon antitoxin (5-89)

Sequences

Toxin

Protein

• Length: 300 a.a.
• Molecular weight: 34477.26 Da
• Isoelectric Point: 6.9882

>T218130 WP_202341713.1 NZ_CP084108:2228740-2229639 [Lysinibacillus capsici]
MNKFDLAYFSEDEFQERLQFTIDRLSKKKKPFQKPVAYLLGGQAGAGKTTLHAIIKDKLNNDVITIDNDTFKQMHPNFDL
LVEKYGKDYVAHVTPFSNKMTEALIEHFSSQGFNLTIEGTLRTIETPMQTATSLKEKGYEVNLYAMAVSKDLSYLGTIER
YESMYLIDPQTARSTDKVIHDTIVSNLPDNLDMLFNSGYFAEISLFTREGTKVYSSVDTPSISPKQIIYEALNQEIPKDV
LINKIDHIIHLTKHNNHQVPDLLNWRKELIRQSISPFQDNEKKQDKVFNKVNKNKVFER

Nucleotide

• Length: 900 bp

>T218130 NZ_CP115626:448250-448639 [Acinetobacter baumannii]
TTGATCAACCATTTGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AGTTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAGCTTTATTTTCTTTT
TAAAGCGTCCGCAGCTTGCACAAATTGCTTATTTAGATAAAAAACTATGGTCGCTTGCTTATAAGTCACAGAACACCGTT
TCTCGCGTCAAAATTTTAAAAATAATTGATTGTCAGATTTTCATAGTGATCTATTTTGAAGGTCATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGCAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCTATTAA

Antitoxin

Protein

• Length: 92 a.a.
• Molecular weight: 10704.11 Da
• Isoelectric Point: 4.5702

>AT218130 WP_004230939.1 NZ_CP084108:2228468-2228743 [Lysinibacillus capsici]
MEKSLNYEQTFKIEVLNEFSNGVYARLLNFILKNGVDKNDSNNFYVSLLQQFSEMLNVDLFKMSNVELDNVKSYWENMND
YIKGITKEKSA

Nucleotide

• Length: 276 bp

>AT218130 NZ_CP115626:447986-448243 [Acinetobacter baumannii]
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTT
TGACCCTTATGTGAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCGTTGTTTGCTGAGTTGGTAGAACAGGAAG
ACCCTGATTTACTAGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAA
CACTATGTTCATGGTTAA