Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1856221..1856366 Replicon chromosome
Accession NZ_CP084103
Organism Klebsiella pneumoniae strain C11

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1856257..1856359 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1856221..1856366 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K8M04_RS08970 (K8M04_08960) 1851351..1853411 + 2061 WP_004151449.1 oligopeptidase B -
K8M04_RS08975 (K8M04_08965) 1853415..1854074 - 660 WP_002911407.1 exodeoxyribonuclease X -
K8M04_RS08980 (K8M04_08970) 1854153..1854383 - 231 WP_002911406.1 DNA polymerase III subunit theta -
K8M04_RS08985 (K8M04_08975) 1854496..1854870 + 375 WP_004151448.1 CopC domain-containing protein YobA -
K8M04_RS08990 (K8M04_08980) 1854874..1855743 + 870 WP_023282759.1 copper homeostasis membrane protein CopD -
K8M04_RS08995 (K8M04_08985) 1855760..1856098 + 339 WP_002911404.1 YebY family protein -
- 1856221..1856366 - 146 - - Antitoxin
- 1856257..1856359 + 103 - - Toxin
K8M04_RS09000 (K8M04_08990) 1856735..1856878 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
K8M04_RS09005 (K8M04_08995) 1856983..1857951 - 969 WP_014907334.1 VirK/YbjX family protein -
K8M04_RS09010 (K8M04_09000) 1858108..1858761 + 654 WP_016529030.1 protein-serine/threonine phosphatase -
K8M04_RS09015 (K8M04_09005) 1858758..1858949 - 192 WP_002911395.1 YebW family protein -
K8M04_RS09020 (K8M04_09010) 1859047..1859286 - 240 WP_040170325.1 YebV family protein -
K8M04_RS09025 (K8M04_09015) 1859402..1860835 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T218099 NZ_CP084103:1856257-1856359 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT218099 NZ_CP084103:c1856366-1856221 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References