Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VI Classification (family/domain) socAB/DUF4065(antitoxin)
Location 421270..422515 Replicon chromosome
Accession NC_008686
Organism Paracoccus denitrificans PD1222

Toxin (Protein)


Gene name socB Uniprot ID -
Locus tag PDEN_RS02240 Protein ID WP_128493026.1
Coordinates 421270..421971 (-) Length 234 a.a.

Antitoxin (Protein)


Gene name socA Uniprot ID -
Locus tag PDEN_RS02245 Protein ID WP_011746798.1
Coordinates 421964..422515 (-) Length 184 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PDEN_RS02230 419360..420268 + 909 WP_011746795.1 hypothetical protein -
PDEN_RS25930 420268..421179 + 912 WP_011746796.1 DNA polymerase III subunit epsilon -
PDEN_RS02240 421270..421971 - 702 WP_128493026.1 hypothetical protein Toxin
PDEN_RS02245 421964..422515 - 552 WP_011746798.1 SocA family protein Antitoxin
PDEN_RS02250 422858..423349 - 492 Protein_458 type I restriction endonuclease subunit R -
PDEN_RS02255 423504..423743 - 240 WP_074810467.1 hypothetical protein -
PDEN_RS02260 423758..424588 - 831 WP_011746800.1 hypothetical protein -
PDEN_RS02265 424675..424929 + 255 WP_011746801.1 helix-turn-helix domain-containing protein -
PDEN_RS25935 425120..425320 + 201 WP_074810464.1 hypothetical protein -
PDEN_RS02270 425511..425717 + 207 WP_198140517.1 helix-turn-helix domain-containing protein -
PDEN_RS25540 425929..426456 + 528 WP_011746803.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 412240..437371 25131


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin SocA-like, Panacea domain

(30-133)


Sequences

Toxin        


Download         Length: 234 a.a.        Molecular weight: 26805.37 Da        Isoelectric Point: 5.4840

>T21807 WP_128493026.1 NC_008686:c421971-421270 [Paracoccus denitrificans PD1222]
MPDIDLARIAPQRDDMKRKSLEQMKGGFSTFSYKPVRACFSDIFNIQPDLDLGSADPTPWTVIESELRKRSKSDEEFNYN
RRVALGLHDFATSGRVFGRRQEFFPLSMGMGQKVTFWLPMILAIDEQASALFIEPRRTRGLTAEGRRFALSMMHERIRAA
DEDFADVRLTIVQFSDPSDDRRAVRLHTDEGVELYSREDLEQMVASTYEMWRDVLEERENKARGKATGTGPLI

Download         Length: 702 bp

>T21807 NC_008686:c421971-421270 [Paracoccus denitrificans PD1222]
TTGCCTGACATTGACCTTGCGCGCATCGCGCCCCAACGCGATGACATGAAACGCAAGAGCTTGGAGCAGATGAAGGGCGG
TTTCTCGACCTTCTCCTACAAGCCGGTGCGCGCTTGCTTCTCTGACATCTTCAACATCCAGCCCGACTTGGACCTAGGGT
CAGCCGATCCGACGCCTTGGACTGTGATTGAGTCCGAGTTGCGGAAGCGCAGCAAGTCGGACGAGGAATTCAACTACAAC
CGGCGCGTTGCCCTTGGCCTGCACGACTTTGCGACTTCTGGTCGGGTCTTCGGGCGACGGCAGGAGTTCTTCCCGCTGTC
GATGGGCATGGGGCAGAAAGTCACATTCTGGCTGCCGATGATTCTCGCCATCGATGAGCAGGCAAGCGCCCTGTTTATCG
AACCGCGCCGCACCAGAGGCTTAACCGCCGAAGGCCGCAGGTTCGCGTTATCGATGATGCATGAGCGCATCCGGGCCGCT
GACGAGGACTTTGCCGACGTTCGATTGACCATCGTGCAGTTTAGCGACCCGTCTGATGATCGGCGCGCGGTCAGGCTCCA
CACGGACGAGGGCGTTGAACTCTACTCCCGCGAGGATTTGGAGCAGATGGTGGCTTCGACCTATGAGATGTGGCGCGATG
TGCTGGAAGAGCGCGAGAATAAGGCGCGGGGAAAGGCGACTGGTACTGGCCCGCTGATCTGA

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 20217.20 Da        Isoelectric Point: 9.9688

>AT21807 WP_011746798.1 NC_008686:c422515-421964 [Paracoccus denitrificans PD1222]
MSGPYDPRAIANLMLDEADRRGWKITNLALQKLLYFAHGIHLTKTKRPLVSGYFEAWQYGPVHPAVYRAFKPSGSAPIIN
RAAAKDPLTGKTRDLPKPTDLEVIDLVSDVMRSYGHLPPGRLVDLSHAKDSPWSVVVDKARTDVAFGMRIPDDVIIARFR
HHKVSVGTSPRAGEPPSDDAPFA

Download         Length: 552 bp

>AT21807 NC_008686:c422515-421964 [Paracoccus denitrificans PD1222]
ATGAGTGGGCCATACGATCCGAGGGCAATCGCGAACCTCATGCTGGACGAGGCGGATCGGCGCGGCTGGAAAATCACGAA
CCTTGCCCTCCAGAAGCTGCTCTACTTCGCTCACGGCATACACCTAACCAAGACGAAGCGCCCGCTCGTGTCGGGCTACT
TCGAGGCGTGGCAGTACGGCCCCGTGCATCCAGCCGTCTATCGGGCGTTCAAGCCGTCAGGCTCCGCACCCATCATCAAC
CGGGCGGCCGCGAAAGACCCGCTCACAGGCAAGACGCGTGATCTGCCAAAGCCGACGGACCTTGAAGTCATCGACCTCGT
GTCCGACGTGATGAGATCATACGGGCACCTCCCGCCTGGACGGCTGGTCGATCTGTCCCACGCGAAGGACTCGCCGTGGT
CGGTGGTCGTGGACAAAGCACGAACAGATGTTGCTTTTGGGATGCGGATACCGGATGATGTGATCATCGCCCGATTCCGC
CACCATAAGGTGTCGGTCGGCACAAGTCCTCGTGCAGGAGAACCGCCTAGTGACGACGCGCCTTTTGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References