Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | pasABC/RelE-HTH |
| Location | 1573727..1574219 | Replicon | chromosome |
| Accession | NC_008639 | ||
| Organism | Chlorobium phaeobacteroides DSM 266 | ||
Toxin (Protein)
| Gene name | pasB | Uniprot ID | A1BG78 |
| Locus tag | CPHA266_RS07090 | Protein ID | WP_011745223.1 |
| Coordinates | 1573727..1573987 (-) | Length | 87 a.a. |
Antitoxin (Protein)
| Gene name | pasA | Uniprot ID | - |
| Locus tag | CPHA266_RS07095 | Protein ID | WP_081428225.1 |
| Coordinates | 1573971..1574219 (-) | Length | 83 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CPHA266_RS07070 | 1569108..1570316 | - | 1209 | WP_011745220.1 | hypothetical protein | - |
| CPHA266_RS07075 | 1571301..1572392 | - | 1092 | WP_011745221.1 | hypothetical protein | - |
| CPHA266_RS14705 | 1572973..1573101 | + | 129 | Protein_1387 | type II toxin-antitoxin system MqsR family toxin | - |
| CPHA266_RS07085 | 1573139..1573549 | + | 411 | WP_011745222.1 | type II toxin-antitoxin system MqsA family antitoxin | - |
| CPHA266_RS07090 | 1573727..1573987 | - | 261 | WP_011745223.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| CPHA266_RS07095 | 1573971..1574219 | - | 249 | WP_081428225.1 | ribbon-helix-helix protein, CopG family | Antitoxin |
| CPHA266_RS07100 | 1574662..1574904 | + | 243 | WP_011745226.1 | ribbon-helix-helix domain-containing protein | - |
| CPHA266_RS07105 | 1574889..1575233 | + | 345 | WP_011745227.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| CPHA266_RS07110 | 1575249..1575449 | - | 201 | WP_150081078.1 | hypothetical protein | - |
| CPHA266_RS07115 | 1575439..1575690 | + | 252 | WP_011745228.1 | ribbon-helix-helix domain-containing protein | - |
| CPHA266_RS07120 | 1575727..1576095 | + | 369 | WP_081428226.1 | putative toxin-antitoxin system toxin component, PIN family | - |
| CPHA266_RS07125 | 1576336..1576866 | + | 531 | WP_011743929.1 | winged helix-turn-helix domain-containing protein | - |
| CPHA266_RS15195 | 1576884..1577159 | + | 276 | Protein_1397 | transposase | - |
| CPHA266_RS14710 | 1577699..1577860 | + | 162 | WP_011745230.1 | DUF4160 domain-containing protein | - |
| CPHA266_RS07135 | 1577925..1578137 | + | 213 | WP_150081201.1 | DUF4160 domain-containing protein | - |
| CPHA266_RS07140 | 1578141..1578383 | + | 243 | WP_011745232.1 | DUF2442 domain-containing protein | - |
| CPHA266_RS07145 | 1578501..1578770 | + | 270 | WP_041467251.1 | hypothetical protein | - |
| CPHA266_RS07150 | 1578767..1579066 | + | 300 | WP_011745234.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 87 a.a. Molecular weight: 10041.72 Da Isoelectric Point: 10.6169
>T21802 WP_011745223.1 NC_008639:c1573987-1573727 [Chlorobium phaeobacteroides DSM 266]
MVWKIEFASSAEKELARLDKSAARRIVKYLRERVAIDPRASGKSLRGDHAGLWRYRIGDYRVICEILDEKVSVLVVRVGH
RKEVYR
MVWKIEFASSAEKELARLDKSAARRIVKYLRERVAIDPRASGKSLRGDHAGLWRYRIGDYRVICEILDEKVSVLVVRVGH
RKEVYR
Download Length: 261 bp
>T21802 NC_008639:c1573987-1573727 [Chlorobium phaeobacteroides DSM 266]
TTGGTCTGGAAGATTGAGTTTGCCTCATCGGCTGAAAAAGAGCTGGCCAGGCTGGATAAGTCCGCTGCCAGACGGATTGT
CAAATACCTCCGTGAACGGGTTGCGATAGACCCGCGGGCTTCCGGCAAATCATTACGAGGCGATCATGCCGGGTTGTGGC
GATACCGTATCGGAGATTATCGGGTGATTTGCGAAATCCTCGATGAAAAAGTTTCAGTTCTTGTTGTCCGGGTCGGGCAT
CGGAAAGAGGTTTACCGGTAA
TTGGTCTGGAAGATTGAGTTTGCCTCATCGGCTGAAAAAGAGCTGGCCAGGCTGGATAAGTCCGCTGCCAGACGGATTGT
CAAATACCTCCGTGAACGGGTTGCGATAGACCCGCGGGCTTCCGGCAAATCATTACGAGGCGATCATGCCGGGTTGTGGC
GATACCGTATCGGAGATTATCGGGTGATTTGCGAAATCCTCGATGAAAAAGTTTCAGTTCTTGTTGTCCGGGTCGGGCAT
CGGAAAGAGGTTTACCGGTAA
Antitoxin
Download Length: 83 a.a. Molecular weight: 9680.01 Da Isoelectric Point: 4.7971
>AT21802 WP_081428225.1 NC_008639:c1574219-1573971 [Chlorobium phaeobacteroides DSM 266]
MEKEKADRMIGIRIPKSVGERLDNLAKRTGRTRTWYIREAIMEHLDDLEDIYLAEQVLERVRRGEEPVTGIDEVERRLGL
ED
MEKEKADRMIGIRIPKSVGERLDNLAKRTGRTRTWYIREAIMEHLDDLEDIYLAEQVLERVRRGEEPVTGIDEVERRLGL
ED
Download Length: 249 bp
>AT21802 NC_008639:c1574219-1573971 [Chlorobium phaeobacteroides DSM 266]
ATGGAAAAAGAGAAAGCGGATCGGATGATCGGCATCCGCATTCCGAAAAGTGTTGGCGAGCGGCTTGATAATCTTGCCAA
AAGAACCGGTCGTACCAGGACCTGGTACATCCGCGAGGCCATTATGGAGCATCTCGACGATCTTGAAGATATCTATCTGG
CCGAACAGGTTCTGGAGCGGGTGAGACGTGGTGAAGAGCCGGTGACCGGCATAGATGAAGTGGAGCGTCGTCTTGGTCTG
GAAGATTGA
ATGGAAAAAGAGAAAGCGGATCGGATGATCGGCATCCGCATTCCGAAAAGTGTTGGCGAGCGGCTTGATAATCTTGCCAA
AAGAACCGGTCGTACCAGGACCTGGTACATCCGCGAGGCCATTATGGAGCATCTCGACGATCTTGAAGATATCTATCTGG
CCGAACAGGTTCTGGAGCGGGTGAGACGTGGTGAAGAGCCGGTGACCGGCATAGATGAAGTGGAGCGTCGTCTTGGTCTG
GAAGATTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|