Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 1573727..1574219 Replicon chromosome
Accession NC_008639
Organism Chlorobium phaeobacteroides DSM 266

Toxin (Protein)


Gene name pasB Uniprot ID A1BG78
Locus tag CPHA266_RS07090 Protein ID WP_011745223.1
Coordinates 1573727..1573987 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag CPHA266_RS07095 Protein ID WP_081428225.1
Coordinates 1573971..1574219 (-) Length 83 a.a.

Genomic Context

CPHA266_RS14705CPHA266_RS07085CPHA266_RS07100CPHA266_RS07105CPHA266_RS07115CPHA266_RS07120CPHA266_RS07125CPHA266_RS15195CPHA266_RS14710CPHA266_RS07135CPHA266_RS07140CPHA266_RS07145CPHA266_RS07150CPHA266_RS07070CPHA266_RS07075CPHA266_RS07090CPHA266_RS07095CPHA266_RS07110
Location: 1572973..1573101 (129 bp)
Type: Others
Protein ID: Protein_1387
Location: 1573139..1573549 (411 bp)
Type: Others
Protein ID: WP_011745222.1
Location: 1574662..1574904 (243 bp)
Type: Others
Protein ID: WP_011745226.1
Location: 1574889..1575233 (345 bp)
Type: Others
Protein ID: WP_011745227.1
Location: 1575439..1575690 (252 bp)
Type: Others
Protein ID: WP_011745228.1
Location: 1575727..1576095 (369 bp)
Type: Others
Protein ID: WP_081428226.1
Location: 1576336..1576866 (531 bp)
Type: Others
Protein ID: WP_011743929.1
Location: 1576884..1577159 (276 bp)
Type: Others
Protein ID: Protein_1397
Location: 1577699..1577860 (162 bp)
Type: Others
Protein ID: WP_011745230.1
Location: 1577925..1578137 (213 bp)
Type: Others
Protein ID: WP_150081201.1
Location: 1578141..1578383 (243 bp)
Type: Others
Protein ID: WP_011745232.1
Location: 1578501..1578770 (270 bp)
Type: Others
Protein ID: WP_041467251.1
Location: 1578767..1579066 (300 bp)
Type: Others
Protein ID: WP_011745234.1
Location: 1569108..1570316 (1209 bp)
Type: Others
Protein ID: WP_011745220.1
Location: 1571301..1572392 (1092 bp)
Type: Others
Protein ID: WP_011745221.1
Location: 1573727..1573987 (261 bp)
Type: Toxin
Protein ID: WP_011745223.1
Location: 1573971..1574219 (249 bp)
Type: Antitoxin
Protein ID: WP_081428225.1
Location: 1575249..1575449 (201 bp)
Type: Others
Protein ID: WP_150081078.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
CPHA266_RS070701569108..1570316-1209WP_011745220.1hypothetical protein-
CPHA266_RS070751571301..1572392-1092WP_011745221.1hypothetical protein-
CPHA266_RS147051572973..1573101+129Protein_1387type II toxin-antitoxin system MqsR family toxin-
CPHA266_RS070851573139..1573549+411WP_011745222.1type II toxin-antitoxin system MqsA family antitoxin-
CPHA266_RS070901573727..1573987-261WP_011745223.1type II toxin-antitoxin system RelE/ParE family toxinToxin
CPHA266_RS070951573971..1574219-249WP_081428225.1ribbon-helix-helix protein, CopG familyAntitoxin
CPHA266_RS071001574662..1574904+243WP_011745226.1ribbon-helix-helix domain-containing protein-
CPHA266_RS071051574889..1575233+345WP_011745227.1type II toxin-antitoxin system PemK/MazF family toxin-
CPHA266_RS071101575249..1575449-201WP_150081078.1hypothetical protein-
CPHA266_RS071151575439..1575690+252WP_011745228.1ribbon-helix-helix domain-containing protein-
CPHA266_RS071201575727..1576095+369WP_081428226.1putative toxin-antitoxin system toxin component, PIN family-
CPHA266_RS071251576336..1576866+531WP_011743929.1winged helix-turn-helix domain-containing protein-
CPHA266_RS151951576884..1577159+276Protein_1397transposase-
CPHA266_RS147101577699..1577860+162WP_011745230.1DUF4160 domain-containing protein-
CPHA266_RS071351577925..1578137+213WP_150081201.1DUF4160 domain-containing protein-
CPHA266_RS071401578141..1578383+243WP_011745232.1DUF2442 domain-containing protein-
CPHA266_RS071451578501..1578770+270WP_041467251.1hypothetical protein-
CPHA266_RS071501578767..1579066+300WP_011745234.1type II toxin-antitoxin system RelE/ParE family toxin-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-85)

Antitoxin

Ribbon-helix-helix protein, CopG

(10-46)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10041.72 Da        Isoelectric Point: 10.6169

>T21802 WP_011745223.1 NC_008639:c1573987-1573727 [Chlorobium phaeobacteroides DSM 266]
MVWKIEFASSAEKELARLDKSAARRIVKYLRERVAIDPRASGKSLRGDHAGLWRYRIGDYRVICEILDEKVSVLVVRVGH
RKEVYR

Download         Length: 261 bp

>T21802 NC_008639:c1573987-1573727 [Chlorobium phaeobacteroides DSM 266]
TTGGTCTGGAAGATTGAGTTTGCCTCATCGGCTGAAAAAGAGCTGGCCAGGCTGGATAAGTCCGCTGCCAGACGGATTGT
CAAATACCTCCGTGAACGGGTTGCGATAGACCCGCGGGCTTCCGGCAAATCATTACGAGGCGATCATGCCGGGTTGTGGC
GATACCGTATCGGAGATTATCGGGTGATTTGCGAAATCCTCGATGAAAAAGTTTCAGTTCTTGTTGTCCGGGTCGGGCAT
CGGAAAGAGGTTTACCGGTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9680.01 Da        Isoelectric Point: 4.7971

>AT21802 WP_081428225.1 NC_008639:c1574219-1573971 [Chlorobium phaeobacteroides DSM 266]
MEKEKADRMIGIRIPKSVGERLDNLAKRTGRTRTWYIREAIMEHLDDLEDIYLAEQVLERVRRGEEPVTGIDEVERRLGL
ED

Download         Length: 249 bp

>AT21802 NC_008639:c1574219-1573971 [Chlorobium phaeobacteroides DSM 266]
ATGGAAAAAGAGAAAGCGGATCGGATGATCGGCATCCGCATTCCGAAAAGTGTTGGCGAGCGGCTTGATAATCTTGCCAA
AAGAACCGGTCGTACCAGGACCTGGTACATCCGCGAGGCCATTATGGAGCATCTCGACGATCTTGAAGATATCTATCTGG
CCGAACAGGTTCTGGAGCGGGTGAGACGTGGTGAAGAGCCGGTGACCGGCATAGATGAAGTGGAGCGTCGTCTTGGTCTG
GAAGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA1BG78

Antitoxin

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Source
ID
Structure
No matching records found

References