Detailed information of TA system TA218005

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 4767211..4767746
• Replicon: chromosome
• Accession: NZ_CP084032
• Organism: Pectobacterium colocasium strain LJ1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: LCF41_RS21550
• Protein ID: WP_225086276.1
• Coordinates: 4767459..4767746 (+)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: Q6DB37
• Locus tag: LCF41_RS21545
• Protein ID: WP_010281712.1
• Coordinates: 4767211..4767462 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LCF41_RS21520	4763471..4763797	+	327	WP_225086271.1	helix-turn-helix domain-containing protein	-
LCF41_RS21525	4763782..4764096	+	315	WP_225086272.1	HipA N-terminal domain-containing protein	-
LCF41_RS21530	4764093..4765133	+	1041	WP_225086273.1	HipA domain-containing protein	-
LCF41_RS21535	4765243..4765998	+	756	WP_225086274.1	thiol:disulfide interchange protein DsbG	-
LCF41_RS21540	4766033..4766938	-	906	WP_225086275.1	siderophore-interacting protein	-
LCF41_RS21545	4767211..4767462	+	252	WP_010281712.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
LCF41_RS21550	4767459..4767746	+	288	WP_225086276.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
LCF41_RS21555	4767848..4769200	-	1353	WP_225086277.1	glutathione-disulfide reductase	-
LCF41_RS21560	4769329..4770171	-	843	WP_225086278.1	23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ	-
LCF41_RS21565	4770414..4771118	+	705	WP_225086279.1	DUF1266 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-84)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 10983.06 Da
• Isoelectric Point: 10.3544

>T218005 WP_225086276.1 NZ_CP084032:4767459-4767746 [Pectobacterium colocasium]
MSYSVKFREDALKEWCKLGKTIQQQFAKKLKKCCENPHIPSAKLRGMKDCYKIKLRASGFRLVYEVIDDILVIAVVAVGK
RERSGVYNLASERMR

Nucleotide

• Length: 288 bp

>T218005 NZ_CP115175:44614-44862 [Homoserinibacter sp. YIM 151385]
ATGGCCATCACCGCGAGCGAGGCCCGAGCCGATCTCTTCGGCCTCATCGAGCGCGTCAACCTCGACCACATCGAGGTCGA
GATCACGTCGAAGCGCGGTGCCGCGGTCATCATGTCGAAGGACGAGTACGACGCGCTCATCGAGACCGCTCATCTGCTCC
GATCGCCCGCCAACGCACGTCGACTGCTGCGCGCGCTCGACAGCGCACGGGCCGGCGCGGGCACCGAGCGCGAGCCGATC
GAGGGATGA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9117.47 Da
• Isoelectric Point: 4.0637

>AT218005 WP_010281712.1 NZ_CP084032:4767211-4767462 [Pectobacterium colocasium]
MPNIILSDTSASVSELKKNPMATVNAGDGLPVAILNRNQPAFYCIPADLYEKMLDALDDQELVKLIGERKNQPLVDVDLD
SFL

Nucleotide

• Length: 252 bp

>AT218005 NZ_CP115175:44859-45122 [Homoserinibacter sp. YIM 151385]
ATGACGCGCCGACTCGTCTGGGTCGACGAGGCCTGGGAGGACTACCTCCACTGGCAGGGGCAGGATCGGAAGACCCTCAA
GCGGATCAACCTGCTCATCGCGGATGTCCGCCGCGGCGATCCCTTCGAGGGGATCGGCAAGCCGGAGCCGCTCAAGCACG
CGCTCGCGGGAGCGTGGTCGCGGCGGATCGACGACGTCAACCGGCTCGTCTACATCGCGGATGCGGAGTCGGTCACGATC
CTCCAGGCGCGATACCACTACTGA

Structures

Antitoxin

• AlphaFold DB: A0A0M2EZP0