Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vagCD/VapC-VagC
Location 3943249..3943889 Replicon chromosome
Accession NZ_CP084032
Organism Pectobacterium colocasium strain LJ1

Toxin (Protein)


Gene name vagD Uniprot ID -
Locus tag LCF41_RS17880 Protein ID WP_225085720.1
Coordinates 3943249..3943665 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag LCF41_RS17885 Protein ID WP_225085721.1
Coordinates 3943662..3943889 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LCF41_RS17850 3938324..3938938 + 615 WP_225085717.1 YitT family protein -
LCF41_RS17855 3939003..3940196 + 1194 WP_225085718.1 amino acid aminotransferase -
LCF41_RS17860 3940280..3940777 + 498 WP_225085719.1 M48 family metallopeptidase -
LCF41_RS17865 3941232..3941456 + 225 Protein_3487 type VI secretion system tube protein TssD -
LCF41_RS17870 3941521..3941927 - 407 Protein_3488 DUF1240 domain-containing protein -
LCF41_RS17875 3941920..3942776 - 857 Protein_3489 hypothetical protein -
LCF41_RS17880 3943249..3943665 - 417 WP_225085720.1 type II toxin-antitoxin system VapC family toxin Toxin
LCF41_RS17885 3943662..3943889 - 228 WP_225085721.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
LCF41_RS17890 3944152..3944571 - 420 WP_225085722.1 secondary thiamine-phosphate synthase enzyme YjbQ -
LCF41_RS17895 3944588..3947422 - 2835 WP_225085723.1 excinuclease ABC subunit UvrA -
LCF41_RS17900 3947667..3948206 + 540 WP_225085724.1 single-stranded DNA-binding protein SSB1 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(6-129)

Antitoxin

SpoVT-AbrB domain

(7-55)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15120.69 Da        Isoelectric Point: 8.5225

>T218002 WP_225085720.1 NZ_CP084032:c3943665-3943249 [Pectobacterium colocasium]
VSCLFMLDTNICSFIMREHPAAVIDKLQQCTLRRDRIVVSAITYAEMRFGAVGKKASPRHMQLVDAFCRRLDAVLPWDSA
AVDATTKIKIALAAVGTPIGPNDAAIAGHAISAKAILVTNNLREFERVQGLTLEDWVK

Download         Length: 417 bp

>T218002 NZ_CP115174:c3926459-3926214 [Sphingomonas sp. PAMB00755]
GTGATCATCGTCTGGGATGAACCGAAACGCGAAGCGAACCTTGCCAAGCATGGCATCGATTTCGCTGACATCGGCGAAAG
CTTCTTCGCCTCTGCCATCGTCCGTCCTTCGCGCGCAGGCCGCTTCGCAGCCTTCGGGGAACTGAACGGCAAGATTGCGG
TGATCTTTCTCGCACTGGGAACCGAGGGTATCTCGATCATCTCGGCCCGGCCCGCCAGCCGGAAGGAAAGGAGGCTGATG
CCATGA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8907.13 Da        Isoelectric Point: 4.8483

>AT218002 WP_225085721.1 NZ_CP084032:c3943889-3943662 [Pectobacterium colocasium]
MRIVSVFKNGNNRAIRLPRDMDFEGVNELEIVREGDTIMLRPVKPNWHSFLQEERADADFMTERQDVIEEGRFKL

Download         Length: 228 bp

>AT218002 NZ_CP115174:c3926217-3925951 [Sphingomonas sp. PAMB00755]
ATGACCGAACCGAAATACACACAGGCCGATCTCGATGCCGTGTCAGACAATCCCGAATGGACGGCGGCAGATTTCGCCGA
GGCGAAGCCCTTCGCCGAAGCGTTCCCCGAACTGGCACAATCGAAGCGGGGGCCGCAGCGGAAGCCGACGAAAGTCAGCA
CAACAATCCGCCTCTCGCCGGACGTGCTTGACCGCTTCAAGGCAGGCGGACCCGGCTGGCAAAGTCGGATCGATGATGCG
CTTCGCAAGGCTGTAGGCTTGGGCTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References