Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 1985847..1986417 Replicon chromosome
Accession NZ_CP084032
Organism Pectobacterium colocasium strain LJ1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LCF41_RS09020 Protein ID WP_225087761.1
Coordinates 1986133..1986417 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LCF41_RS09015 Protein ID WP_225088127.1
Coordinates 1985847..1986086 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LCF41_RS08985 1981536..1982072 + 537 WP_225087756.1 rhodanese family protein -
LCF41_RS08990 1982137..1982466 + 330 WP_225087757.1 DHCW motif cupin fold protein -
LCF41_RS22250 1982710..1982997 + 288 WP_284144952.1 GyrI-like domain-containing protein -
LCF41_RS22255 1983009..1983173 + 165 WP_284144953.1 hypothetical protein -
LCF41_RS09000 1983337..1984215 - 879 WP_225087759.1 cell envelope biogenesis protein OmpA -
LCF41_RS09005 1984865..1985095 - 231 Protein_1757 integrase arm-type DNA-binding domain-containing protein -
LCF41_RS09010 1985430..1985789 - 360 WP_225087760.1 hypothetical protein -
LCF41_RS09015 1985847..1986086 - 240 WP_225088127.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LCF41_RS09020 1986133..1986417 - 285 WP_225087761.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LCF41_RS09025 1986407..1986652 - 246 WP_225087762.1 CopG family ribbon-helix-helix protein -
LCF41_RS09030 1987387..1988709 + 1323 WP_225087763.1 DUF4062 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1947009..2008913 61904


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(2-77)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11157.97 Da        Isoelectric Point: 10.0520

>T218001 WP_225087761.1 NZ_CP084032:c1986417-1986133 [Pectobacterium colocasium]
MEIKWLRKSAANLEAEYRYIAQDDPQAASQFIDEVQRLTELLPQQPAMGRPGRVLGTRELVLTHYPYIIPYRVKDNMIQI
LRVFHTHRRLPAKW

Download         Length: 285 bp

>T218001 NZ_CP115174:721651-722181 [Sphingomonas sp. PAMB00755]
ATGAGCCGGCCGCCGAAGAACATGGCGATGTCGGTGCGCGACCGGCTGACGGCGCGGGCGCGCGAACGTCGGGAAAACGC
ACAGCTGCTCATGACCCGATACGTCATCGAACGTCTGCTCTTTCGCCTGAGCCTGTCGCCGCACCGCGAGCGGTTCGTCC
TCAAGGGCGCGATGCTGTTCAGCCTGTGGACGGCAGCCCCCTATCGCGCCACCGGCGACCTCGATCTGCTCGGCATGGGC
GAGAACGCACCCGAGCAGCTCGCGGCGATCTTTCAGGAAATCCTCGCGGTGACGGTCGATGACGACGGAATCGTGTTCCG
GCCCGAAACCCTCCGCGCAGCCGCAGCCCGCGCCGAGGATGAATATTCCGGCGTACGTATCGACTTCGTCGCCGAACTCG
CAGGCGCGCGCCTGCCGATGCACGTCGATATCGGCTTTGGCGACGCGATCACTCCGGGCGCGATGGCGCTCGGCCAAGGC
GGAAGCTTCGACGGCGAGTGGCCCAGCGGAGGTCCGTGGAAGGCAAAGTGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9217.62 Da        Isoelectric Point: 5.7185

>AT218001 WP_225088127.1 NZ_CP084032:c1986086-1985847 [Pectobacterium colocasium]
MGNVTFRIDDDLKRRSYAALKKLGITPSEALRLTLEYVAENERLPFKQKLLNDEDVELVEVVREHLHNPKPVRMTLDDL

Download         Length: 240 bp

>AT218001 NZ_CP115174:721046-721654 [Sphingomonas sp. PAMB00755]
GTGGAAACGACGACTCATCGAGAACGGGCCCTGGCAGTCGTCCGGCACTGCGGCATCGCGCGCGGCCGCGATTTCGACGC
GGCCGGGGTCACGCGCGCCACCCTACAGCGGCTGCGCGACGAAGGCGTCCTCCAGCAGGTCGGCCGCGGACTCTACAAGC
TGGCCGATGCTGACGTCGACAGTGCGACGAGCCTAGCCGAGGCCGTGCGCATCCAGCCGCGCGGAATCATCTGCCTGCTC
TCGGCGCTGCAGTTCCACGAGCTGACCACCCAGACCCCCCATGCGGTATGGATGATGCTCGGCCAAAAGGACTGGGCACC
GGTCAATCCATCCGTGGCGCTGAAGATCGTTCGCGCGAGCGGCGAAGCGCTGACAGCGGGCGTGGAGACACAGGTCATCG
ACGGCGTTCCCGTGCCCATCACCGTACCGGCCAAGACCGTCGCCGATTGCTTCAAGCACCGCAACAAGATCGGTATCGAC
GTGGCGGTCGAGGCCCTGCGCGATTTCATGAAGTCCCGGCCCCGGCCGGACCTCAATGCGATCTACCGTTATGCGCAGCT
CGATCGGGTCCAATCGGTGATCCGGCCCTATCTCGAAGCGATGACATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References