217999

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 1268939..1269564 Replicon chromosome
Accession NZ_CP084032
Organism Pectobacterium colocasium strain LJ1

Toxin (Protein)


Gene name Hha Uniprot ID C6DB72
Locus tag LCF41_RS05595 Protein ID WP_005976087.1
Coordinates 1268939..1269142 (-) Length 68 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID C6DB73
Locus tag LCF41_RS05600 Protein ID WP_005976089.1
Coordinates 1269196..1269564 (-) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LCF41_RS05565 1264454..1264792 + 339 WP_002208627.1 P-II family nitrogen regulator -
LCF41_RS05570 1264832..1266118 + 1287 WP_225087233.1 ammonium transporter AmtB -
LCF41_RS05575 1266196..1267059 - 864 WP_225087234.1 acyl-CoA thioesterase II -
LCF41_RS05580 1267272..1267853 + 582 WP_225087235.1 YbaY family lipoprotein -
LCF41_RS05585 1267874..1268194 - 321 WP_015839360.1 MGMT family protein -
LCF41_RS05595 1268939..1269142 - 204 WP_005976087.1 HHA domain-containing protein Toxin
LCF41_RS05600 1269196..1269564 - 369 WP_005976089.1 Hha toxicity modulator TomB Antitoxin
LCF41_RS05605 1270161..1270304 - 144 WP_005976091.1 type B 50S ribosomal protein L36 -
LCF41_RS05610 1270322..1270570 - 249 WP_225087236.1 type B 50S ribosomal protein L31 -
LCF41_RS05615 1270801..1273929 - 3129 WP_225087237.1 efflux RND transporter permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(8-64)

Antitoxin

Biofilm formation regulator YbaJ

(1-118)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 8145.52 Da        Isoelectric Point: 8.9008

>T217999 WP_005976087.1 NZ_CP084032:c1269142-1268939 [Pectobacterium colocasium]
MKKIDYLMRLRKCTTIDTLERVIEKNKYELSNDELEMFFSAADHRLAELTMNKLYDKVPTAVWRYVR

Download         Length: 204 bp

>T217999 NZ_CP115172:c3220258-3219908 [Bacillus safensis]
TTGATTGTTAAACGCGGTGATGTTTACTTTGCTGATTTATCTCCTGTTGTTGGCTCCGAGCAGGGCGGGGTTCGCCCAGT
ATTGGTGATTCAAAATGACATTGGAAATCGCTTCAGCCCGACTGCTATCGTTGCAGCCATAACAGCCCAAATACAAAAAG
CGAAATTACCGACTCACGTCGAAATTGATGCAAAGCGCTACGGCTTTGAGCGAGATTCTGTCATTCTCTTGGAGCAGATT
CGTACAATCGATAAACAAAGATTGACAGATAAAATCACACATCTTGATGATGAGATGATGGAGAAGGTTGATGAAGCCTT
ACAAGTTAGTTTGGCTCTTATTGATTTTTAA

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 14032.77 Da        Isoelectric Point: 4.4787

>AT217999 WP_005976089.1 NZ_CP084032:c1269564-1269196 [Pectobacterium colocasium]
MDEYTPKHYDIAQLRFLCENLCDESIATLGDSSHGWVNDPTSAINLQLNELIEHIATFILTFKIKYPNESELSEQVEKYL
DDTYVLFSNYGINDAELRRWQKSKAKLFGMFSGENVCTPAKT

Download         Length: 369 bp

>AT217999 NZ_CP115172:c3220544-3220263 [Bacillus safensis]
TTGTCTGAATCCAGCGCAACAAACGAAATGAAGATTCGACTACCGGAGGCTTTGATGTCTGAAATCGAACGAGTAGCAGA
GCAGGATAAGGTAACAAGAAATGAATTGATCTACCGAGCGACAAAAACGTATATTCGTGAACGTAATATTCGACAAAATC
GTGAATCGATGAGACGCGGCTACATGGAGATGGCGAAAATTAATCTGAATATCTCTTCAGAGGCACAATACGCAGAATTT
GAGGCTGAGAATACAGTTGAGCGATTAGTCAGCGGGGGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1D7Z3F0

Antitoxin

Source ID Structure
AlphaFold DB A0A1D7Z3G5

References