Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | mosAT/AbiEii-AbiEi |
| Location | 4176512..4178210 | Replicon | chromosome |
| Accession | NZ_CP084023 | ||
| Organism | Pectobacterium aroidearum strain LJ2 | ||
Toxin (Protein)
| Gene name | mosT | Uniprot ID | - |
| Locus tag | LCF43_RS18890 | Protein ID | WP_225181526.1 |
| Coordinates | 4177281..4178210 (+) | Length | 310 a.a. |
Antitoxin (Protein)
| Gene name | mosA | Uniprot ID | - |
| Locus tag | LCF43_RS18885 | Protein ID | WP_225181525.1 |
| Coordinates | 4176512..4177294 (+) | Length | 261 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LCF43_RS18840 | 4171723..4172055 | + | 333 | WP_012773213.1 | divalent cation tolerance protein CutA | - |
| LCF43_RS18845 | 4172031..4173761 | + | 1731 | WP_225181520.1 | protein-disulfide reductase DsbD | - |
| LCF43_RS18850 | 4173805..4174380 | + | 576 | WP_119871152.1 | transcriptional regulator | - |
| LCF43_RS18860 | 4174667..4174909 | - | 243 | WP_225181521.1 | helix-turn-helix transcriptional regulator | - |
| LCF43_RS18865 | 4175013..4175267 | + | 255 | WP_225181522.1 | helix-turn-helix transcriptional regulator | - |
| LCF43_RS18870 | 4175353..4175601 | + | 249 | WP_225181523.1 | helix-turn-helix transcriptional regulator | - |
| LCF43_RS18875 | 4175616..4175818 | + | 203 | Protein_3690 | type II toxin-antitoxin system antitoxin CcdA | - |
| LCF43_RS18880 | 4175978..4176358 | + | 381 | WP_225181524.1 | hypothetical protein | - |
| LCF43_RS18885 | 4176512..4177294 | + | 783 | WP_225181525.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | Antitoxin |
| LCF43_RS18890 | 4177281..4178210 | + | 930 | WP_225181526.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
| LCF43_RS18895 | 4178595..4179497 | - | 903 | WP_012773201.1 | LysR family transcriptional regulator | - |
| LCF43_RS18900 | 4179626..4179889 | + | 264 | WP_012773200.1 | DUF2798 domain-containing protein | - |
| LCF43_RS18905 | 4180055..4180828 | - | 774 | WP_225181527.1 | phosphonate metabolism protein PhnP | - |
| LCF43_RS18910 | 4180867..4181436 | - | 570 | WP_225181528.1 | ribose 1,5-bisphosphokinase | - |
| LCF43_RS18915 | 4181439..4182575 | - | 1137 | WP_180777413.1 | alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 310 a.a. Molecular weight: 35059.39 Da Isoelectric Point: 5.6727
>T217947 WP_225181526.1 NZ_CP084023:4177281-4178210 [Pectobacterium aroidearum]
MDQRDIYARQVKLLMTALPYVAKEPCFALKGGTAINLFVQDFPRLSVDIDLVYQTFIDRDTDLIAIDDALMRITESLNGR
QGITAIQQENKADEKRIIVNTADAQIKIEVSPVWRGLLLPPAEMPVCEQVEMEYGFTTMSVVSLADLYGGKICAALDRQH
PRDLFDVLNMLEKPCLTREIFDGFLCYLAGHPRPIAELLAPNWDTSRIATLYAQEFSGMTQQETSLESLLSVATLLPQAL
KSHFTAQDRQFLLSYKQNNPDWSLYRYPDIQHLPAIRWKQRNLSALHAKNPAKFSAAVGKLEKVLEQHF
MDQRDIYARQVKLLMTALPYVAKEPCFALKGGTAINLFVQDFPRLSVDIDLVYQTFIDRDTDLIAIDDALMRITESLNGR
QGITAIQQENKADEKRIIVNTADAQIKIEVSPVWRGLLLPPAEMPVCEQVEMEYGFTTMSVVSLADLYGGKICAALDRQH
PRDLFDVLNMLEKPCLTREIFDGFLCYLAGHPRPIAELLAPNWDTSRIATLYAQEFSGMTQQETSLESLLSVATLLPQAL
KSHFTAQDRQFLLSYKQNNPDWSLYRYPDIQHLPAIRWKQRNLSALHAKNPAKFSAAVGKLEKVLEQHF
Download Length: 930 bp
>T217947 NZ_CP114895:3418639-3418968 [Escherichia coli]
ATGAACACTCTACCTGCTACAATTTCGCAGGCGGCGAAGCCCTGCCTGTCGCCAGTGGCTGTCTGGCAAATGCTACTGAC
ACGCCTGCTGGAACAACACTATGGCCTGACACTGAACGACACGCCGTTCAGTGATGAAACTGTTATTAAGGAACATATCG
ATGCTGGTATCACTCTGGCCGATGCAGTCAATTTTCTGGTGGAAAAGTACGAACTGGTACGTATCGATCACAGAGGATTT
TCGTGGCAACAACAGTCTCCATATATTTCCGTAGTAGATATTCTGCGAGCAAGGCGCTCTACCGGCTTGCTAAAAACTAA
TGTGAAATAA
ATGAACACTCTACCTGCTACAATTTCGCAGGCGGCGAAGCCCTGCCTGTCGCCAGTGGCTGTCTGGCAAATGCTACTGAC
ACGCCTGCTGGAACAACACTATGGCCTGACACTGAACGACACGCCGTTCAGTGATGAAACTGTTATTAAGGAACATATCG
ATGCTGGTATCACTCTGGCCGATGCAGTCAATTTTCTGGTGGAAAAGTACGAACTGGTACGTATCGATCACAGAGGATTT
TCGTGGCAACAACAGTCTCCATATATTTCCGTAGTAGATATTCTGCGAGCAAGGCGCTCTACCGGCTTGCTAAAAACTAA
TGTGAAATAA
Antitoxin
Download Length: 261 a.a. Molecular weight: 29407.74 Da Isoelectric Point: 9.0688
>AT217947 WP_225181525.1 NZ_CP084023:4176512-4177294 [Pectobacterium aroidearum]
MTNYLNWLMQNTLPGQVLLQSWLTRNGIDRKLSYVYVQNGWLRRIAHGVYCRTGREPDWVDAVYCLQTQWEKPVRVAGLT
SLALQGYSHYTELGKPQIWLTLPAYIKLPGWFTAFKPFATFVVLYTSGLSIDVMPFTTELRIGDRRLTGSVPELAAYEIA
SGVPAQISFEHADALFQGLNLLSPRKLQALLYASHSVKTNRVMLYLAQRNGHPYFQYLDKSGIETGAGKRQIVPGGWLEP
DYQITVPREFKSEGVEDGSA
MTNYLNWLMQNTLPGQVLLQSWLTRNGIDRKLSYVYVQNGWLRRIAHGVYCRTGREPDWVDAVYCLQTQWEKPVRVAGLT
SLALQGYSHYTELGKPQIWLTLPAYIKLPGWFTAFKPFATFVVLYTSGLSIDVMPFTTELRIGDRRLTGSVPELAAYEIA
SGVPAQISFEHADALFQGLNLLSPRKLQALLYASHSVKTNRVMLYLAQRNGHPYFQYLDKSGIETGAGKRQIVPGGWLEP
DYQITVPREFKSEGVEDGSA
Download Length: 783 bp
>AT217947 NZ_CP114895:3418301-3418618 [Escherichia coli]
ATGAGCAACACCACATGGGGCCTGCAGCGAGATATCACGCCGCGCCTGGGAGCACGTCTGGTGCAGGAGGGCAACCAGCT
GCACTATCTGGCTGACCGGGCCAGTATCACCGGTAAGTTTAGTGACGCCGAATGTCCTAAGCTGGATGTGGTATTTCCAC
ATTTTATCAGCCAGATAGAGTCGATGCTGACCACTGGTGAACTGAATCCCCGCCATGCCCAATGCGTCACCCTGTACCAC
AACGGTTTTACCTGCGAAGCCGATACTCTTGGTAGTTGCGGCTACGTATACATCGCTGTTTACCCCACTCAACGCTAA
ATGAGCAACACCACATGGGGCCTGCAGCGAGATATCACGCCGCGCCTGGGAGCACGTCTGGTGCAGGAGGGCAACCAGCT
GCACTATCTGGCTGACCGGGCCAGTATCACCGGTAAGTTTAGTGACGCCGAATGTCCTAAGCTGGATGTGGTATTTCCAC
ATTTTATCAGCCAGATAGAGTCGATGCTGACCACTGGTGAACTGAATCCCCGCCATGCCCAATGCGTCACCCTGTACCAC
AACGGTTTTACCTGCGAAGCCGATACTCTTGGTAGTTGCGGCTACGTATACATCGCTGTTTACCCCACTCAACGCTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|