Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-Axe/YoeB-RelB
Location 37379..37899 Replicon plasmid unnamed1
Accession NZ_CP084013
Organism Bifidobacterium longum strain NBRC 114370

Toxin (Protein)


Gene name yoeB Uniprot ID A0A4V2N101
Locus tag LCQ81_RS10675 Protein ID WP_065436690.1
Coordinates 37645..37899 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name Axe Uniprot ID A0A4R0SSB9
Locus tag LCQ81_RS10670 Protein ID WP_065436689.1
Coordinates 37379..37645 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LCQ81_RS10650 (LCQ81_10650) 33989..34891 + 903 WP_225090437.1 colicin transporter -
LCQ81_RS10655 (LCQ81_10655) 35246..36271 + 1026 WP_225090408.1 hypothetical protein -
LCQ81_RS10660 (LCQ81_10660) 36428..36793 - 366 WP_225090409.1 hypothetical protein -
LCQ81_RS10665 (LCQ81_10665) 36816..37196 - 381 WP_065436688.1 hypothetical protein -
LCQ81_RS10670 (LCQ81_10670) 37379..37645 + 267 WP_065436689.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LCQ81_RS10675 (LCQ81_10675) 37645..37899 + 255 WP_065436690.1 Txe/YoeB family addiction module toxin Toxin
LCQ81_RS10680 (LCQ81_10680) 37936..42588 + 4653 WP_225090410.1 InlB B-repeat-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..169194 169194


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-76)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9932.40 Da        Isoelectric Point: 8.4862

>T217935 WP_065436690.1 NZ_CP084013:37645-37899 [Bifidobacterium longum]
MLLCWTEDAWADYLYWQAQDRKTLKRVNTLIRDMQRTPFEGIGKPEPLKWGLSGAWSRRIDSANRIIYTVADDRLCILSA
KDHY

Download         Length: 255 bp

>T217935 NZ_CP114895:c1861400-1861293 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9908.15 Da        Isoelectric Point: 4.3407

>AT217935 WP_065436689.1 NZ_CP084013:37379-37645 [Bifidobacterium longum]
MTQAVAYSNFRANLKTYMRKVNEDADTLLVTNADPEDNVVVMSADDYDSLMETLRVYQNPYLSDKVMRGMAQVRQGQTMA
HDLIEAGA

Download         Length: 267 bp

>AT217935 NZ_CP114895:1861448-1861514 [Escherichia coli]
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTGTACCTCTCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4V2N101

Antitoxin

Source ID Structure
AlphaFold DB A0A4R0SSB9

References