Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 11895..12697 Replicon plasmid pPRO2
Accession NC_008608
Organism Pelobacter propionicus DSM 2379

Toxin (Protein)


Gene name TacT3 Uniprot ID -
Locus tag PPRO_RS20545 Protein ID WP_011733944.1
Coordinates 11895..12422 (-) Length 176 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID A0R860
Locus tag PPRO_RS19075 Protein ID WP_011733945.1
Coordinates 12419..12697 (-) Length 93 a.a.

Genomic Context

PPRO_RS19085PPRO_RS19090PPRO_RS19095PPRO_RS19045PPRO_RS19050PPRO_RS19055PPRO_RS19060PPRO_RS19065PPRO_RS20540PPRO_RS20545PPRO_RS19075PPRO_RS19100
Location: 13713..14495 (783 bp)
Type: Others
Protein ID: WP_157040166.1
Location: 14980..15234 (255 bp)
Type: Others
Protein ID: WP_011733948.1
Location: 15218..15499 (282 bp)
Type: Others
Protein ID: WP_011733949.1
Location: 7044..7754 (711 bp)
Type: Others
Protein ID: WP_011733938.1
Location: 7756..8961 (1206 bp)
Type: Others
Protein ID: WP_011733939.1
Location: 8958..10109 (1152 bp)
Type: Others
Protein ID: WP_011733940.1
Location: 10106..10714 (609 bp)
Type: Others
Protein ID: WP_011733941.1
Location: 10973..11254 (282 bp)
Type: Others
Protein ID: WP_041533075.1
Location: 11277..11555 (279 bp)
Type: Others
Protein ID: WP_011733943.1
Location: 11895..12422 (528 bp)
Type: Toxin
Protein ID: WP_011733944.1
Location: 12419..12697 (279 bp)
Type: Antitoxin
Protein ID: WP_011733945.1
Location: 15731..16123 (393 bp)
Type: Others
Protein ID: WP_157040165.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
PPRO_RS190457044..7754-711WP_011733938.1ABC transporter ATP-binding protein-
PPRO_RS190507756..8961-1206WP_011733939.1ABC transporter permease-
PPRO_RS190558958..10109-1152WP_011733940.1efflux RND transporter periplasmic adaptor subunit-
PPRO_RS1906010106..10714-609WP_011733941.1TetR/AcrR family transcriptional regulator-
PPRO_RS1906510973..11254-282WP_041533075.1HigA family addiction module antidote protein-
PPRO_RS2054011277..11555-279WP_011733943.1type II toxin-antitoxin system RelE/ParE family toxin-
PPRO_RS2054511895..12422-528WP_011733944.1GNAT family N-acetyltransferaseToxin
PPRO_RS1907512419..12697-279WP_011733945.1DUF1778 domain-containing proteinAntitoxin
PPRO_RS1908513713..14495+783WP_157040166.1pirin-
PPRO_RS1909014980..15234+255WP_011733948.1ribbon-helix-helix domain-containing protein-
PPRO_RS1909515218..15499+282WP_011733949.1type II toxin-antitoxin system RelE/ParE family toxin-
PPRO_RS1910015731..16123-393WP_157040165.1hypothetical protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..3072230722


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(11-86)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 19085.83 Da        Isoelectric Point: 8.7489

>T21793 WP_011733944.1 NC_008608:c12422-11895 [Pelobacter propionicus DSM 2379]
MTISPWHEEPISKQHNREAFDCGNAALNDFLRRHARQTHEHGGAKTFVAVSDDNPSLVFGFYSLSPASVEFSRTPSIITR
GLARHDVPVFRLCRLAVDRTMQSKGLGGQLLLSAGRRCLRASQEVGGVALLIDAKNESVAHWYTNYGALPLLDIPLSLLL
PLSTIQAALNAAGKL

Download         Length: 528 bp

>T21793 NC_008608:c12422-11895 [Pelobacter propionicus DSM 2379]
ATGACGATTTCCCCTTGGCATGAAGAGCCGATTTCCAAACAGCATAACCGAGAAGCATTTGATTGCGGCAATGCCGCATT
AAATGATTTCCTACGCCGACATGCACGACAAACGCACGAACACGGGGGCGCTAAAACCTTCGTGGCAGTCAGTGATGATA
ATCCGTCATTGGTTTTTGGCTTCTATTCTCTTAGTCCCGCCTCTGTTGAGTTTTCCCGTACTCCCTCTATCATCACGCGC
GGATTGGCTCGGCATGACGTGCCTGTCTTCCGCCTTTGTCGTCTGGCGGTTGATCGGACTATGCAAAGCAAGGGGCTGGG
TGGTCAACTTCTTCTGTCCGCCGGTAGGCGCTGCCTTCGCGCCTCGCAAGAGGTCGGAGGCGTGGCATTATTGATCGACG
CCAAGAACGAGAGCGTCGCGCATTGGTACACCAATTATGGCGCTTTGCCTCTTCTAGATATACCGCTTTCTCTGCTTCTG
CCGCTATCGACCATCCAAGCGGCGTTAAACGCTGCCGGAAAACTATAG

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10141.71 Da        Isoelectric Point: 9.9233

>AT21793 WP_011733945.1 NC_008608:c12697-12419 [Pelobacter propionicus DSM 2379]
MPRVAVKENNRMSLRIRPNDKALLMRAVSYTHTDLTDFVLKNALQAAKDVIAQAEQVSLSERDSLRVLDALENPPSPNSK
LLAAAHALPVQP

Download         Length: 279 bp

>AT21793 NC_008608:c12697-12419 [Pelobacter propionicus DSM 2379]
ATGCCAAGAGTGGCCGTAAAAGAGAACAATCGAATGTCTTTGAGAATCCGCCCGAATGATAAGGCGCTGCTGATGCGTGC
CGTTTCCTATACGCATACCGACCTTACGGATTTTGTACTGAAAAACGCCTTGCAAGCGGCAAAGGATGTGATCGCCCAGG
CTGAACAGGTTTCACTGTCAGAGCGCGACAGCTTGCGTGTATTGGATGCTTTGGAAAATCCGCCTTCTCCGAATTCAAAA
CTGCTGGCGGCGGCTCATGCCTTGCCTGTGCAGCCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0R860

References