Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yjhX-yjhQ/YjhX-GNAT |
Location | 3949644..3950458 | Replicon | chromosome |
Accession | NZ_CP083990 | ||
Organism | Escherichia coli strain EC2648-Vir2 |
Toxin (Protein)
Gene name | yjhX | Uniprot ID | S1PA82 |
Locus tag | LCH23_RS19245 | Protein ID | WP_001054376.1 |
Coordinates | 3949644..3949901 (+) | Length | 86 a.a. |
Antitoxin (Protein)
Gene name | yjhQ | Uniprot ID | U9Z4B8 |
Locus tag | LCH23_RS19250 | Protein ID | WP_001309181.1 |
Coordinates | 3949913..3950458 (+) | Length | 182 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LCH23_RS19220 (3944932) | 3944932..3946038 | + | 1107 | WP_001309184.1 | N-acetylneuraminate epimerase | - |
LCH23_RS19225 (3946103) | 3946103..3947083 | + | 981 | WP_000991438.1 | 9-O-acetyl-N-acetylneuraminic acid deacetylase | - |
LCH23_RS19230 (3947193) | 3947193..3947398 | + | 206 | Protein_3779 | HNH endonuclease | - |
LCH23_RS19235 (3947666) | 3947666..3948906 | - | 1241 | Protein_3780 | helicase YjhR | - |
LCH23_RS19240 (3949022) | 3949022..3949153 | + | 132 | WP_001309182.1 | hypothetical protein | - |
LCH23_RS19245 (3949644) | 3949644..3949901 | + | 258 | WP_001054376.1 | YjhX family toxin | Toxin |
LCH23_RS19250 (3949913) | 3949913..3950458 | + | 546 | WP_001309181.1 | N-acetyltransferase | Antitoxin |
LCH23_RS19255 (3950514) | 3950514..3951260 | + | 747 | WP_000354251.1 | class I SAM-dependent methyltransferase | - |
LCH23_RS19260 (3951429) | 3951429..3951647 | + | 219 | Protein_3785 | hypothetical protein | - |
LCH23_RS19265 (3951685) | 3951685..3951801 | + | 117 | Protein_3786 | VOC family protein | - |
LCH23_RS19270 (3952046) | 3952046..3953167 | + | 1122 | WP_000010829.1 | M42 family metallopeptidase | - |
LCH23_RS19275 (3953164) | 3953164..3953442 | + | 279 | WP_000722973.1 | PTS sugar transporter subunit IIB SgcB | - |
LCH23_RS19280 (3953454) | 3953454..3954767 | + | 1314 | WP_000460843.1 | PTS sugar transporter subunit IIC SgcC | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | fimI / fimA / fimE / fimB | 3938654..3958682 | 20028 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 86 a.a. Molecular weight: 9734.29 Da Isoelectric Point: 11.0090
>T217903 WP_001054376.1 NZ_CP083990:3949644-3949901 [Escherichia coli]
MNLSRQEQHTLHVLAKGRRIAHVRDSSGRVTSVECYSREGLLLTDCTLAVFKKLKTKKLIKSVNGQPYRINTTELNKVRA
QLDNR
MNLSRQEQHTLHVLAKGRRIAHVRDSSGRVTSVECYSREGLLLTDCTLAVFKKLKTKKLIKSVNGQPYRINTTELNKVRA
QLDNR
Download Length: 258 bp
>T217903 NZ_CP114894:c573164-573057 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCGGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCGGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA
Antitoxin
Download Length: 182 a.a. Molecular weight: 19956.90 Da Isoelectric Point: 6.3277
>AT217903 WP_001309181.1 NZ_CP083990:3949913-3950458 [Escherichia coli]
MTVHHFTFHITDKSDASDIREVETRAFGFSKEADLVASLLEDESARPALSLLARYEGKAVGHILFTRATFKGEMDSPLMH
ILAPLAVIPEYQGMGVGGRLIRTGIEHLRLMGCQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMMQSLTA
QPMTLTGHIRCADPDETGALT
MTVHHFTFHITDKSDASDIREVETRAFGFSKEADLVASLLEDESARPALSLLARYEGKAVGHILFTRATFKGEMDSPLMH
ILAPLAVIPEYQGMGVGGRLIRTGIEHLRLMGCQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMMQSLTA
QPMTLTGHIRCADPDETGALT
Download Length: 546 bp
>AT217903 NZ_CP114894:573211-573277 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT
TGTCTGGTTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|