Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) slvAT/RES(toxin)
Location 46059..46975 Replicon plasmid pB1-1-8
Accession NZ_CP083957
Organism Mesorhizobium sp. B1-1-8

Toxin (Protein)


Gene name slvT Uniprot ID -
Locus tag FJ974_RS27900 Protein ID WP_140533556.1
Coordinates 46059..46592 (-) Length 178 a.a.

Antitoxin (Protein)


Gene name slvA Uniprot ID -
Locus tag FJ974_RS27905 Protein ID WP_140533557.1
Coordinates 46589..46975 (-) Length 129 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FJ974_RS27875 (FJ974_27875) 42115..43221 - 1107 WP_140533551.1 site-specific integrase -
FJ974_RS27880 (FJ974_27880) 43321..43599 + 279 WP_140533552.1 DUF1778 domain-containing protein -
FJ974_RS27885 (FJ974_27885) 43596..44123 + 528 WP_140533553.1 GNAT family N-acetyltransferase -
FJ974_RS27890 (FJ974_27890) 44370..45323 + 954 WP_140533554.1 DUF1403 family protein -
FJ974_RS27895 (FJ974_27895) 45326..46024 + 699 WP_140533555.1 SMC-Scp complex subunit ScpB -
FJ974_RS27900 (FJ974_27900) 46059..46592 - 534 WP_140533556.1 RES family NAD+ phosphorylase Toxin
FJ974_RS27905 (FJ974_27905) 46589..46975 - 387 WP_140533557.1 DUF2384 domain-containing protein Antitoxin
FJ974_RS27910 (FJ974_27910) 47066..47377 - 312 WP_226891697.1 hypothetical protein -
FJ974_RS27915 (FJ974_27915) 47609..49228 + 1620 WP_140533558.1 hypothetical protein -
FJ974_RS27920 (FJ974_27920) 49188..49538 + 351 WP_140533559.1 hypothetical protein -
FJ974_RS27925 (FJ974_27925) 49573..49986 + 414 WP_181177136.1 hypothetical protein -
FJ974_RS27930 (FJ974_27930) 50013..50333 + 321 WP_226891698.1 hypothetical protein -
FJ974_RS27935 (FJ974_27935) 50413..50610 - 198 WP_181177133.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..494404 494404


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(12-167)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 178 a.a.        Molecular weight: 19512.21 Da        Isoelectric Point: 7.1292

>T217871 WP_140533556.1 NZ_CP083957:c46592-46059 [Mesorhizobium sp. B1-1-8]
VKVTRVGPDEIFHRYLTPKWAFLPTSGAGAAIDGGRFNRPGVEALYLSRAPQTALEEYKQGASIVPPATLAAYKITLAEV
ADLSQGFDPDIWDGAWREWDCAWRKIARIDKKIPPSWKLADMVITAGLRGILFPSLRHAGGTNLVIFPANLVDGDHVAVH
DPDHRLPHDQSSWSLSH

Download         Length: 534 bp

>T217871 NZ_CP114892:3585514-3585687 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin


Download         Length: 129 a.a.        Molecular weight: 14073.99 Da        Isoelectric Point: 8.5038

>AT217871 WP_140533557.1 NZ_CP083957:c46975-46589 [Mesorhizobium sp. B1-1-8]
MAQAQLVHSTVISGFVDSLQEPRTPYISPKRLSQALGVKVANLAQLTGVHRNTLRNPSSERLQGRMREMVKVISAATELT
GDVDKAIYWYRNEPIADYGHRTAAELVADGQVEAVLAFIRDLENGARG

Download         Length: 387 bp

>AT217871 NZ_CP114892:3585190-3585486 [Escherichia coli]
ATGGAAGGTAAAAACAAGTTCAATACTTATGTTGTTTCTTTTGATTATCCATCATCTTATTCCTCAGTGTTCTTAAGATT
AAGATCATTGATGTATGATATGAATTTCTCCTCTATCGTGGCTGATGAATATGGGATACCACGACAATTGAATGAAAACT
CCTTCGCAATAACGACATCGTTAGCCGCAAGTGAAATCGAAGATTTAATCAGGCTCAAATGCTTAGACTTACCGGATATT
GATTTTGACCTCAACATTATGACAGTTGATGACTATTTCCGTCAGTTTTACAAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References