Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 5647560..5649069 Replicon chromosome
Accession NZ_CP083954
Organism Mesorhizobium sp. B2-1-1

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag FJ972_RS27380 Protein ID WP_140523977.1
Coordinates 5648170..5649069 (+) Length 300 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag FJ972_RS27375 Protein ID WP_140523979.1
Coordinates 5647560..5648180 (+) Length 207 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FJ972_RS27355 (FJ972_27355) 5643172..5645064 + 1893 WP_140523985.1 acyltransferase family protein -
FJ972_RS27365 (FJ972_27365) 5645326..5646252 - 927 WP_140523983.1 site-specific integrase -
FJ972_RS27370 (FJ972_27370) 5646966..5647376 - 411 WP_140523981.1 helix-turn-helix transcriptional regulator -
FJ972_RS27375 (FJ972_27375) 5647560..5648180 + 621 WP_140523979.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
FJ972_RS27380 (FJ972_27380) 5648170..5649069 + 900 WP_140523977.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
FJ972_RS27385 (FJ972_27385) 5649466..5649831 + 366 WP_140624801.1 hypothetical protein -
FJ972_RS27390 (FJ972_27390) 5649809..5650798 - 990 WP_140496609.1 LysR family transcriptional regulator -
FJ972_RS27395 (FJ972_27395) 5651088..5652158 + 1071 WP_140496611.1 sugar ABC transporter substrate-binding protein -
FJ972_RS27400 (FJ972_27400) 5652257..5653789 + 1533 WP_140496613.1 sugar ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(38-260)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(15-55)


Sequences

Toxin        


Download         Length: 300 a.a.        Molecular weight: 33147.94 Da        Isoelectric Point: 5.5537

>T217861 WP_140523977.1 NZ_CP083954:5648170-5649069 [Mesorhizobium sp. B2-1-1]
MARELRNVGASVRARLLDRAREERADFQLLLTRYALERLLYRLSISTERERFLLKGAMLFAAWLDNPFRPTRDLDLLGSG
DAGVATMVECFRAICSTPVEDDGVEFDVAGLTAEPIRNDAEYAGVRVRTAATIAGARVPIQVDVGFGDVVTPAPVDLEYP
TLLDSPPPRLRAYPPETVVAEKFEALARLGVANSRMKDFYDLWMIARTFSFEGSVLSSAIRRTFERRQTAWPTEIPTGLS
VAFAAAKSGQWRAFLTRERMAAAPGDFTTIIDGLRVFLAPLLTEGPHTGRWPPGGPWTE

Download         Length: 900 bp

>T217861 NZ_CP114892:c1307601-1307347 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGACGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin


Download         Length: 207 a.a.        Molecular weight: 23030.81 Da        Isoelectric Point: 10.3856

>AT217861 WP_140523979.1 NZ_CP083954:5647560-5648180 [Mesorhizobium sp. B2-1-1]
MSHKPTQRDQARALLLDGSLVRLRDLTGAGVSPETMARLVREGEVVRLARGLYQLAEAMPDARRSIAEASALVPKGVVCL
TSALQFHDLTLQMPSAIWMAIDRTGWKPKVDYPPIRFVRFSGHALTEGIKRHRIEGIDVPVFEPAKAIVDCFRYRNKIGL
DIAIEGLREGLRTRQVTPDQLWKFAQSGRVWSVMRPYVEAMVANGA

Download         Length: 621 bp

>AT217861 NZ_CP114892:c1307849-1307598 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGCTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATCATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References