Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) slvAT/RES(toxin)
Location 174599..175500 Replicon plasmid pB2-1-8
Accession NZ_CP083953
Organism Mesorhizobium sp. B2-1-8

Toxin (Protein)


Gene name slvT Uniprot ID -
Locus tag FJ970_RS31995 Protein ID WP_140762495.1
Coordinates 174599..175123 (-) Length 175 a.a.

Antitoxin (Protein)


Gene name slvA Uniprot ID -
Locus tag FJ970_RS32000 Protein ID WP_140762493.1
Coordinates 175120..175500 (-) Length 127 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FJ970_RS31965 (FJ970_31965) 169861..170373 + 513 WP_140762506.1 RES family NAD+ phosphorylase -
FJ970_RS31970 (FJ970_31970) 170682..170915 + 234 WP_140762504.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
FJ970_RS31975 (FJ970_31975) 170912..171316 + 405 WP_140762502.1 type II toxin-antitoxin system VapC family toxin -
FJ970_RS31980 (FJ970_31980) 171374..172627 - 1254 WP_181178739.1 site-specific integrase -
FJ970_RS31985 (FJ970_31985) 172903..173856 + 954 WP_140762499.1 DUF1403 family protein -
FJ970_RS31990 (FJ970_31990) 173859..174557 + 699 WP_140762497.1 SMC-Scp complex subunit ScpB -
FJ970_RS31995 (FJ970_31995) 174599..175123 - 525 WP_140762495.1 RES family NAD+ phosphorylase Toxin
FJ970_RS32000 (FJ970_32000) 175120..175500 - 381 WP_140762493.1 DUF2384 domain-containing protein Antitoxin
FJ970_RS32005 (FJ970_32005) 175787..176509 - 723 WP_140762491.1 toll/interleukin-1 receptor domain-containing protein -
FJ970_RS32010 (FJ970_32010) 177294..178103 - 810 WP_140762489.1 hypothetical protein -
FJ970_RS32015 (FJ970_32015) 178103..178348 - 246 WP_140762487.1 hypothetical protein -
FJ970_RS32020 (FJ970_32020) 178656..179351 + 696 WP_140762485.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..494461 494461


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(12-167)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 175 a.a.        Molecular weight: 19272.67 Da        Isoelectric Point: 5.9087

>T217856 WP_140762495.1 NZ_CP083953:c175123-174599 [Mesorhizobium sp. B2-1-8]
VKVTRVGPDEIFHRYLTPKWAFLPTSGAGAAIDGGRFNRPGVEALYLSRSPQTALDEYRQGASIVPPATLAAYKITLAEV
ADLSQGFDPDVWDDAWQEWDCAWRHIARIDKKMPPSWKLADTVITTGLRGILFPSLRHAGGTNLVVFSANLVDGDHVEVH
DPDHRLPQDQSSWS

Download         Length: 525 bp

>T217856 NZ_CP114892:728266-728442 [Escherichia coli]
GTGAAACAAAGCGAGTTCAGACGTTGGCTCGAATCTCAGGGCGTCGATGTAGCGAATGGCAGCAACCATTTGAAACTCAG
GTTTCATGGGAGGCGCAGTGTCATGCCGCGTCACCCCTGCGATGAGATTAAAGAACCATTGCGTAAAGCAATCCTGAAAC
AACTCGGTTTGAGTTAA

Antitoxin


Download         Length: 127 a.a.        Molecular weight: 13834.67 Da        Isoelectric Point: 7.3173

>AT217856 WP_140762493.1 NZ_CP083953:c175500-175120 [Mesorhizobium sp. B2-1-8]
MTHAAPSTVISGFVDSLQEPRTPYISPKRLSEALGVKVANLAQLTGVHRNTLRNPSSERLQGRMREMVKVISAATELTGD
VDKAIYWYRNEPIADYGHRTAAELVADSQVEAVLAFIRDLENGARG

Download         Length: 381 bp

>AT217856 NZ_CP114892:728488-728904 [Escherichia coli]
ATGCGTTATCCCGTCACTCTTACACCCGCGCCGGAAGGCGGTTATATGGTTTCTTTTGTGGATATCCCTGAAGCGTTGAC
CCAGGGCGAAACTGTCGCTGAAGCGATGGAAGCGGCAAAAGATGCTTTACTGACCGCATTTGATTTTTATTTTGAAGATA
ACGAGCTTATCCCTTTACCTTCGCCATTAAATAGTCACGATCACTTTATTGAAGTACCTTTGAGCGTCGCCTCTAAGGTA
TTGCTGTTAAATGCTTTTTTACAGTCAGAAATCACTCAGCAAGAGTTAGCCAGGCGAATTGGCAAACCTAAACAGGAGAT
TACTCGCCTATTTAACTTGCATCATGCGACAAAAATCGACGCCGTCCAGCTCGCGGCAAAGGCGCTTGGCAAAGAGTTAT
CGCTGGTGATGGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References