Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 3014333..3015090 Replicon chromosome
Accession NZ_CP083952
Organism Mesorhizobium sp. B2-1-8

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag FJ970_RS14840 Protein ID WP_140759067.1
Coordinates 3014614..3015090 (+) Length 159 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag FJ970_RS14835 Protein ID WP_140759069.1
Coordinates 3014333..3014614 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FJ970_RS14810 (FJ970_14810) 3009706..3010692 + 987 WP_140759079.1 ABC transporter permease -
FJ970_RS14815 (FJ970_14815) 3010695..3011243 + 549 WP_140759077.1 gluconokinase -
FJ970_RS14820 (FJ970_14820) 3011238..3012389 - 1152 WP_140759075.1 hypothetical protein -
FJ970_RS14825 (FJ970_14825) 3012400..3012849 - 450 WP_140759073.1 Rrf2 family transcriptional regulator -
FJ970_RS14830 (FJ970_14830) 3013102..3014088 - 987 WP_140759071.1 sulfate ABC transporter substrate-binding protein -
FJ970_RS14835 (FJ970_14835) 3014333..3014614 + 282 WP_140759069.1 DUF1778 domain-containing protein Antitoxin
FJ970_RS14840 (FJ970_14840) 3014614..3015090 + 477 WP_140759067.1 GNAT family N-acetyltransferase Toxin
FJ970_RS14845 (FJ970_14845) 3015157..3016197 - 1041 WP_140759065.1 sulfate/molybdate ABC transporter ATP-binding protein -
FJ970_RS14850 (FJ970_14850) 3016210..3017094 - 885 WP_140759063.1 sulfate ABC transporter permease subunit CysW -
FJ970_RS14855 (FJ970_14855) 3017087..3017938 - 852 WP_140759061.1 sulfate ABC transporter permease subunit CysT -
FJ970_RS14860 (FJ970_14860) 3017962..3018990 - 1029 WP_140759060.1 sulfate ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(32-144)

Antitoxin

Vibrio phage ICP1, Orf50

(14-77)


Sequences

Toxin        


Download         Length: 159 a.a.        Molecular weight: 17095.64 Da        Isoelectric Point: 8.0411

>T217852 WP_140759067.1 NZ_CP083952:3014614-3015090 [Mesorhizobium sp. B2-1-8]
MPSAPTPLAEDHDLELFQSGTESLDQWLRRRARANQVSGASRTYVMAEGTRVVGYYCLSSGGLDLAEAPGIIRRNMPDPI
PMVVLGRLAVDASWQGKGLGAALLQDAVLRSSQAATILRIRGIFVHAISDEAKAFYEHYGFAASPKNPMILLLSLKGQ

Download         Length: 477 bp

>T217852 NZ_CP114892:c439099-438992 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10717.29 Da        Isoelectric Point: 7.2031

>AT217852 WP_140759069.1 NZ_CP083952:3014333-3014614 [Mesorhizobium sp. B2-1-8]
MAKAAPETHAKPVNLRIREDVRILIDRAAKIRGKTRSDFMIDVAYRAAEDTLLDQTLIKVDPESYRHYLDILDEPPSGEG
FARLMNVPRPWRD

Download         Length: 282 bp

>AT217852 NZ_CP114892:439147-439213 [Escherichia coli]
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTGTACCTCTCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References