Detailed information of TA system TA217848

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tacAT/DUF1778(antitoxin)
• Location: 347889..348691
• Replicon: chromosome
• Accession: NZ_CP083952
• Organism: Mesorhizobium sp. B2-1-8

Toxin (Protein)

• Gene name: TacT3
• Uniprot ID: -
• Locus tag: FJ970_RS01595
• Protein ID: WP_140757123.1
• Coordinates: 348164..348691 (+)
• Length: 176 a.a.

Antitoxin (Protein)

• Gene name: TacA3
• Uniprot ID: -
• Locus tag: FJ970_RS01590
• Protein ID: WP_140757121.1
• Coordinates: 347889..348167 (+)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FJ970_RS01565 (FJ970_01565)	343329..344522	+	1194	WP_227792142.1	MFS transporter	-
FJ970_RS01570 (FJ970_01570)	344539..344946	-	408	WP_140757422.1	DUF2000 family protein	-
FJ970_RS01575 (FJ970_01575)	345000..345869	+	870	WP_140757115.1	AraC family transcriptional regulator	-
FJ970_RS01580 (FJ970_01580)	345882..346352	-	471	WP_140757117.1	MarR family transcriptional regulator	-
FJ970_RS01585 (FJ970_01585)	346753..347808	+	1056	WP_140757119.1	GTP-binding protein	-
FJ970_RS01590 (FJ970_01590)	347889..348167	+	279	WP_140757121.1	DUF1778 domain-containing protein	Antitoxin
FJ970_RS01595 (FJ970_01595)	348164..348691	+	528	WP_140757123.1	GNAT family N-acetyltransferase	Toxin
FJ970_RS01600 (FJ970_01600)	348786..349760	+	975	WP_140757125.1	WD40 repeat domain-containing protein	-
FJ970_RS01605 (FJ970_01605)	349774..350226	-	453	WP_140757127.1	hypothetical protein	-
FJ970_RS01610 (FJ970_01610)	350379..351755	+	1377	WP_140757129.1	aspartate aminotransferase family protein	-
FJ970_RS01615 (FJ970_01615)	351788..353173	+	1386	WP_181178392.1	glutamine synthetase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Vibrio phage ICP1, Orf50 (4-88)

Sequences

Toxin

Protein

• Length: 176 a.a.
• Molecular weight: 19045.83 Da
• Isoelectric Point: 8.7434

>T217848 WP_140757123.1 NZ_CP083952:348164-348691 [Mesorhizobium sp. B2-1-8]
VTLPAWHEEPIAKRHDRASFDCGDAQMNDFLRRFARQSHEQNAAKTFCAIDDAALDRILGFYTIAPSAIAHETVPETMTR
GLARHEVSGFKLARLATDRSVARQGLGGQLLAAAALRCLRLAGEGGGILLIIDAKSERAARWYASYGAERLQGSNLILVM
PLATFATDLRAKGLL

Nucleotide

• Length: 528 bp

>T217848 NZ_CP114891:3400355-3400612 [Escherichia coli]
ATGAATTTATCCCGTCAGGAACAACATACCTTACACGTTCTCGCTAAAGGTAGACGTATTGCGCACGTCCGCGATTCTTC
AGGCCGCGTCACTTCCGTTGAATGCTACAGCCGCGAAGGGCTGTTGCTGACCGACTGCACGCTCGCCGTCTTCAAAAAAC
TCAAAACCAAAAAACTTATCAAGTCCGTCAATGGCCAGCCCTATCGAATCAACACCACCGAGCTGAATAAAGTTCGCGCT
CAGCTCGATAATCGCTAA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10061.64 Da
• Isoelectric Point: 8.6379

>AT217848 WP_140757121.1 NZ_CP083952:347889-348167 [Mesorhizobium sp. B2-1-8]
MPRSADTKTERYQIRIAPAQKAMIARAAALSHQDVTDFILNKVVPEAQAVIEAAEVAKVSDRDFTRILDLLENPPKPNAK
LRAAIAALPDTL

Nucleotide

• Length: 279 bp

>AT217848 NZ_CP114891:3400624-3401169 [Escherichia coli]
ATGACAGTACACCACTTCACTTTTCATATCACAGATAAAAGTGATGCCAGTGATATCCGGGAAGTCGAAACCCGCGCATT
TGGCTTCAGCAAAGAAGCCGATTTAGTGGCCTCTTTACTTGAGGATGAAAGCGCGCGCCCCGCGTTATCGCTGCTAGCCC
GGTATGAAGGCAAAGCCGTCGGGCATATTTTATTTACCCGGGCAACCTTCAAAGGAGAAATGGATTCACCGTTGATGCAC
ATCCTCGCTCCCCTGGCGGTCATACCGGAATACCAAGGGATGGGCGTGGGAGGACGGTTGATACGCACTGGCATCGAGCA
CCTGAGGTTGATGGGCTGCCAGACGGTTTTTGTTCTCGGCCACGCCACCTATTACCCCCGACATGGGTTCGAACCCTGTG
CCGGAGACAAAGGCTATCCGGCACCTTATCCCATCCCGGAGGAGCACAAAGCCTGCTGGATGATGCAATCACTCACCGCT
CAGCCCATGACCCTGACCGGCCACATCCGGTGCGCAGACCCTGATGAAACCGGAGCACTGACGTGA