Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 4698438..4699093 Replicon chromosome
Accession NZ_CP083950
Organism Mesorhizobium sp. B4-1-4

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FJW03_RS22610 Protein ID WP_140766906.1
Coordinates 4698692..4699093 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FJW03_RS22605 Protein ID WP_140766907.1
Coordinates 4698438..4698692 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FJW03_RS22590 (FJW03_22590) 4694346..4694924 - 579 WP_140697899.1 LPS assembly lipoprotein LptE -
FJW03_RS22595 (FJW03_22595) 4694911..4697535 - 2625 WP_140766909.1 leucine--tRNA ligase -
FJW03_RS22600 (FJW03_22600) 4697685..4698347 + 663 WP_140766908.1 YggS family pyridoxal phosphate-dependent enzyme -
FJW03_RS22605 (FJW03_22605) 4698438..4698692 + 255 WP_140766907.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
FJW03_RS22610 (FJW03_22610) 4698692..4699093 + 402 WP_140766906.1 type II toxin-antitoxin system VapC family toxin Toxin
FJW03_RS22615 (FJW03_22615) 4699217..4700266 + 1050 WP_140766905.1 aldo/keto reductase -
FJW03_RS22620 (FJW03_22620) 4700315..4701223 - 909 WP_140612210.1 LysR family transcriptional regulator -
FJW03_RS22625 (FJW03_22625) 4701349..4702530 + 1182 WP_140766904.1 MFS transporter -
FJW03_RS22630 (FJW03_22630) 4702588..4703621 + 1034 Protein_4485 aldo/keto reductase -
FJW03_RS22635 (FJW03_22635) 4703815..4704087 - 273 WP_140697878.1 usg protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-116)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-54)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14821.00 Da        Isoelectric Point: 5.2342

>T217842 WP_140766906.1 NZ_CP083950:4698692-4699093 [Mesorhizobium sp. B4-1-4]
MYLLDTNVVSDVERRLPKPTAWLASVDPSSVNLSVITLGEIERGIVRLRKIDSEKATRLDLWLRELRRDNADRILAVTDD
VALAWGRITAGRTRGSADTLIAATALVHNLVMVTRNVADFEETGVTVLNPWEI

Download         Length: 402 bp

>T217842 NZ_CP114891:2145818-2145925 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9652.80 Da        Isoelectric Point: 5.1409

>AT217842 WP_140766907.1 NZ_CP083950:4698438-4698692 [Mesorhizobium sp. B4-1-4]
MNWHLQDAKNNFSKVVQRARSEGPQTVTLRGERAAVVLSAEDYDRLAGKKKSLAEYLLTGPVWDDDFAEEVNRRPETMIR
DVDF

Download         Length: 255 bp

>AT217842 NZ_CP114891:c2145771-2145705 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References