Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 1584408..1584915 Replicon chromosome
Accession NZ_CP083931
Organism Alysiella filiformis DSM 16848

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag JF568_RS07725 Protein ID WP_097113728.1
Coordinates 1584408..1584674 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag JF568_RS07730 Protein ID WP_097113727.1
Coordinates 1584661..1584915 (+) Length 85 a.a.

Genomic Context

JF568_RS07715JF568_RS07720JF568_RS07725JF568_RS07730JF568_RS07735JF568_RS07740JF568_RS07745JF568_RS07750JF568_RS07755JF568_RS07760JF568_RS07765JF568_RS07705JF568_RS07710
Location: 1583187..1583714 (528 bp)
Type: Others
Protein ID: WP_097113826.1
Location: 1583719..1584321 (603 bp)
Type: Others
Protein ID: WP_097113729.1
Location: 1584408..1584674 (267 bp)
Type: Toxin
Protein ID: WP_097113728.1
Location: 1584661..1584915 (255 bp)
Type: Antitoxin
Protein ID: WP_097113727.1
Location: 1584929..1585402 (474 bp)
Type: Others
Protein ID: WP_097113726.1
Location: 1585432..1585878 (447 bp)
Type: Others
Protein ID: WP_143269103.1
Location: 1585973..1586254 (282 bp)
Type: Others
Protein ID: WP_097113825.1
Location: 1586241..1586537 (297 bp)
Type: Others
Protein ID: WP_097113724.1
Location: 1586685..1587359 (675 bp)
Type: Others
Protein ID: WP_097113723.1
Location: 1587843..1588451 (609 bp)
Type: Others
Protein ID: WP_097113721.1
Location: 1588533..1589588 (1056 bp)
Type: Others
Protein ID: WP_097113720.1
Location: 1582103..1582768 (666 bp)
Type: Others
Protein ID: WP_097113732.1
Location: 1582761..1582949 (189 bp)
Type: Others
Protein ID: WP_097113731.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
JF568_RS07705 (JF568_07705)1582103..1582768-666WP_097113732.17-cyano-7-deazaguanine synthase QueC-
JF568_RS07710 (JF568_07710)1582761..1582949-189WP_097113731.1NF038104 family lipoprotein-
JF568_RS07715 (JF568_07715)1583187..1583714+528WP_097113826.1disulfide bond formation protein B-
JF568_RS07720 (JF568_07720)1583719..1584321+603WP_097113729.1nicotinate (nicotinamide) nucleotide adenylyltransferase-
JF568_RS07725 (JF568_07725)1584408..1584674+267WP_097113728.1BrnT family toxinToxin
JF568_RS07730 (JF568_07730)1584661..1584915+255WP_097113727.1CopG family antitoxinAntitoxin
JF568_RS07735 (JF568_07735)1584929..1585402+474WP_097113726.1preQ(1) synthase-
JF568_RS07740 (JF568_07740)1585432..1585878+447WP_143269103.1hypothetical protein-
JF568_RS07745 (JF568_07745)1585973..1586254+282WP_097113825.1BrnT family toxin-
JF568_RS07750 (JF568_07750)1586241..1586537+297WP_097113724.1BrnA antitoxin family protein-
JF568_RS07755 (JF568_07755)1586685..1587359+675WP_097113723.17-cyano-7-deazaguanine/7-aminomethyl-7- deazaguanine transporter-
JF568_RS07760 (JF568_07760)1587843..1588451+609WP_097113721.1DUF4230 domain-containing protein-
JF568_RS07765 (JF568_07765)1588533..1589588+1056WP_097113720.1metallophosphoesterase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideProphage--1561611..158653724926


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(6-81)

Antitoxin

CopG antitoxin

(16-75)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10519.91 Da        Isoelectric Point: 7.5211

>T217806 WP_097113728.1 NZ_CP083931:1584408-1584674 [Alysiella filiformis DSM 16848]
MFEFEYDPNKSQSNHTKHGIDFETAQYLWQDPQLLSIPIQTEPEIRHLAIGIIGEKHWSAIYTHRNGKIRLISVRRSRDK
EKMLYETH

Download         Length: 267 bp

>T217806 NZ_CP114853:c5255091-5254708 [Klebsiella pneumoniae]
ATGACCTCCGGATCTGCGCTTTTTGATACCAATATTCTTATTGATTTATTTAGCGGGCGTCGCGAAGCCAAACAGGCGCT
GGAGGCCTGGCCACCGCAGAATGCGATCAGTCTGATTACCTGGATGGAGGTGATGGTTGGCGCTAAAAAATATCACCAGG
AGCAGCGCACGCGAATGGCGCTGAGCACCTTTAATATCATTAACATCTCACAGGATATTGCAGAGCGAAGCGTTGCGCTG
CGGCAGGAGTATAAGCTTAAGCTGCCGGATGCCATCATTCTGGCGACGGCGCAACTCCATCGTCTGGAACTAATTACGCG
GAATACGAAGGATTTTGCCGGTATTCCTGGCGTAGTCACGCCGTACGAAATCCACCCTGAATAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9904.28 Da        Isoelectric Point: 5.0623

>AT217806 WP_097113727.1 NZ_CP083931:1584661-1584915 [Alysiella filiformis DSM 16848]
MKPIDTEVFERKFDDNQEDILEYLDLSQATRVHQNKIATRRVNVDFPLWMLESLDREAANLGVARQALIKMWLSQHLPPN
QQNI

Download         Length: 255 bp

>AT217806 NZ_CP114853:c5255333-5255091 [Klebsiella pneumoniae]
ATGATGGCTGAAAGGGATATGGGCAGAATTCTTCTCGATTTATCAGACGATGTCATTCAACGTCTCGATGACCTCAAAGT
GCAGCGTAACATTCCGCGAGCGGAACTGTTACGTGAAGCGGTTGAACAATATCTGGAGAAACAAGATCGAGCTAAAGATA
CCATCTCCAGTGCGCTGGGTCTGTGGCAAGACTGCGAAGAAGACGGCATGGAATATCAACGTCAGCTACGCAAGGAGTGG
TAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
No matching records found

References