Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 427337..427848 Replicon chromosome
Accession NZ_CP083931
Organism Alysiella filiformis DSM 16848

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag JF568_RS02160 Protein ID WP_097113562.1
Coordinates 427588..427848 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag JF568_RS02155 Protein ID WP_097113561.1
Coordinates 427337..427591 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JF568_RS02130 (JF568_02130) 422558..423994 + 1437 WP_097113668.1 NAD-dependent succinate-semialdehyde dehydrogenase -
JF568_RS02135 (JF568_02135) 424168..424812 + 645 WP_097113557.1 5-oxoprolinase subunit PxpB -
JF568_RS02140 (JF568_02140) 425030..425959 + 930 WP_097113558.1 biotin-dependent carboxyltransferase family protein -
JF568_RS02145 (JF568_02145) 425972..426697 + 726 WP_097113559.1 hypothetical protein -
JF568_RS02150 (JF568_02150) 426717..427256 + 540 WP_097113560.1 hypothetical protein -
JF568_RS02155 (JF568_02155) 427337..427591 + 255 WP_097113561.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
JF568_RS02160 (JF568_02160) 427588..427848 + 261 WP_097113562.1 Txe/YoeB family addiction module toxin Toxin
JF568_RS02165 (JF568_02165) 428021..428758 + 738 WP_097113563.1 5-oxoprolinase subunit PxpA -
JF568_RS02170 (JF568_02170) 428797..429276 + 480 WP_097113564.1 hypothetical protein -
JF568_RS02175 (JF568_02175) 429405..430592 + 1188 WP_097113565.1 divalent metal cation transporter -
JF568_RS02180 (JF568_02180) 430695..431984 - 1290 WP_097113566.1 FAD-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10398.90 Da        Isoelectric Point: 6.7172

>T217805 WP_097113562.1 NZ_CP083931:427588-427848 [Alysiella filiformis DSM 16848]
MKLIFAETAWQDYVYWQTADRKILKRINLLIQDIQREPFDGIGKPEPLRFHLSGFWSRRIDEEHRLIYAIENESVLIASC
RYHYGE

Download         Length: 261 bp

>T217805 NZ_CP114853:c4931655-4930738 [Klebsiella pneumoniae]
ATGGATATACAGGCGCCTTATTATCGGCAGGTTGCTCTGCTAATGCAGGTTTTACCCTATGTTGCTGTCGAACGGGAATT
TGCGCTGAAAGGTGGCACTGCAATCAATCTCTTTATCCGCGATTTCCCTCGATTATCGGTGGATATCGACCTCGCCTGGG
TGCCCCTGGAAAGCAGAGCCATCGCTTTACCTCATATACGGGATGCGCTTGCACGTATTGCCGCCAATCTGCAACAACAG
GCAGGTATGAGCGCTGTATTACAAGCTAATCGTTCAGATGAGATGCGTGTCATTGTTACTACCGATAGCGCGCAAATAAA
GATAGAGGTTTCACCGGTCGCCCGGGGAACATTATATCCACCACAGGAGCGAGAAGTGGTGGGGGCGGTAGAGGACGTTT
TTGGCTATGCCAGCCTTCCAGTGGTTTCGTTGCCTGACCTCTACGGTGGAAAATTATGCGCGGCGCTGGATCGCCAGCAT
CCCAGAGATTTTTATGACGTGAAATTACTTCTTGATGCGCAGGAGCTTGACCGTCCCATTTTCAATGGGTTTATCGTGTA
TTTACTGAGCCATAATCGGCCTCTGGCTGAAGTGCTGAATCCTCGCTGGAAAGATATTGCTGAACCTTTTTACCGTGAAT
TCAGCGGGATGACATTTGAGACGATAGCCCTGGAGGAACTGACAGCAGTCCCCAACAGGATGATTGCTGCGTTAAAATCC
TGTTTCACACAACAGGATGTCGATTTTTTACTGTCATTTAAACGAGGCGAACCAGACTGGCGTTTAGCGCCGGAAATGCG
TATTCAGGATTTGCCTGCCGTGCAGTGGAAATTGCGCAATATTCATCAGATGCCAGCGATAAAACGCGCTGAGTCATTAG
ATAAACTGGAAAAGGTGCTGGCCGAGTGGCGCAGTTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9684.94 Da        Isoelectric Point: 6.7158

>AT217805 WP_097113561.1 NZ_CP083931:427337-427591 [Alysiella filiformis DSM 16848]
MHTLSYSEARQNLAKTMQEVVQNHEPVLITRTKNNEDCVLMSLAHYRSLEETAYLLRSPVNAQRLNQAIQQLKNGNGMER
ELSE

Download         Length: 255 bp

>AT217805 NZ_CP114853:c4932419-4931661 [Klebsiella pneumoniae]
ATGGCAACAAAATTAAACTGGCTGCTGCAAAACAGCGCTCCCGGAGATGTGATCCTTCAGTCCTGGTTAAGCCAGCATGC
CATCTCTCCCTCTCTGGCCTTTAAATACGCGCAAAGTGGCTGGTTAAAAAAAAGAGGCAACGGCGTATATGCGCGTGCGG
GACGTGAGCCGGAGTGGAACGATGCATTAGCATGTTTGCAAAATCAGCTTGCCGCTCCGGTGTATGTTGCGGGGCTCAGT
AGCTTAGTCTGGCAGGGCCGTTCACACTATCTACAGCTAAAACAAAACCAGTGCTGGCTTAGTGTGGAAAATAAAGCGCT
GCTGCCGAAATGGTTCAGGGAATTCCCGGGTGTGGAGTGGATAGTCATATCGGGGAAAAAACTGCCGGTGCTGGATGATA
GATACCGTGTAACGCTTGATATAAAAGGGAAAAAACTCATCGGCAGTGCGCCAGAACTGGCTGCTTACGAGTTGCTGAGC
GCGGTGCCGGGGACCCTCTCATTTAACCACGCTGCAGAGCTTTTCCAGGGGCTGGTTAATCTTAATCCTCGTAAAGTAGA
GTATCTTCTTTCCGTCAGCCAGTCCGTGCAGGCCAAGCGTTTGTATCTCTTCTTCGCCAGTTTTTACGAGCATGGCTGGC
TCAAACGAATCGATAGCCAAAAAATCGATCTGGGAGCGGGCAAGCGGCAAATCGTGGAAAATGGAAAGTTCAATGCTCAA
TACCAAATCACAGTGCCTGAACGCTTTCAAAAGGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References