Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | rlegTA/AbiEii-AbiEi |
| Location | 2830832..2832354 | Replicon | chromosome |
| Accession | NZ_CP083911 | ||
| Organism | Tepidimonas taiwanensis strain LMG 22826 | ||
Toxin (Protein)
| Gene name | rlegT | Uniprot ID | - |
| Locus tag | LCC91_RS13365 | Protein ID | WP_185974921.1 |
| Coordinates | 2831428..2832354 (+) | Length | 309 a.a. |
Antitoxin (Protein)
| Gene name | rlegA | Uniprot ID | A0A554X1L4 |
| Locus tag | LCC91_RS13360 | Protein ID | WP_024892246.1 |
| Coordinates | 2830832..2831431 (+) | Length | 200 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LCC91_RS13340 (LCC91_13340) | 2826584..2827276 | + | 693 | WP_185974920.1 | DUF4390 domain-containing protein | - |
| LCC91_RS13345 (LCC91_13345) | 2827273..2829579 | + | 2307 | WP_143898346.1 | ATP-binding protein | - |
| LCC91_RS13350 (LCC91_13350) | 2829595..2830365 | + | 771 | WP_143898348.1 | response regulator | - |
| LCC91_RS13360 (LCC91_13360) | 2830832..2831431 | + | 600 | WP_024892246.1 | AbiEi antitoxin N-terminal domain-containing protein | Antitoxin |
| LCC91_RS13365 (LCC91_13365) | 2831428..2832354 | + | 927 | WP_185974921.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
| LCC91_RS13370 (LCC91_13370) | 2832351..2832839 | + | 489 | WP_024892248.1 | hypothetical protein | - |
| LCC91_RS13375 (LCC91_13375) | 2832836..2833423 | + | 588 | WP_143898350.1 | NERD domain-containing protein | - |
| LCC91_RS13380 (LCC91_13380) | 2833455..2833886 | - | 432 | WP_143898352.1 | hypothetical protein | - |
| LCC91_RS13385 (LCC91_13385) | 2833883..2835241 | - | 1359 | WP_143898354.1 | recombinase family protein | - |
| LCC91_RS13390 (LCC91_13390) | 2835238..2835735 | - | 498 | WP_143898357.1 | DUF2924 domain-containing protein | - |
| LCC91_RS13395 (LCC91_13395) | 2835732..2835950 | - | 219 | WP_142805360.1 | hypothetical protein | - |
| LCC91_RS13400 (LCC91_13400) | 2836163..2837215 | + | 1053 | WP_143898359.1 | XRE family transcriptional regulator | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 2830832..2856986 | 26154 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 309 a.a. Molecular weight: 34681.53 Da Isoelectric Point: 5.6877
>T217791 WP_185974921.1 NZ_CP083911:2831428-2832354 [Tepidimonas taiwanensis]
MNQRNMAASVRARLLNRARETRQDFNLILTRYALERLLYRLSISPHADQFLLKGALLFDLWFDIPHRPTRDADLLGFGSA
EIPHVEAAFRDICTVELDDGIRFQPDSVHAEEIRKEANYSGVRVTLIGLLDGARCHVQVDVGFGDAVTPGPEAVDYPVML
PDMPAPKLRAYPRYTVVAEKLEALVSLGIANSRMKDYFDLWILSRYTDFDGALLCKAIHATFERRRTPLPDGVPFGLSDE
FAQDRQKQTQWQAFLRKNALDELQLSEVVAGLRAFLSFPLDALQQGAAFPQTWLAGNGWMSSGEESGR
MNQRNMAASVRARLLNRARETRQDFNLILTRYALERLLYRLSISPHADQFLLKGALLFDLWFDIPHRPTRDADLLGFGSA
EIPHVEAAFRDICTVELDDGIRFQPDSVHAEEIRKEANYSGVRVTLIGLLDGARCHVQVDVGFGDAVTPGPEAVDYPVML
PDMPAPKLRAYPRYTVVAEKLEALVSLGIANSRMKDYFDLWILSRYTDFDGALLCKAIHATFERRRTPLPDGVPFGLSDE
FAQDRQKQTQWQAFLRKNALDELQLSEVVAGLRAFLSFPLDALQQGAAFPQTWLAGNGWMSSGEESGR
Download Length: 927 bp
>T217791 NZ_CP114801:c4742870-4742496 [Citrobacter sp. 21OH12SH02A-Citro]
ATGGTCACAGGATCTGCGCTTTTTGATACCAACATCCTGATCGACCTGTTTAGCGGGCGAAGTGAAGCAAAACTAGCGAT
AGAAACATGGCCGCCGCAGAACGCAATCAGCCTCATTACATGGATGGAGTTGATGGTGGGAGCAAAAAAATATCATCAGG
AATCTCGCACACGCGTTGCGCTAGGCGCTTTTAATGTGATCGGTGTTTCACAGGATATTGCTGAACGAAGCGTGAGTATC
AGGCAGGAATATGGGATGAAATTGCCGGATGCCATCATTTTGGCCACTGCGCAGATTCATCGTCTTACACTGGTTACGCG
TAATACCAGGGATTTTGCAGGCATATCCGGCGTGGTCACACCGTATACGTTATAA
ATGGTCACAGGATCTGCGCTTTTTGATACCAACATCCTGATCGACCTGTTTAGCGGGCGAAGTGAAGCAAAACTAGCGAT
AGAAACATGGCCGCCGCAGAACGCAATCAGCCTCATTACATGGATGGAGTTGATGGTGGGAGCAAAAAAATATCATCAGG
AATCTCGCACACGCGTTGCGCTAGGCGCTTTTAATGTGATCGGTGTTTCACAGGATATTGCTGAACGAAGCGTGAGTATC
AGGCAGGAATATGGGATGAAATTGCCGGATGCCATCATTTTGGCCACTGCGCAGATTCATCGTCTTACACTGGTTACGCG
TAATACCAGGGATTTTGCAGGCATATCCGGCGTGGTCACACCGTATACGTTATAA
Antitoxin
Download Length: 200 a.a. Molecular weight: 22311.98 Da Isoelectric Point: 10.2174
>AT217791 WP_024892246.1 NZ_CP083911:2830832-2831431 [Tepidimonas taiwanensis]
MDSSHQSILDLAAQRGLIRPRDLNERGLPTIALTRLVRQGLLQRVGRGLYAIPDRAVSEHGALSEVARKHPQAIVCLLSA
LRLHELTTQSPFEVWLAIPNKARAPKMDYPPLRIVRFSGAALTEGVEEHLIDGVPVRVTNVARTVADCFKFRNKIGLDVA
LEALQESWRAKRVSMDELWRFAALCRVANVMRPYMESLS
MDSSHQSILDLAAQRGLIRPRDLNERGLPTIALTRLVRQGLLQRVGRGLYAIPDRAVSEHGALSEVARKHPQAIVCLLSA
LRLHELTTQSPFEVWLAIPNKARAPKMDYPPLRIVRFSGAALTEGVEEHLIDGVPVRVTNVARTVADCFKFRNKIGLDVA
LEALQESWRAKRVSMDELWRFAALCRVANVMRPYMESLS
Download Length: 600 bp
>AT217791 NZ_CP114801:c4743112-4742870 [Citrobacter sp. 21OH12SH02A-Citro]
ATGATGGCTGGGATGGATATGGGCAGAATTTTACTCGATTTATCAGACGAAGTGATCAAACGTCTTGATGATCTCAAGGT
GCAGCGTAATCTGCCGCGGGCTGAGCTTTTGCGGGAGGCTGTTGAACAGTATCTTGAGAGGCAGGATCAAGCTGAAACGA
CAATTTCACGTGCTCTTGGGCTATGGCAAGGTTGTGAGGAAGATGGCGTTGATTATCAGCGTAAACTCCGCGAGGAATGG
TAA
ATGATGGCTGGGATGGATATGGGCAGAATTTTACTCGATTTATCAGACGAAGTGATCAAACGTCTTGATGATCTCAAGGT
GCAGCGTAATCTGCCGCGGGCTGAGCTTTTGCGGGAGGCTGTTGAACAGTATCTTGAGAGGCAGGATCAAGCTGAAACGA
CAATTTCACGTGCTCTTGGGCTATGGCAAGGTTGTGAGGAAGATGGCGTTGATTATCAGCGTAAACTCCGCGAGGAATGG
TAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|