Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 1865333..1865814 Replicon chromosome
Accession NZ_CP083911
Organism Tepidimonas taiwanensis strain LMG 22826

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LCC91_RS08795 Protein ID WP_224440895.1
Coordinates 1865333..1865563 (-) Length 77 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LCC91_RS08800 Protein ID WP_043702202.1
Coordinates 1865563..1865814 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LCC91_RS08770 (LCC91_08770) 1860693..1860977 + 285 WP_043698441.1 nucleotidyltransferase family protein -
LCC91_RS08775 (LCC91_08775) 1861000..1861353 + 354 WP_043698438.1 DUF86 domain-containing protein -
LCC91_RS08780 (LCC91_08780) 1861505..1861822 + 318 WP_221934162.1 nucleotidyltransferase family protein -
LCC91_RS08785 (LCC91_08785) 1861934..1863715 + 1782 WP_043698435.1 sigma-54 dependent transcriptional regulator -
LCC91_RS08790 (LCC91_08790) 1864023..1865305 + 1283 WP_224440894.1 IS3 family transposase -
LCC91_RS08795 (LCC91_08795) 1865333..1865563 - 231 WP_224440895.1 hypothetical protein Toxin
LCC91_RS08800 (LCC91_08800) 1865563..1865814 - 252 WP_043702202.1 hypothetical protein Antitoxin
LCC91_RS08805 (LCC91_08805) 1866031..1866483 + 453 WP_052231658.1 HI0074 family nucleotidyltransferase substrate-binding subunit -
LCC91_RS08810 (LCC91_08810) 1866480..1866785 + 306 WP_043702191.1 nucleotidyltransferase domain-containing protein -
LCC91_RS08815 (LCC91_08815) 1866990..1867103 + 114 Protein_1720 prepilin-type N-terminal cleavage/methylation domain-containing protein -
LCC91_RS08820 (LCC91_08820) 1867371..1867499 + 129 Protein_1721 prepilin-type N-terminal cleavage/methylation domain-containing protein -
LCC91_RS08825 (LCC91_08825) 1867847..1869742 + 1896 WP_143898532.1 hypothetical protein -
LCC91_RS08830 (LCC91_08830) 1869739..1870596 + 858 WP_043702178.1 glycosyltransferase family 2 protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1864412..1880287 15875


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 77 a.a.        Molecular weight: 8151.40 Da        Isoelectric Point: 7.4363

>T217786 WP_224440895.1 NZ_CP083911:c1865563-1865333 [Tepidimonas taiwanensis]
MRALLDVNVLIALLDAGHAHHARATEWLAAELHHGWASCPLTQNGCLRIMSQPGYPSPLPVRAVAERLAQAAAHPS

Download         Length: 231 bp

>T217786 NZ_CP114801:c2825058-2824955 [Citrobacter sp. 21OH12SH02A-Citro]
GGCAGGGTAACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 8527.65 Da        Isoelectric Point: 6.2469

>AT217786 WP_043702202.1 NZ_CP083911:c1865814-1865563 [Tepidimonas taiwanensis]
VRTTIDLEPDVLEAAKELARQQNTAVGKVISRLVRQALTGTATAAAPQGDGTAASVAGFVPFPARGTVVTNALIDRLRDA
EGA

Download         Length: 252 bp

>AT217786 NZ_CP114801:2824950-2825093 [Citrobacter sp. 21OH12SH02A-Citro]
CACATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTT
GGCATTAATGCAGGCTAAGTTACCCTGCCATTTAAGAATAGATGACAGCGCCAGGTTTTCCAGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References