Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbE-relB/ParE-YafN
Location 1471590..1472115 Replicon chromosome
Accession NZ_CP083911
Organism Tepidimonas taiwanensis strain LMG 22826

Toxin (Protein)


Gene name stbE Uniprot ID A0A554WZJ2
Locus tag LCC91_RS06770 Protein ID WP_043699056.1
Coordinates 1471590..1471871 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A554WZN0
Locus tag LCC91_RS06775 Protein ID WP_043699054.1
Coordinates 1471861..1472115 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LCC91_RS06755 (LCC91_06755) 1466697..1467272 - 576 WP_043699060.1 TetR/AcrR family transcriptional regulator -
LCC91_RS06760 (LCC91_06760) 1467435..1468508 + 1074 WP_143898492.1 efflux RND transporter periplasmic adaptor subunit -
LCC91_RS06765 (LCC91_06765) 1468505..1471579 + 3075 WP_043699058.1 efflux RND transporter permease subunit -
LCC91_RS06770 (LCC91_06770) 1471590..1471871 - 282 WP_043699056.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LCC91_RS06775 (LCC91_06775) 1471861..1472115 - 255 WP_043699054.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LCC91_RS06780 (LCC91_06780) 1472220..1473437 - 1218 WP_043699053.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
LCC91_RS06785 (LCC91_06785) 1473555..1475213 + 1659 WP_043699051.1 CTP synthase -
LCC91_RS06790 (LCC91_06790) 1475210..1476067 + 858 WP_043699049.1 3-deoxy-8-phosphooctulonate synthase -
LCC91_RS06795 (LCC91_06795) 1476118..1476408 + 291 WP_043699046.1 DUF1330 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10814.57 Da        Isoelectric Point: 11.0069

>T217782 WP_043699056.1 NZ_CP083911:c1471871-1471590 [Tepidimonas taiwanensis]
MRYELAFHPAAWREWQALDGSVRTILKRKLAERLEQPRVPAAQLAGHPDRYKIKLRSAGYRLVYEVRDAEVVVIVIAVGK
RERSAVYRAADRR

Download         Length: 282 bp

>T217782 NZ_CP114798:c29592-29260 [Providencia sp. 21OH12SH02B-Prov]
ATGGTATCTCGATACGTTCCTGATTCTGGCGATTTGATTTGGATTGACTTTGATCCAGTTGAAGGACATGAGCAGGGCGG
TCATCGTCCAGCAGTTGTCCTCAGCCCATTTGCATACAATAATAAAGTAGGGCTCTTATTATGCGTACCATGTACAACTA
AGGGCAAAGGCTATCCATTTGAATGCGAACTCTCGAACGAAAGAGACAGCTACGCATTAGCGGATCAAGTTACATGTGTT
GACTGGAGAGCTCGTAAGGTTACTAAAAAGGGCAAAGTGGAGGCATCAGAACTGGCAGAGATAAAAGCTAAAGCAAAGGC
GTTAATAGGTTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9025.39 Da        Isoelectric Point: 4.3455

>AT217782 WP_043699054.1 NZ_CP083911:c1472115-1471861 [Tepidimonas taiwanensis]
MPHVLLAPVAASVTELKRDPMGTVQAGEGGPVAILNRNEPAFYCVPATAFEALMERLEDLELNALADARLRDGQPLQRVS
LDAL

Download         Length: 255 bp

>AT217782 NZ_CP114798:c29837-29592 [Providencia sp. 21OH12SH02B-Prov]
ATGGCTCAGGTCACAGTAAAAAAATGGGGCAATAGCCCGTCTGTACGGCTTCCTGTTGCAATCATGCAAAAAGCGGCACT
TAGCGTTGATGATACGGTTGAAATAGCGGTAGAAGAAGGTCGTATCATCATTACGCCAGTTAAAGCAGTAGAATACTCAT
TAGAAAATTTGTTAGCCGGTATCACGCCGGAGAATATTCATGAGAAAGTAGACTTCGGAGCTCGAACAGGTAAGGAATTA
ATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A554WZJ2

Antitoxin

Source ID Structure
AlphaFold DB A0A554WZN0

References