Detailed information of TA system TA217780

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 169990..170581
• Replicon: chromosome
• Accession: NZ_CP083911
• Organism: Tepidimonas taiwanensis strain LMG 22826

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: LCC91_RS00825
• Protein ID: WP_043700452.1
• Coordinates: 170228..170581 (+)
• Length: 118 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: LCC91_RS00820
• Protein ID: WP_143897412.1
• Coordinates: 169990..170241 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LCC91_RS00805 (LCC91_00805)	165564..167453	+	1890	WP_052231522.1	bifunctional isocitrate dehydrogenase kinase/phosphatase	-
LCC91_RS00810 (LCC91_00810)	167450..168637	+	1188	WP_043700444.1	acetyl-CoA C-acyltransferase	-
LCC91_RS00815 (LCC91_00815)	168718..169845	+	1128	WP_043700447.1	acyl-CoA dehydrogenase family protein	-
LCC91_RS00820 (LCC91_00820)	169990..170241	+	252	WP_143897412.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
LCC91_RS00825 (LCC91_00825)	170228..170581	+	354	WP_043700452.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
LCC91_RS00830 (LCC91_00830)	170639..172030	+	1392	WP_043700454.1	Trk system potassium transporter TrkA	-
LCC91_RS00835 (LCC91_00835)	172040..173512	+	1473	WP_043700456.1	potassium transporter TrkG	-
LCC91_RS00840 (LCC91_00840)	173522..174991	+	1470	WP_143897411.1	potassium transporter TrkG	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integrative and Conjugative Element	-	pilT / cheY	20246..262494	242248

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (18-97)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (10-77)

Sequences

Toxin

Protein

• Length: 118 a.a.
• Molecular weight: 13223.51 Da
• Isoelectric Point: 10.9276

>T217780 WP_043700452.1 NZ_CP083911:170228-170581 [Tepidimonas taiwanensis]
MRTSDPPGAQPPQPYRLHFMPEALEEWHRLDGSVKASLKKLLKKRLVQPHVPGGALTGPLAGCYKIKLRKQGVRLVYAVE
DDRPIVLVLAIDRRERDQVYRSALVRVSAPPDRPKGR

Nucleotide

• Length: 354 bp

>T217780 NZ_CP083911:170228-170581 [Tepidimonas taiwanensis]
TTGAGGACCTCTGACCCCCCTGGCGCGCAGCCACCGCAGCCGTACCGCTTGCATTTCATGCCGGAGGCACTGGAGGAGTG
GCACCGTCTGGATGGATCGGTCAAGGCCAGCCTGAAAAAGCTGCTCAAAAAGCGTCTCGTACAGCCTCATGTACCCGGTG
GTGCCCTGACGGGTCCGTTGGCGGGCTGCTACAAAATCAAGTTGCGCAAGCAAGGGGTGCGGTTGGTGTACGCGGTCGAG
GACGACCGCCCCATCGTCCTGGTGCTGGCGATCGACAGACGGGAGCGCGACCAGGTTTACCGATCGGCCCTCGTACGCGT
CTCTGCCCCGCCGGATCGGCCCAAAGGGCGATGA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9461.91 Da
• Isoelectric Point: 6.7261

>AT217780 WP_143897412.1 NZ_CP083911:169990-170241 [Tepidimonas taiwanensis]
METILADVAVSMSEFKKNPAAVLRHAHRRPVAVLSHNRPAFYMIEPRLFEDIMEALADQDLYRRAASRLAEKGRAVEVNL
EDL

Nucleotide

• Length: 252 bp

>AT217780 NZ_CP083911:169990-170241 [Tepidimonas taiwanensis]
ATGGAAACCATACTGGCCGATGTCGCCGTCAGCATGTCGGAATTCAAGAAGAACCCTGCCGCGGTGCTGCGGCACGCACA
CCGTCGTCCGGTGGCGGTCTTGAGTCACAACCGCCCCGCGTTCTACATGATCGAACCCCGACTGTTCGAGGACATCATGG
AAGCGTTGGCGGATCAGGATCTGTACCGTCGGGCCGCCAGCCGTCTGGCCGAGAAAGGGCGGGCCGTCGAGGTGAACCTT
GAGGACCTCTGA