Detailed information of TA system TA021777

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YafQ-DinJ
• Location: 3279087..3279617
• Replicon: chromosome
• Accession: NC_008576
• Organism: Magnetococcus marinus MC-1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: MMC1_RS13170
• Protein ID: WP_143711429.1
• Coordinates: 3279372..3279617 (+)
• Length: 82 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: MMC1_RS13165
• Protein ID: WP_041641240.1
• Coordinates: 3279087..3279344 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MMC1_RS13125	3274120..3274491	-	372	WP_011714184.1	hypothetical protein	-
MMC1_RS13130	3274494..3275411	-	918	WP_011712996.1	hypothetical protein	-
MMC1_RS13135	3275423..3275680	-	258	WP_011712995.1	hypothetical protein	-
MMC1_RS13140	3275683..3276000	-	318	WP_011714185.1	hypothetical protein	-
MMC1_RS13145	3276003..3277016	-	1014	WP_011712993.1	major capsid protein	-
MMC1_RS20290	3277019..3277684	-	666	WP_011712992.1	head decoration protein	-
MMC1_RS13160	3277699..3278955	-	1257	WP_011714186.1	S49 family peptidase	-
MMC1_RS13165	3279087..3279344	+	258	WP_041641240.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
MMC1_RS13170	3279372..3279617	+	246	WP_143711429.1	type II toxin-antitoxin system YafQ family toxin	Toxin
MMC1_RS13175	3279623..3281107	-	1485	WP_011714188.1	phage portal protein	-
MMC1_RS13180	3281107..3281322	-	216	WP_041640929.1	hypothetical protein	-
MMC1_RS13185	3281358..3281639	+	282	WP_011714189.1	hypothetical protein	-
MMC1_RS13190	3281640..3283496	-	1857	WP_011714190.1	phage terminase large subunit family protein	-
MMC1_RS13195	3283591..3283788	+	198	WP_011714191.1	hypothetical protein	-
MMC1_RS13200	3283815..3284198	+	384	WP_011713684.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	3259207..3325385	66178

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (21-81)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-84)

Sequences

Toxin

Protein

• Length: 82 a.a.
• Molecular weight: 9552.02 Da
• Isoelectric Point: 6.2084

>T21777 WP_143711429.1 NC_008576:3279372-3279617 [Magnetococcus marinus MC-1]
MRKISRKLKNAARIWVSLNPSLIRWLLENPLPADFVPHRLTGNWDGCWECHIESDWLLIWVDEQEETIILTRLGTHSDLF
G

Nucleotide

• Length: 246 bp

>T21777 NC_008576:3279372-3279617 [Magnetococcus marinus MC-1]
TTGAGAAAGATCTCAAGAAAGCTAAAAAACGCGGCAAGGATCTGGGTAAGCTTAAATCCGTCATTGATACGTTGGCTTCT
GGAGAACCCCTTGCCAGCAGATTTCGTCCCCCACCGTCTGACGGGCAATTGGGACGGATGCTGGGAGTGTCATATTGAAT
CTGATTGGCTACTGATCTGGGTGGATGAGCAAGAAGAAACCATTATCCTGACTCGACTTGGAACACACTCTGACCTCTTT
GGCTGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9607.01 Da
• Isoelectric Point: 5.1271

>AT21777 WP_041641240.1 NC_008576:3279087-3279344 [Magnetococcus marinus MC-1]
MAKTEMIRARVELETKQAAEDIFRTLGISASEAITMFYRQVALHHGIPFEVKIPNTETIEALNQARKGEALTTWNSVDEL
MKSVE

Nucleotide

• Length: 258 bp

>AT21777 NC_008576:3279087-3279344 [Magnetococcus marinus MC-1]
ATGGCTAAAACAGAGATGATTCGGGCCCGTGTAGAACTGGAAACAAAGCAGGCCGCTGAAGACATTTTCAGGACACTTGG
TATTTCAGCTTCCGAGGCGATCACGATGTTCTATCGCCAAGTAGCGCTGCACCATGGCATACCCTTCGAGGTAAAAATTC
CCAATACAGAAACGATTGAGGCGCTAAATCAGGCCCGTAAAGGTGAAGCCCTCACCACCTGGAACTCAGTAGATGAGCTA
ATGAAGAGCGTTGAATGA