Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2062593..2062864 Replicon chromosome
Accession NZ_CP083888
Organism Escherichia coli strain NDM1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2062723..2062826 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2062593..2062864 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LCE25_RS09930 2059148..2059810 - 663 WP_000944256.1 exodeoxyribonuclease X -
LCE25_RS09935 2059834..2060490 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
LCE25_RS09940 2060592..2060822 - 231 WP_000916763.1 DNA polymerase III subunit theta -
LCE25_RS09945 2060961..2061335 + 375 WP_000204699.1 CopC domain-containing protein YobA -
LCE25_RS09950 2061339..2062211 + 873 WP_000879334.1 copper homeostasis membrane protein CopD -
LCE25_RS09955 2062224..2062565 + 342 WP_000976492.1 YebY family protein -
- 2062593..2062864 - 272 - - Antitoxin
- 2062723..2062826 + 104 - - Toxin
LCE25_RS09960 2062961..2063617 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
LCE25_RS09965 2063618..2063809 - 192 WP_001296140.1 YebW family protein -
LCE25_RS09970 2063914..2064150 - 237 WP_001295499.1 YebV family protein -
LCE25_RS09975 2064268..2065707 - 1440 WP_000057024.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T217750 NZ_CP083888:2062723-2062826 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGGCCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT217750 NZ_CP083888:c2062864-2062593 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGCCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References