Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2031704..2031975 Replicon chromosome
Accession NZ_CP083886
Organism Escherichia coli strain NDM2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2031834..2031937 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2031704..2031975 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LCE23_RS10750 2028259..2028921 - 663 WP_000944256.1 exodeoxyribonuclease X -
LCE23_RS10755 2028945..2029601 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
LCE23_RS10760 2029703..2029933 - 231 WP_000916763.1 DNA polymerase III subunit theta -
LCE23_RS10765 2030072..2030446 + 375 WP_000168747.1 CopC domain-containing protein YobA -
LCE23_RS10770 2030450..2031322 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
LCE23_RS10775 2031335..2031676 + 342 WP_000976476.1 YebY family protein -
- 2031704..2031975 - 272 - - Antitoxin
- 2031834..2031937 + 104 - - Toxin
LCE23_RS10780 2032072..2032728 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
LCE23_RS10785 2032729..2032920 - 192 WP_000457842.1 YebW family protein -
LCE23_RS10790 2033025..2033261 - 237 WP_001295499.1 YebV family protein -
LCE23_RS10795 2033379..2034818 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T217728 NZ_CP083886:2031834-2031937 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT217728 NZ_CP083886:c2031975-2031704 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References