Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2007478..2007749 Replicon chromosome
Accession NZ_CP083880
Organism Escherichia coli strain NDM3

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2007608..2007711 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2007478..2007749 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LCE26_RS09655 2004033..2004695 - 663 WP_000944256.1 exodeoxyribonuclease X -
LCE26_RS09660 2004719..2005375 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
LCE26_RS09665 2005477..2005707 - 231 WP_000916763.1 DNA polymerase III subunit theta -
LCE26_RS09670 2005846..2006220 + 375 WP_000168747.1 CopC domain-containing protein YobA -
LCE26_RS09675 2006224..2007096 + 873 WP_042346164.1 copper homeostasis membrane protein CopD -
LCE26_RS09680 2007109..2007450 + 342 WP_000976476.1 YebY family protein -
- 2007478..2007749 - 272 - - Antitoxin
- 2007608..2007711 + 104 - - Toxin
LCE26_RS09685 2007846..2008502 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
LCE26_RS09690 2008503..2008694 - 192 WP_000457842.1 YebW family protein -
LCE26_RS09695 2008799..2009035 - 237 WP_001295499.1 YebV family protein -
LCE26_RS09700 2009153..2010592 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T217689 NZ_CP083880:2007608-2007711 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT217689 NZ_CP083880:c2007749-2007478 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References