Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2007462..2007733 Replicon chromosome
Accession NZ_CP083877
Organism Escherichia coli strain NDM4

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2007592..2007695 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2007462..2007733 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LCE22_RS09655 2004017..2004679 - 663 WP_000944256.1 exodeoxyribonuclease X -
LCE22_RS09660 2004703..2005359 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
LCE22_RS09665 2005461..2005691 - 231 WP_000916763.1 DNA polymerase III subunit theta -
LCE22_RS09670 2005830..2006204 + 375 WP_000168747.1 CopC domain-containing protein YobA -
LCE22_RS09675 2006208..2007080 + 873 WP_042346164.1 copper homeostasis membrane protein CopD -
LCE22_RS09680 2007093..2007434 + 342 WP_000976476.1 YebY family protein -
- 2007462..2007733 - 272 - - Antitoxin
- 2007592..2007695 + 104 - - Toxin
LCE22_RS09685 2007830..2008486 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
LCE22_RS09690 2008487..2008678 - 192 WP_000457842.1 YebW family protein -
LCE22_RS09695 2008783..2009019 - 237 WP_001295499.1 YebV family protein -
LCE22_RS09700 2009137..2010576 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T217662 NZ_CP083877:2007592-2007695 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT217662 NZ_CP083877:c2007733-2007462 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References