Detailed information of TA system TA217422

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): ypjF-yeeU/CbtA-CbeA
• Location: 3453332..3454065
• Replicon: chromosome
• Accession: NZ_CP083815
• Organism: Enterobacter asburiae strain 161373-yvys

Toxin (Protein)

• Gene name: ypjF
• Uniprot ID: -
• Locus tag: LCD39_RS16845
• Protein ID: WP_078309458.1
• Coordinates: 3453736..3454065 (+)
• Length: 110 a.a.

Antitoxin (Protein)

• Gene name: yeeU
• Uniprot ID: -
• Locus tag: LCD39_RS16840
• Protein ID: WP_078309456.1
• Coordinates: 3453332..3453697 (+)
• Length: 122 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	luxS	3432427..3508817	76390

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• CbtA toxin of type IV toxin-antitoxin system (2-107)

Antitoxin

• Antitoxin CbeA (17-117)

Sequences

Toxin

Protein

• Length: 110 a.a.
• Molecular weight: 12303.17 Da
• Isoelectric Point: 8.5043

>T217422 WP_078309458.1 NZ_CP083815:3453736-3454065 [Enterobacter asburiae]
MQIISSAPTRAAPLSLSPVEIWQRLLTHLLSQHYGLTLNDTPFSYETTIREHIDAGVSLSDAVNFLVEKYGLVRIDRKGF
SWQEQTPYISVVDILMARRSTGLLKTTVK

Nucleotide

• Length: 330 bp

>T217422 NZ_CP114281:755104-755388 [Gallibacterium anatis]
ATGGCAGAACAATTAAAAGACTTTGATATGTCAGAACATTTACGCACAGAAGAAGAAATACAGCTCTATCTTAATGAGAT
TTTAAGTGAGGGCGATATTGATTTATTGCTTTCTGCATTAGGTGATATAGCGAAAGCGAGAAATATGAGTCAAATTGCTC
GAGAAGTGGGGGTAACAAGAGAAGGGTTATATAAAGCTCTTTCTGGGCGAGGCAATCCAACATTTGCCACTGTGTTTAAG
GTAATGCAGGCGTTAAATTTGAATTTAGAAGTAAAACACGCTTAA

Antitoxin

Protein

• Length: 122 a.a.
• Molecular weight: 13427.12 Da
• Isoelectric Point: 5.4451

>AT217422 WP_078309456.1 NZ_CP083815:3453332-3453697 [Enterobacter asburiae]
MNNHSESGTRPENSAIQQWGLKRAITPCFGARLVQEGNRLHYLADRAGFSGAFTDDVAMHLDQAFPLMMKQLELMLTSGE
LNPSHPHCVTLYHNGLTCEADTLGSCGYVYIAIYPEQTEPQ

Nucleotide

• Length: 366 bp

>AT217422 NZ_CP114281:754806-755102 [Gallibacterium anatis]
ATGATTCAGATAAAATCAACAGAAGCCTTTGATAAATGGCTAGATAATCTTAAGGATTTGCGGGCAAGGGCTAAAATTCA
AGTGCGGATTAAACGATTACAGCTTGGCAATTTTGGTGATGTAAAGCCGATAGGTGAAGGGTTATCTGAATTAAGAATAA
CAGAAGGGAAAGGCTATCGCCTGTACTTGAAAAATCAAAATGGGGTGATTGTGATTTTGTTATGCGGTGGCGACAAATCC
ACACAGAAAGCGGATATTGAGAAAGCAAAATCGTTAGCAAAGATATTAGGAGTTTAA