Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | kacAT/DUF1778(antitoxin) |
| Location | 1626415..1627212 | Replicon | chromosome |
| Accession | NZ_CP083815 | ||
| Organism | Enterobacter asburiae strain 161373-yvys | ||
Toxin (Protein)
| Gene name | KacT | Uniprot ID | - |
| Locus tag | LCD39_RS07810 | Protein ID | WP_172421424.1 |
| Coordinates | 1626712..1627212 (+) | Length | 167 a.a. |
Antitoxin (Protein)
| Gene name | KacA | Uniprot ID | W7PG43 |
| Locus tag | LCD39_RS07805 | Protein ID | WP_008499829.1 |
| Coordinates | 1626415..1626684 (+) | Length | 90 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LCD39_RS07775 (LCD39_07780) | 1622042..1622485 | - | 444 | WP_032658095.1 | helix-turn-helix domain-containing protein | - |
| LCD39_RS07780 (LCD39_07785) | 1622638..1623879 | + | 1242 | WP_033145159.1 | bifunctional glucose-1-phosphatase/inositol phosphatase | - |
| LCD39_RS07785 (LCD39_07790) | 1623913..1624140 | - | 228 | WP_008499832.1 | YccJ family protein | - |
| LCD39_RS07790 (LCD39_07795) | 1624161..1624757 | - | 597 | WP_023311076.1 | NAD(P)H:quinone oxidoreductase | - |
| LCD39_RS07795 (LCD39_07800) | 1625148..1625318 | + | 171 | WP_023311077.1 | general stress protein | - |
| LCD39_RS07800 (LCD39_07805) | 1625436..1626353 | + | 918 | WP_033145161.1 | DMT family transporter | - |
| LCD39_RS07805 (LCD39_07810) | 1626415..1626684 | + | 270 | WP_008499829.1 | DUF1778 domain-containing protein | Antitoxin |
| LCD39_RS07810 (LCD39_07815) | 1626712..1627212 | + | 501 | WP_172421424.1 | GNAT family N-acetyltransferase | Toxin |
| LCD39_RS07815 (LCD39_07820) | 1627286..1628608 | - | 1323 | WP_023311081.1 | pyrimidine utilization transport protein G | - |
| LCD39_RS07820 (LCD39_07825) | 1628630..1629124 | - | 495 | WP_246948059.1 | pyrimidine utilization flavin reductase protein F | - |
| LCD39_RS07825 (LCD39_07830) | 1629134..1629724 | - | 591 | WP_246947510.1 | malonic semialdehyde reductase | - |
| LCD39_RS07830 (LCD39_07835) | 1629734..1630534 | - | 801 | WP_246947511.1 | pyrimidine utilization protein D | - |
| LCD39_RS07835 (LCD39_07840) | 1630542..1630928 | - | 387 | WP_010429508.1 | pyrimidine utilization protein C | - |
| LCD39_RS07840 (LCD39_07845) | 1630940..1631629 | - | 690 | WP_033145167.1 | pyrimidine utilization protein B | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 167 a.a. Molecular weight: 18969.67 Da Isoelectric Point: 7.9145
>T217412 WP_172421424.1 NZ_CP083815:1626712-1627212 [Enterobacter asburiae]
MLSEGTDYDFEDFDCGEPSLNAFLAEHLVRQHNGRILRAYLLKERDRPRVLGYYTLSGSCFERAMLPSKTQQRRIPYINV
PSVTLGRLAVDKTLQGNEWGTTLVAHAMRVVYLASQAVGVHGIFVDALNERAKRFYLKQGFIPLTAENSHSLFFPTKSIE
RLFEQE
MLSEGTDYDFEDFDCGEPSLNAFLAEHLVRQHNGRILRAYLLKERDRPRVLGYYTLSGSCFERAMLPSKTQQRRIPYINV
PSVTLGRLAVDKTLQGNEWGTTLVAHAMRVVYLASQAVGVHGIFVDALNERAKRFYLKQGFIPLTAENSHSLFFPTKSIE
RLFEQE
Download Length: 501 bp
>T217412 NZ_CP114280:c1830682-1830251 [Dickeya lacustris]
GTGGCCCAGTGGCAATGTGATCTGCGCGTATCCTGGCGCATGCAATTGTTTTCGCTGATGATGCACGGTTTTCTGGTGCT
GATGATCCTGCTGGCCCCCTGGCCAGATGGCTATGCACCACTATGGCTGGGGCTGCTGACGCTGGTGGTGTTTGGGTTTG
TGCGCAGCCAGCGTGTGATTAAACTGCGTCAGGGTGAGATAGCGCTGCATGATGAGAACCGCCTGCGTTGGCAACAGCGG
GACTGGCTGATGGTACGGCGGCCCTGGATGTTGCGCAGCGGTATCTTGCTGTCATTGCGGGCGGTGAATGGCAAAGAACA
GCAGCGGCTGTGGCTGGCATCTGACAGTATGGGAAGTGAAGAGTGGCGGCGATTATGCCAGCTATTGCGGCAGCAACCAT
TAGCGGGCATTCAGTCCTCCCGTCACCACTAA
GTGGCCCAGTGGCAATGTGATCTGCGCGTATCCTGGCGCATGCAATTGTTTTCGCTGATGATGCACGGTTTTCTGGTGCT
GATGATCCTGCTGGCCCCCTGGCCAGATGGCTATGCACCACTATGGCTGGGGCTGCTGACGCTGGTGGTGTTTGGGTTTG
TGCGCAGCCAGCGTGTGATTAAACTGCGTCAGGGTGAGATAGCGCTGCATGATGAGAACCGCCTGCGTTGGCAACAGCGG
GACTGGCTGATGGTACGGCGGCCCTGGATGTTGCGCAGCGGTATCTTGCTGTCATTGCGGGCGGTGAATGGCAAAGAACA
GCAGCGGCTGTGGCTGGCATCTGACAGTATGGGAAGTGAAGAGTGGCGGCGATTATGCCAGCTATTGCGGCAGCAACCAT
TAGCGGGCATTCAGTCCTCCCGTCACCACTAA
Antitoxin
Download Length: 90 a.a. Molecular weight: 10262.72 Da Isoelectric Point: 5.8836
>AT217412 WP_008499829.1 NZ_CP083815:1626415-1626684 [Enterobacter asburiae]
MPALKKQRIDLRLTDEDKTMIEEAAAMTNQTITQFMVNSASERAAEVIEQHRRLVLNEASWNAVMDAIDNPPEPNERLKR
AAKRLRNME
MPALKKQRIDLRLTDEDKTMIEEAAAMTNQTITQFMVNSASERAAEVIEQHRRLVLNEASWNAVMDAIDNPPEPNERLKR
AAKRLRNME
Download Length: 270 bp
>AT217412 NZ_CP114280:c1830929-1830663 [Dickeya lacustris]
ATGGATATTGATAATAAATCACGTATTCACTGGGCATGTCGGCGCGGAATGCGCGAATTGGATATCTCCATCATGCCGTT
TTTTGAGCATGAATATGACGGGTTAAGCGATGATGATAAGCGTCAGTTTATTCGTTTGCTGGAGTGCGATGATCCCGATC
TGTTTAACTGGTTGATGAATCATGGCGAGCCGCAGGATCCGGGCCTGAAACGTATGGTGTCCCTCATTCAGACGCGAAAT
AAAGATCGTGGCCCAGTGGCAATGTGA
ATGGATATTGATAATAAATCACGTATTCACTGGGCATGTCGGCGCGGAATGCGCGAATTGGATATCTCCATCATGCCGTT
TTTTGAGCATGAATATGACGGGTTAAGCGATGATGATAAGCGTCAGTTTATTCGTTTGCTGGAGTGCGATGATCCCGATC
TGTTTAACTGGTTGATGAATCATGGCGAGCCGCAGGATCCGGGCCTGAAACGTATGGTGTCCCTCATTCAGACGCGAAAT
AAAGATCGTGGCCCAGTGGCAATGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|