Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | PumAB/COG3657-dnstrm_HI1420 |
Location | 251186..251778 | Replicon | chromosome |
Accession | NZ_CP083815 | ||
Organism | Enterobacter asburiae strain 161373-yvys |
Toxin (Protein)
Gene name | PumA | Uniprot ID | - |
Locus tag | LCD39_RS01135 | Protein ID | WP_033144376.1 |
Coordinates | 251476..251778 (-) | Length | 101 a.a. |
Antitoxin (Protein)
Gene name | PumB | Uniprot ID | A0A808IFF3 |
Locus tag | LCD39_RS01130 | Protein ID | WP_033144375.1 |
Coordinates | 251186..251473 (-) | Length | 96 a.a. |
Genomic Context
Location: 249558..251189 (1632 bp)
Type: Others
Protein ID: WP_033144374.1
Type: Others
Protein ID: WP_033144374.1
Location: 251976..252848 (873 bp)
Type: Others
Protein ID: WP_023309993.1
Type: Others
Protein ID: WP_023309993.1
Location: 251186..251473 (288 bp)
Type: Antitoxin
Protein ID: WP_033144375.1
Type: Antitoxin
Protein ID: WP_033144375.1
Location: 251476..251778 (303 bp)
Type: Toxin
Protein ID: WP_033144376.1
Type: Toxin
Protein ID: WP_033144376.1
Location: 252849..253121 (273 bp)
Type: Others
Protein ID: WP_023309994.1
Type: Others
Protein ID: WP_023309994.1
Location: 253172..254116 (945 bp)
Type: Others
Protein ID: WP_048977786.1
Type: Others
Protein ID: WP_048977786.1
Location: 254210..255559 (1350 bp)
Type: Others
Protein ID: WP_246946881.1
Type: Others
Protein ID: WP_246946881.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LCD39_RS01125 (LCD39_01125) | 249558..251189 | + | 1632 | WP_033144374.1 | Na/Pi cotransporter family protein | - |
LCD39_RS01130 (LCD39_01130) | 251186..251473 | - | 288 | WP_033144375.1 | putative addiction module antidote protein | Antitoxin |
LCD39_RS01135 (LCD39_01135) | 251476..251778 | - | 303 | WP_033144376.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
LCD39_RS01140 (LCD39_01140) | 251976..252848 | + | 873 | WP_023309993.1 | 23S rRNA pseudouridine(2604) synthase RluF | - |
LCD39_RS01145 (LCD39_01145) | 252849..253121 | - | 273 | WP_023309994.1 | DUF3811 domain-containing protein | - |
LCD39_RS01150 (LCD39_01150) | 253172..254116 | - | 945 | WP_048977786.1 | ketopantoate/pantoate/pantothenate transporter PanS | - |
LCD39_RS01155 (LCD39_01155) | 254210..255559 | - | 1350 | WP_246946881.1 | lysine-sensitive aspartokinase 3 | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 101 a.a. Molecular weight: 11284.02 Da Isoelectric Point: 9.9325
>T217408 WP_033144376.1 NZ_CP083815:c251778-251476 [Enterobacter asburiae]
MKEIVQTESFQRWEQNLKDRRAKTIIASRLFRLANGLAGDIKPVGEGISELRIHYGPGYRIYFKDQGNCIIVLLCGGDKS
SQARDILMAKMLSNPNGRSE
MKEIVQTESFQRWEQNLKDRRAKTIIASRLFRLANGLAGDIKPVGEGISELRIHYGPGYRIYFKDQGNCIIVLLCGGDKS
SQARDILMAKMLSNPNGRSE
Download Length: 303 bp
>T217408 NZ_CP114278:2915669-2915986 [Brevundimonas vesicularis]
GTGAGCGCCAGATATTCCAATGCTGCGAAACGCGATCTGATTGCCATCTATCTTGATGGTGCGGCGAAGTTTGGATCGCG
GCAAGCTGCAGCCTACACAACAGGTCTCGGCGCCACCGTCCGAATGATCAGCGACTACCCTCTTTCGTCTCGCCTCAGGA
CCGAGCTCGATCTGCCGGTCCGCGTGCGAACCTACAAAGCTCACGTCATTATCTACGTGATAGAAGAAGGTGGGGTGTTG
GTGCTTCGGTTTCGTCACGGGCACGAAGATTGGCAGTCAGATCCACTCGGTGGTGACTTGGACAAGGATAAACCATGA
GTGAGCGCCAGATATTCCAATGCTGCGAAACGCGATCTGATTGCCATCTATCTTGATGGTGCGGCGAAGTTTGGATCGCG
GCAAGCTGCAGCCTACACAACAGGTCTCGGCGCCACCGTCCGAATGATCAGCGACTACCCTCTTTCGTCTCGCCTCAGGA
CCGAGCTCGATCTGCCGGTCCGCGTGCGAACCTACAAAGCTCACGTCATTATCTACGTGATAGAAGAAGGTGGGGTGTTG
GTGCTTCGGTTTCGTCACGGGCACGAAGATTGGCAGTCAGATCCACTCGGTGGTGACTTGGACAAGGATAAACCATGA
Antitoxin
Download Length: 96 a.a. Molecular weight: 10111.59 Da Isoelectric Point: 6.4596
>AT217408 WP_033144375.1 NZ_CP083815:c251473-251186 [Enterobacter asburiae]
MHKLTPYDPANALVDDEEIAVFMADALETGDSAYIAKALGVIARAKGMSTISQQTGLSREQLYRSFSDKGNPTLKTTLAV
MKALGLGLTIKHAGD
MHKLTPYDPANALVDDEEIAVFMADALETGDSAYIAKALGVIARAKGMSTISQQTGLSREQLYRSFSDKGNPTLKTTLAV
MKALGLGLTIKHAGD
Download Length: 288 bp
>AT217408 NZ_CP114278:2915404-2915661 [Brevundimonas vesicularis]
ATGGCGACGATGAACATCTCCCTGCCCGATCCGATGAAGGCCTGGGTCGAGGAACAGGCGAAATCCGGGCGCTACGCCAA
CACGTCCGACGTGGTGCGCGATCTGATCCGCCGCGAGCAGGTCAAGGCCGAGAAGATCGCCCACTGGAACACTCTGATCG
AAGAGGCCTACGCCTCCGGGATCAGCGAAATGACGTTCGAGGAGATTATCGGTGAGGCCCGCGCGGAAGCGCAGGCTCGG
GCTTCTCGCGCAGCGTAG
ATGGCGACGATGAACATCTCCCTGCCCGATCCGATGAAGGCCTGGGTCGAGGAACAGGCGAAATCCGGGCGCTACGCCAA
CACGTCCGACGTGGTGCGCGATCTGATCCGCCGCGAGCAGGTCAAGGCCGAGAAGATCGCCCACTGGAACACTCTGATCG
AAGAGGCCTACGCCTCCGGGATCAGCGAAATGACGTTCGAGGAGATTATCGGTGAGGCCCGCGCGGAAGCGCAGGCTCGG
GCTTCTCGCGCAGCGTAG
Structures
Toxin
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Source | ID | Structure |
---|---|---|
No matching records found |
Antitoxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A808IFF3 |