Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 251186..251778 Replicon chromosome
Accession NZ_CP083815
Organism Enterobacter asburiae strain 161373-yvys

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag LCD39_RS01135 Protein ID WP_033144376.1
Coordinates 251476..251778 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID A0A808IFF3
Locus tag LCD39_RS01130 Protein ID WP_033144375.1
Coordinates 251186..251473 (-) Length 96 a.a.

Genomic Context


LCD39_RS01125LCD39_RS01140LCD39_RS01130LCD39_RS01135LCD39_RS01145LCD39_RS01150LCD39_RS01155
Location: 249558..251189 (1632 bp)
Type: Others
Protein ID: WP_033144374.1
Location: 251976..252848 (873 bp)
Type: Others
Protein ID: WP_023309993.1
Location: 251186..251473 (288 bp)
Type: Antitoxin
Protein ID: WP_033144375.1
Location: 251476..251778 (303 bp)
Type: Toxin
Protein ID: WP_033144376.1
Location: 252849..253121 (273 bp)
Type: Others
Protein ID: WP_023309994.1
Location: 253172..254116 (945 bp)
Type: Others
Protein ID: WP_048977786.1
Location: 254210..255559 (1350 bp)
Type: Others
Protein ID: WP_246946881.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
LCD39_RS01125 (LCD39_01125)249558..251189+1632WP_033144374.1Na/Pi cotransporter family protein-
LCD39_RS01130 (LCD39_01130)251186..251473-288WP_033144375.1putative addiction module antidote proteinAntitoxin
LCD39_RS01135 (LCD39_01135)251476..251778-303WP_033144376.1type II toxin-antitoxin system RelE/ParE family toxinToxin
LCD39_RS01140 (LCD39_01140)251976..252848+873WP_023309993.123S rRNA pseudouridine(2604) synthase RluF-
LCD39_RS01145 (LCD39_01145)252849..253121-273WP_023309994.1DUF3811 domain-containing protein-
LCD39_RS01150 (LCD39_01150)253172..254116-945WP_048977786.1ketopantoate/pantoate/pantothenate transporter PanS-
LCD39_RS01155 (LCD39_01155)254210..255559-1350WP_246946881.1lysine-sensitive aspartokinase 3-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 101 a.a.        Molecular weight: 11284.02 Da        Isoelectric Point: 9.9325

>T217408 WP_033144376.1 NZ_CP083815:c251778-251476 [Enterobacter asburiae]
MKEIVQTESFQRWEQNLKDRRAKTIIASRLFRLANGLAGDIKPVGEGISELRIHYGPGYRIYFKDQGNCIIVLLCGGDKS
SQARDILMAKMLSNPNGRSE

Download         Length: 303 bp

>T217408 NZ_CP114278:2915669-2915986 [Brevundimonas vesicularis]
GTGAGCGCCAGATATTCCAATGCTGCGAAACGCGATCTGATTGCCATCTATCTTGATGGTGCGGCGAAGTTTGGATCGCG
GCAAGCTGCAGCCTACACAACAGGTCTCGGCGCCACCGTCCGAATGATCAGCGACTACCCTCTTTCGTCTCGCCTCAGGA
CCGAGCTCGATCTGCCGGTCCGCGTGCGAACCTACAAAGCTCACGTCATTATCTACGTGATAGAAGAAGGTGGGGTGTTG
GTGCTTCGGTTTCGTCACGGGCACGAAGATTGGCAGTCAGATCCACTCGGTGGTGACTTGGACAAGGATAAACCATGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10111.59 Da        Isoelectric Point: 6.4596

>AT217408 WP_033144375.1 NZ_CP083815:c251473-251186 [Enterobacter asburiae]
MHKLTPYDPANALVDDEEIAVFMADALETGDSAYIAKALGVIARAKGMSTISQQTGLSREQLYRSFSDKGNPTLKTTLAV
MKALGLGLTIKHAGD

Download         Length: 288 bp

>AT217408 NZ_CP114278:2915404-2915661 [Brevundimonas vesicularis]
ATGGCGACGATGAACATCTCCCTGCCCGATCCGATGAAGGCCTGGGTCGAGGAACAGGCGAAATCCGGGCGCTACGCCAA
CACGTCCGACGTGGTGCGCGATCTGATCCGCCGCGAGCAGGTCAAGGCCGAGAAGATCGCCCACTGGAACACTCTGATCG
AAGAGGCCTACGCCTCCGGGATCAGCGAAATGACGTTCGAGGAGATTATCGGTGAGGCCCGCGCGGAAGCGCAGGCTCGG
GCTTCTCGCGCAGCGTAG

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
AlphaFold DBA0A808IFF3

References