Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/RHH(antitoxin)
Location 4082535..4083097 Replicon chromosome
Accession NZ_CP083809
Organism Pantoea agglomerans strain 33.1

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag LB453_RS22120 Protein ID WP_103797101.1
Coordinates 4082535..4082828 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LB453_RS22125 Protein ID WP_103797102.1
Coordinates 4082816..4083097 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LB453_RS22100 (LB453_22035) 4078603..4079268 - 666 WP_103797097.1 6-phosphogluconate phosphatase -
LB453_RS22105 (LB453_22040) 4079418..4080731 + 1314 WP_103797098.1 NCS2 family permease -
LB453_RS22110 (LB453_22045) 4080848..4081597 - 750 WP_103797099.1 4'-phosphopantetheinyl transferase superfamily protein -
LB453_RS22115 (LB453_22050) 4081764..4082354 - 591 WP_103797100.1 malonic semialdehyde reductase -
LB453_RS22120 (LB453_22055) 4082535..4082828 - 294 WP_103797101.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LB453_RS22125 (LB453_22060) 4082816..4083097 - 282 WP_103797102.1 CopG family ribbon-helix-helix protein Antitoxin
LB453_RS22130 (LB453_22065) 4083196..4084560 - 1365 WP_084884316.1 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE -
LB453_RS22135 (LB453_22070) 4084643..4086289 - 1647 WP_224481581.1 membrane protein insertase YidC -
LB453_RS22140 (LB453_22075) 4086292..4086550 - 259 Protein_3819 membrane protein insertion efficiency factor YidD -
LB453_RS22145 (LB453_22080) 4086514..4086873 - 360 WP_033755442.1 ribonuclease P protein component -
LB453_RS22150 (LB453_22085) 4086889..4087029 - 141 WP_003849659.1 50S ribosomal protein L34 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-95)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11165.85 Da        Isoelectric Point: 8.0139

>T217405 WP_103797101.1 NZ_CP083809:c4082828-4082535 [Pantoea agglomerans]
MPQVIVTQRAASGLARCREFLMNKNPLAALKAGQVLEKQFEQLEKNPEIGRPFVEAPQLRELLIGFGDSGYVALYRYEQH
EDRIYILAFRHQKEAGY

Download         Length: 294 bp

>T217405 NZ_CP114277:1237178-1237321 [Rickettsia rickettsii]
ATGAGAGATCATGCCCTTATAGGTAATTGGAAAGATTGTAGAGATTGTCATATTAAAGCGGATTTAGTATTAATTTATAG
AAAACCCGATGCTGACACATTGGAGTTAATACAATTAGGTTCAAACAGTACACTTGGTTTTTAA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10910.22 Da        Isoelectric Point: 5.2246

>AT217405 WP_103797102.1 NZ_CP083809:c4083097-4082816 [Pantoea agglomerans]
MPTTSTTLKIDSLLKERVKKLADSRDRSPHYLMVTAIAQYIEREEARESFKQEALDSWREYQETGLHLTGEEVKSWLRNW
GTEAETDIPECHK

Download         Length: 282 bp

>AT217405 NZ_CP114277:1236823-1237086 [Rickettsia rickettsii]
ATGTCTGCTGATTCTATTGTGCGAGCCCGTATTAATGAAGACGTGAAAGAAGAAGCAGCTTTAGTGCTTGCTGCTATGGG
ACTTACTTTATCTGATGCTGTTCGTATGCTGTTATTTCGTGTTGCTCGTGAAAAAGCATTGCCGTTTGAACCACTTATCC
CAAATGATGAAACAATTAAAGCTATGAAAGCTGCAAGAAGCGGCAAATTAGTTCATGTTGGTAATATCAATAATTTGTTA
TCTGATTTAAATGAGAACGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References