Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-MazE
Location 3527526..3528115 Replicon chromosome
Accession NZ_CP083809
Organism Pantoea agglomerans strain 33.1

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag LB453_RS19545 Protein ID WP_103793814.1
Coordinates 3527783..3528115 (+) Length 111 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag LB453_RS19540 Protein ID WP_103793815.1
Coordinates 3527526..3527783 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LB453_RS19530 (LB453_19470) 3524072..3524530 + 459 WP_033749344.1 DNA polymerase III subunit chi -
LB453_RS19535 (LB453_19475) 3524536..3527391 + 2856 WP_103793816.1 valine--tRNA ligase -
LB453_RS19540 (LB453_19480) 3527526..3527783 + 258 WP_103793815.1 antitoxin Antitoxin
LB453_RS19545 (LB453_19485) 3527783..3528115 + 333 WP_103793814.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
LB453_RS19550 (LB453_19490) 3528133..3528645 - 513 WP_224481555.1 hypothetical protein -
LB453_RS19555 (LB453_19495) 3528934..3529437 + 504 WP_103793812.1 GNAT family N-acetyltransferase -
LB453_RS19560 (LB453_19500) 3529432..3530220 - 789 WP_103793811.1 histidine phosphatase family protein -
LB453_RS19565 (LB453_19505) 3530845..3531606 - 762 WP_103793810.1 tRNA isopentenyl-2-thiomethyl-A-37 hydroxylase MiaE -
LB453_RS19570 (LB453_19510) 3531664..3532092 - 429 WP_033793365.1 ribonuclease E inhibitor RraB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-109)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 11919.81 Da        Isoelectric Point: 9.4897

>T217404 WP_103793814.1 NZ_CP083809:3527783-3528115 [Pantoea agglomerans]
MERGEIWLVSLDPTAGHEQQGTRPVLIVSPAAFNQLTQTPVVLPITTGGSFARTAGFAVSLDEAGTRTRGVIRCDQPRAI
DMRARQGKRLEKIPADVMAEVQAILRAILI

Download         Length: 333 bp

>T217404 NZ_CP114268:4801-5088 [Acinetobacter sp. TR3]
ATGGAACTGTATTTCGAATGGGATGAGGCAAAGAACCAAAAGAATCAGAAAAAACATGATGTATCTTTTGAAACTGCAAG
CCTCATTTTTGAAGATCCTTTAAGGATCTCAATCCAAGATAGACATACTGGTGGTGAAGAACGTTGGCAAACCATCGGTA
TGGTTAAAGGCGTACTAATGCTCTTAGTTGCTCACACCATCTTTGATGAAGATGACTGTGAAATCATACGAATCATTAGT
GCAAGGGAAGTCACCAAAGCAGAGCGAGATAAATATGAGCATGGTTAG

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9215.61 Da        Isoelectric Point: 4.5007

>AT217404 WP_103793815.1 NZ_CP083809:3527526-3527783 [Pantoea agglomerans]
MHTTHLRKVGGSVMLAVPPALLDILQLSADAQVGLTVDNGRLIIEPKPVPSYTLSELLAKCDPNAELTDEDRQWLNATPV
GKEEL

Download         Length: 258 bp

>AT217404 NZ_CP114268:5075-5386 [Acinetobacter sp. TR3]
ATGAGCATGGTTAGATATACACGCAAAGAACTGAATGAAAATTTCAGTGACAAGCAAGATGCTGAAATTAAACGCTTGCT
TGCTAAGGGTACTGTGTCAGATGATCAATTAGATTTGTCTGATATTCCTGAAATTACGGACTGGAGTAATGCTATTCGTC
ATGGACAATTTTATCGTCCAGTGAAGCAACAGACTTCTATTCGATTAGATGCTGATGTTCTTGCATGGTTTAAAGCACAA
GGCAAGGGTTATCAGACACGCATGAATAACATTCTGCGTGAAGCAATGTTAAAAGATTTAAAAAATCATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References