Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09907-MazE
Location 150820..151394 Replicon chromosome
Accession NZ_CP083809
Organism Pantoea agglomerans strain 33.1

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag LB453_RS03130 Protein ID WP_199187331.1
Coordinates 150820..151149 (-) Length 110 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag LB453_RS03135 Protein ID WP_103796256.1
Coordinates 151143..151394 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LB453_RS03110 (LB453_03095) 146177..147097 + 921 WP_103796251.1 AraC family transcriptional regulator -
LB453_RS03115 (LB453_03100) 147171..148298 + 1128 WP_103796252.1 GNAT family N-acetyltransferase -
LB453_RS03120 (LB453_03105) 148292..150124 - 1833 WP_103796253.1 ABC transporter ATP-binding protein -
LB453_RS03125 (LB453_03110) 150188..150694 + 507 WP_103796254.1 GNAT family N-acetyltransferase -
LB453_RS03130 (LB453_03115) 150820..151149 - 330 WP_199187331.1 endoribonuclease MazF Toxin
LB453_RS03135 (LB453_03120) 151143..151394 - 252 WP_103796256.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
LB453_RS03140 151503..151721 - 219 WP_103796257.1 hypothetical protein -
LB453_RS03145 (LB453_03125) 151872..153263 + 1392 WP_103796258.1 MFS transporter -
LB453_RS03150 (LB453_03130) 153355..154518 + 1164 WP_103796259.1 HD-GYP domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(6-102)

Antitoxin

SpoVT-AbrB domain

(6-52)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 11819.98 Da        Isoelectric Point: 10.4737

>T217392 WP_199187331.1 NZ_CP083809:c151149-150820 [Pantoea agglomerans]
MVMPFVPDAGDILWLDFTPHAGHKQAGRRPALVMSPAMYNRIGMMICVPLTTKIKGNPFEVPIAGAPANVALADQVRNLD
WKARNAAPKGKATADELEAVRKLTRMLVG

Download         Length: 330 bp

>T217392 NZ_CP114201:3263577-3263987 [Delftia acidovorans]
ATGATGCTGTACATGCTGGACACCAATGCCGCCAGCGAAGCCATCCGGGGCAATCCCTTGTTTGATGCGCGCTTGCAAGC
CCTCGCACCAGGGCAGTGGTGCGTAGGTGCAGTGACCTGTTCCGAGCTGCGCTATGGAATTGCCCGGCGGCCCGAGGCGG
TACGGCTGGCACGGATCGTGGAGGCGTTCCTGCACATCACCGCCATCCTGCCCTGGGACGCCAGGGCGGCCAACCAGCAT
GGTCAGCTGCGTGCTTATCTGCGTGCCCAGGGTTCGCCGATTGGAGACTTCGACGAAATGATCGCCGCACATGCGCTGGC
CCTGGACGCGATCCTGGTCACAGACAATGTGCGGCATTTCGAACGCATTCCCGGGCTCAGGATCGAAAACTGGCTGCGCC
AGGGGCATTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9513.89 Da        Isoelectric Point: 4.3444

>AT217392 WP_103796256.1 NZ_CP083809:c151394-151143 [Pantoea agglomerans]
MRQTIKRWGNSPAVRIPAHMMTLMNMDIDAEVEISVQTDANNMQRLVIEPVRQVTLETIMSQVTPENMHGEMDFGDAQGQ
EIW

Download         Length: 252 bp

>AT217392 NZ_CP114201:3263314-3263580 [Delftia acidovorans]
ATGCCACCCGTTACCGCCCAACTTTTCGCCACTGATGGCGTTCAAGCCGTAAAGCTGCCTGCCGAGTTTCGCTTCGAAGA
TCGAGCCGAGGTGTATATCCGCCGCGATGAAAACACCGGAGACGTCATTCTTTCGACCATTCCTCGCGCGGACTGGAGTG
AATTCATGCGGCTGCGCCACCAGCTGGGGCATGCGGCCGAGTCGGCCCTCCCCGTGCGCCAACAGAGCAGCGAGCAACGC
GATCCCTTCCAAGGGTGGGAGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References