Detailed information of TA system TA217379

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YoeB-YefM
• Location: 3280770..3281275
• Replicon: chromosome
• Accession: NZ_CP083804
• Organism: Xanthomonas translucens pv. pistacia strain ICMP 16317

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: K8O61_RS14315
• Protein ID: WP_237654959.1
• Coordinates: 3281018..3281275 (+)
• Length: 86 a.a.

Antitoxin (Protein)

• Gene name: relE
• Uniprot ID: A0A1C3TRJ9
• Locus tag: K8O61_RS14310
• Protein ID: WP_003468816.1
• Coordinates: 3280770..3281021 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
K8O61_RS14285 (K8O61_14290)	3275790..3278240	+	2451	WP_237654956.1	DEAD/DEAH box helicase family protein	-
K8O61_RS14290 (K8O61_14295)	3278395..3278517	-	123	WP_235426527.1	hypothetical protein	-
K8O61_RS14295 (K8O61_14300)	3278566..3279009	-	444	WP_039007331.1	nuclear transport factor 2 family protein	-
K8O61_RS14300 (K8O61_14305)	3279130..3279852	+	723	WP_237654957.1	helix-turn-helix transcriptional regulator	-
K8O61_RS14305 (K8O61_14310)	3279849..3280613	-	765	WP_237654958.1	DNA-formamidopyrimidine glycosylase family protein	-
K8O61_RS14310 (K8O61_14315)	3280770..3281021	+	252	WP_003468816.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
K8O61_RS14315 (K8O61_14320)	3281018..3281275	+	258	WP_237654959.1	Txe/YoeB family addiction module toxin	Toxin
K8O61_RS14325 (K8O61_14330)	3281908..3282261	-	354	WP_039007341.1	PilZ domain-containing protein	-
K8O61_RS14330 (K8O61_14335)	3282258..3283235	-	978	WP_058196366.1	DNA polymerase III subunit delta'	-
K8O61_RS14335 (K8O61_14340)	3283232..3283900	-	669	WP_058196365.1	dTMP kinase	-
K8O61_RS14340 (K8O61_14345)	3283897..3284964	-	1068	WP_237654960.1	endolytic transglycosylase MltG	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (2-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-74)

Sequences

Toxin

Protein

• Length: 86 a.a.
• Molecular weight: 10083.52 Da
• Isoelectric Point: 9.3759

>T217379 WP_237654959.1 NZ_CP083804:3281018-3281275 [Xanthomonas translucens pv. pistacia]
VTLQFSDNAWEDDLYWQQTDKKMLKRVNDLIKAIQRDPFQGVGKPEPLRHALAGYWSRRINDEHRIVYKVEAGVLLIAQV
RYHYA

Nucleotide

• Length: 258 bp

>T217379 NZ_CP114186:c1528602-1528312 [Vibrio parahaemolyticus]
ATGACCTATAAACTCGACTTTAAAAAGAGCGCCCTCAAAGAGTGGAAAAAGCTTGGTTCTACTCTGCAACAACAATTTAA
GAAAAAGCTAATCGAGCGCTTAGATAACCCACATGTTCCGGCTTCAAAACTTTCTGGAGCTGACAACATGTATAAAATTA
AGTTGCGTCAATCGGGCTACCGCCTCGTCTACAAAGTTGAAGACGATGTCATCATTGTAACCGTCTTAGCAGTCGGAAAA
CGCGAACGTAGCGATGTTTACCGTAAAGCAATGAAAAGGTTAGATGATTGA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9281.56 Da
• Isoelectric Point: 5.1186

>AT217379 WP_003468816.1 NZ_CP083804:3280770-3281021 [Xanthomonas translucens pv. pistacia]
MDTITYSAARAALADTMERVVNNHEPVIITRSREQSVVMLSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKARD
LAE

Nucleotide

• Length: 252 bp

>AT217379 NZ_CP114186:c1528840-1528592 [Vibrio parahaemolyticus]
ATGACCACTAGAATTTTAGCCGATGTTGCTGCAAGCATTACTGAGTTGAAAGCTAACCCTATGAAAGTTGCAACTAGTGC
TTACGGCGAACCTGTTGCTGTATTAAACCGAAATGAGCCAGCATTCTATTGCGTACCTGCCGAAGCGTACGAAATGATGA
TGGACAGACTCGAAGATCTTGAACTACTAGCTATCGCTAAAGAACGTGAATCTGAAGAGAGCATTTCGGTAAATATTGAT
GACCTATAA

Structures

Antitoxin

• AlphaFold DB: A0A1C3TRJ9