217378

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 280659..281044 Replicon chromosome
Accession NZ_CP083804
Organism Xanthomonas translucens pv. pistacia strain ICMP 16317

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0K2ZHE5
Locus tag K8O61_RS01195 Protein ID WP_003469322.1
Coordinates 280910..281044 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A514EHQ9
Locus tag K8O61_RS01190 Protein ID WP_039006387.1
Coordinates 280659..280811 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K8O61_RS01160 (K8O61_01175) 276164..276436 - 273 WP_176717140.1 hypothetical protein -
K8O61_RS01165 (K8O61_01180) 276598..277569 + 972 WP_237655402.1 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA -
K8O61_RS01170 (K8O61_01185) 277566..278306 + 741 WP_039006389.1 type III pantothenate kinase -
K8O61_RS01175 (K8O61_01190) 278316..279170 + 855 WP_068830182.1 SPOR domain-containing protein -
K8O61_RS01185 (K8O61_01200) 279591..280514 + 924 WP_039006388.1 arginase -
K8O61_RS01190 (K8O61_01205) 280659..280811 + 153 WP_039006387.1 entericidin A/B family lipoprotein Antitoxin
K8O61_RS01195 (K8O61_01210) 280910..281044 + 135 WP_003469322.1 entericidin A/B family lipoprotein Toxin
K8O61_RS01200 (K8O61_01215) 281244..281459 + 216 WP_009574162.1 CsbD family protein -
K8O61_RS01205 (K8O61_01220) 281529..282371 - 843 WP_080763519.1 hypothetical protein -
K8O61_RS01210 (K8O61_01225) 282482..283792 + 1311 WP_039006381.1 tryptophan--tRNA ligase -
K8O61_RS01215 (K8O61_01230) 284075..284998 + 924 WP_058195883.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4604.40 Da        Isoelectric Point: 9.2977

>T217378 WP_003469322.1 NZ_CP083804:280910-281044 [Xanthomonas translucens pv. pistacia]
MKRTFAWMLLAMFSVGLLSGCNTVAGAGKDVKSAGEKVEDAAKN

Download         Length: 135 bp

>T217378 NZ_CP114186:c1519493-1519197 [Vibrio parahaemolyticus]
ATGCAAAAGAATAAATACAAACTAAGTAAATTAGCTCAGGCTCATTTATTAAAAATCAAAAACTACACCGTTAATAACTT
TTCAGAGATGCAGTGGCGCAATTACAAAGATACGTTACTAACTGGGTTTCAGATGCTTGCTGACAATCCGGAAGTTGGTA
GAAGTTGCGATGACATTTACCCAAACGGGTTTCACTTTCCTGTTGGTAAGCACACAGCTTACTTTACAAAAGAAGACGGC
TTCATTTTGGTTGTAGCTGTACTCGGTCAGTCACAATTACCGCAAAACCACTTATGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5363.35 Da        Isoelectric Point: 8.1210

>AT217378 WP_039006387.1 NZ_CP083804:280659-280811 [Xanthomonas translucens pv. pistacia]
MKRLFTLTMLTLFCAGMLTGCNTMAGAGKDMQKAGDKVENKADDCKDGKC

Download         Length: 153 bp

>AT217378 NZ_CP114186:c1519742-1519500 [Vibrio parahaemolyticus]
ATGCACACATTAACAGCAAATGATGCGAAACGTAATTTTGGTGAACTTCTTCTGAGTGCCCAACGTGAGCCAGTAAAAAT
TAGCAAAAACAGTAAAGACGCCGTAGTTGTAATGTCTATTAAAGATTATGAAGAGCTAGAAGCTATGAAAGCTGATTACC
TTAAACATTGCTTTGAATCCGCGAAAAAAGACCTAGCGCAAGGCAATGTGGTTGATGGTGAAGACTTCTTGAGCGCCTTG
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K2ZHE5

Antitoxin

Source ID Structure
AlphaFold DB A0A514EHQ9

References