Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1945352..1945496 Replicon chromosome
Accession NZ_CP083790
Organism Klebsiella variicola strain INF352

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1945388..1945490 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1945352..1945496 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LB484_RS09525 (LB484_09525) 1940481..1942541 + 2061 WP_008804266.1 oligopeptidase B -
LB484_RS09530 (LB484_09530) 1942545..1943204 - 660 WP_008804267.1 exodeoxyribonuclease X -
LB484_RS09535 (LB484_09535) 1943283..1943513 - 231 WP_012541260.1 DNA polymerase III subunit theta -
LB484_RS09540 (LB484_09540) 1943627..1944001 + 375 WP_023340401.1 CopC domain-containing protein YobA -
LB484_RS09545 (LB484_09545) 1944005..1944874 + 870 WP_012541262.1 copper homeostasis membrane protein CopD -
LB484_RS09550 (LB484_09550) 1944891..1945229 + 339 WP_008804271.1 YebY family protein -
- 1945352..1945496 - 145 - - Antitoxin
- 1945388..1945490 + 103 - - Toxin
LB484_RS09555 (LB484_09555) 1945875..1946018 - 144 WP_048268691.1 Ecr family regulatory small membrane protein -
LB484_RS09560 (LB484_09560) 1946122..1947090 - 969 WP_162493241.1 VirK/YbjX family protein -
LB484_RS09565 (LB484_09565) 1947247..1947900 + 654 WP_022066249.1 protein-serine/threonine phosphatase -
LB484_RS09570 (LB484_09570) 1947897..1948088 - 192 WP_002911395.1 YebW family protein -
LB484_RS09575 (LB484_09575) 1948186..1948425 - 240 WP_002911393.1 YebV family protein -
LB484_RS09580 (LB484_09580) 1948541..1949974 - 1434 WP_012967754.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T217341 NZ_CP083790:1945388-1945490 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT217341 NZ_CP083790:c1945496-1945352 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References