217260

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yfjZ-ypjF/CbtA-CbeA
Location 4541954..4542660 Replicon chromosome
Accession NZ_CP083754
Organism Serratia marcescens strain YL4

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag LBP97_RS21430 Protein ID WP_039556156.1
Coordinates 4542292..4542660 (+) Length 123 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag LBP97_RS21425 Protein ID WP_039556157.1
Coordinates 4541954..4542271 (+) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LBP97_RS21380 (LBP97_21415) 4537095..4537919 + 825 WP_238968998.1 DUF932 domain-containing protein -
LBP97_RS21385 (LBP97_21420) 4538128..4538838 + 711 WP_221914198.1 DeoR family transcriptional regulator -
LBP97_RS21390 (LBP97_21425) 4538864..4539400 + 537 WP_221914197.1 DUF4339 domain-containing protein -
LBP97_RS21395 (LBP97_21430) 4539442..4539879 + 438 WP_221914195.1 hypothetical protein -
LBP97_RS21400 (LBP97_21435) 4539946..4540356 + 411 WP_221914193.1 hypothetical protein -
LBP97_RS21405 (LBP97_21440) 4540434..4540670 + 237 WP_221914192.1 DUF905 domain-containing protein -
LBP97_RS21410 (LBP97_21445) 4540756..4541214 + 459 WP_238969000.1 antirestriction protein -
LBP97_RS21415 (LBP97_21450) 4541223..4541705 + 483 WP_238969002.1 DNA repair protein RadC -
LBP97_RS21420 (LBP97_21455) 4541714..4541887 + 174 WP_238969004.1 DUF987 family protein -
LBP97_RS21425 (LBP97_21460) 4541954..4542271 + 318 WP_039556157.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
LBP97_RS21430 (LBP97_21465) 4542292..4542660 + 369 WP_039556156.1 TA system toxin CbtA family protein Toxin
LBP97_RS21435 (LBP97_21470) 4543049..4543267 + 219 WP_015376761.1 TM2 domain-containing protein -
LBP97_RS21440 (LBP97_21475) 4543319..4543852 - 534 WP_043135545.1 hypothetical protein -
LBP97_RS21445 (LBP97_21480) 4544339..4545454 + 1116 WP_238969006.1 hypothetical protein -
LBP97_RS21450 (LBP97_21485) 4545458..4546162 - 705 WP_164099586.1 hypothetical protein -
LBP97_RS21455 (LBP97_21490) 4546179..4547354 - 1176 WP_164099585.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-111)

Antitoxin

Antitoxin CbeA

(5-104)


Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13715.99 Da        Isoelectric Point: 8.7174

>T217260 WP_039556156.1 NZ_CP083754:4542292-4542660 [Serratia marcescens]
MKTLPATISRATKPCLSPVAVWQMLLTRLLEQHYGLMLSDTPFSDETIIKEHIDAGITLANAVNFLVEKYELVRIDRNGF
TSQVQAPYLTATDILQARKACGLMSRCSYREVSNIVLSRSRL

Download         Length: 369 bp

>T217260 NZ_CP114128:1062845-1063156 [Escherichia coli]
ATGCACATCATTTCTAAAGTGCCATTTGAAGAGTCTGCGCGTAAATATCCTAACGACGCTCTGGCTCTTCAGGCATTGTA
TCGGGTTATTAAGGAAACGGATTTTTCTACGCCAGAAGAAATGCGAACGGCGTTTCCCAACCTCGACAATTTTAAATATC
GCAACAAATGGTACGTTCTGGATGTCGGCGGGAACAATCTTAGGGTTATTGCCTACATAAACTTTGTTAATAAGCGGTTC
TTTGTGAAGCACATAACGAATCACGCAGAGTATGACAAACTGACACGTTACTACAGAGAGAACAAAGAATGA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11901.43 Da        Isoelectric Point: 6.6246

>AT217260 WP_039556157.1 NZ_CP083754:4541954-4542271 [Serratia marcescens]
MSNITWGLQRDTTPRLGARLVQEGNQLHYLADRASITGKFSDAECRKLDETFPHFISQMESMLTTGEMNPRHAHCVILYH
NGFTCEADTLGSCGYVYISVYPTQR

Download         Length: 318 bp

>AT217260 NZ_CP114128:1063153-1063572 [Escherichia coli]
ATGACTGCTAATGCTGCACGCGCTGTTAAAGCAACAAGAGAACTGGTCAATGCAGTCCCCTTTCTGGGAGGCAGTGACTC
AGAAGATGATTATCGTGAAGCACTGGAACTGGTCGAATATTTGATTGAAGAAGATGACACCAATCCACTTATCGACTTTC
TGGCGAGCCGCATTGCAGAGTATGAAAACAACAACGAAAAGTTTGCAGAGTTCGACAAAGCCGTTGCGGCAATGCCGGTT
GGCGTGGCGTTACTTCGCACGTTGATTGATCAACATAATCTGACCTATGCGGATTTGAAGAACGAAATCGGCTCTAAATC
CCTGGTTAGTCAGATTTTGTCTGGACAACGATCCCTGACAATATCCCACATTAAGGCACTTTCAGCCCGATTTGGCGTTA
AGCCGGAATGGTTTCTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References