Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 767612..768131 Replicon chromosome
Accession NZ_CP083746
Organism Pseudomonas sp. p1(2021b)

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag K8374_RS03605 Protein ID WP_224457955.1
Coordinates 767612..767902 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag K8374_RS03610 Protein ID WP_224457956.1
Coordinates 767892..768131 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K8374_RS03580 (K8374_03580) 763023..763622 + 600 WP_224457951.1 tail assembly protein -
K8374_RS03585 (K8374_03585) 763619..764074 + 456 WP_224457952.1 hypothetical protein -
K8374_RS03590 (K8374_03590) 764312..764488 + 177 WP_224457953.1 hypothetical protein -
K8374_RS03595 (K8374_03595) 764656..765276 + 621 WP_224457954.1 hypothetical protein -
K8374_RS03600 (K8374_03600) 766981..767184 + 204 WP_169898427.1 hypothetical protein -
K8374_RS03605 (K8374_03605) 767612..767902 - 291 WP_224457955.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
K8374_RS03610 (K8374_03610) 767892..768131 - 240 WP_224457956.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
K8374_RS03615 (K8374_03615) 768713..768940 + 228 WP_224457957.1 hypothetical protein -
K8374_RS03620 (K8374_03620) 769013..770587 - 1575 WP_224457958.1 methylenetetrahydrofolate reductase C-terminal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-69)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11399.30 Da        Isoelectric Point: 10.3555

>T217214 WP_224457955.1 NZ_CP083746:c767902-767612 [Pseudomonas sp. p1(2021b)]
MTYNLEFDARALKEWQKLGDTVRQQFKKKLASVLLNPRVEANRLHSLPDCYKIKLRSSGFRLVYQVIEREVVVFVVAVNK
REREQVYRKAAERLCD

Download         Length: 291 bp

>T217214 NZ_CP114038:3152635-3153381 [Bacillus velezensis]
ATGCTTTTGTTTTTTCAGATCATGGTGTGGACGATGGCGGCCGCACTCATTTTATATGTGTACGCATCCTGGCGGTATGA
GGCAAAGGTGAAAGAAAAAATGTTTGCCATCCGTAAAACGTGGTATTTACTATTTGTACTGGGCTCCATGGTCTATTGGA
CATATGATCCTGAATCGCTCTTTGCCGCATGGAGACAATATTTGATTGTTGCCGTCTGCTTTGCCCTTATTGATGCGTTT
ATCTTTTTGAGCGCGTATATCAAAAAGCTCGCCGGCAATGAATTAGAGACGGATACGCGGGAAATTTTAGAAGAAAATAA
CGAAATGCTTCACTCCTATCTTGAAAAACTGAAAACCTATCAATATCTGTTGAAAAATGAACCGATCCATGTATATTATG
GAAGTACAGAAGCTTATGCGGAAGGCATCAGCAGACTGCTGGCCGCTTATGCCGAAAAAATGAATGTCACGGCTTCCTTG
TGCGACTATTCCGCACAATCGGATAAGGACCGCTTGACGGAGCATATGCCTGATGCGGCAGACGTTCAGTCCCGTCTTAA
CCGTAAAGACGTCTACTATGATCAAAAAGGCAGGCTTGTGCTTATTCCGTTTACAGTCCAGAACCGCCATTACGTGATCA
AACTCACGTCGGAAAACCTGTTGACGGAATTCGATTATTTGCTTTTCACATCGCTAACGAGCATTTATGATTTAATGCTG
CCAATAGAAGAGGAAGGTGACGGTTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9006.44 Da        Isoelectric Point: 4.8146

>AT217214 WP_224457956.1 NZ_CP083746:c768131-767892 [Pseudomonas sp. p1(2021b)]
MASINVRIDDDLKIRAYRELEKLGVTPSELMRQALQYVAERGQLPFKPVLLTEEDEALLATVRERIAAPQRVKVSLDDL

Download         Length: 240 bp

>AT217214 NZ_CP114038:3153382-3153552 [Bacillus velezensis]
ATGGAGCAGGCATTTCAAAACGGGCAGCCGGAACAAAGAGCGAAACCGTTCAAAATGTTTAAAAAACGTTCAATGACAAG
TATCGCAAGTTACCAGGTCAGCCCTCATACCGCCAGAATTTTCAAAGAAAACGAGCGGCTGATTGACAAGTATAAACAAA
AAAAAGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References