Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-PumB/upstrm_HI1419-dnstrm_HI1420
Location 2573816..2574457 Replicon chromosome
Accession NC_008391
Organism Burkholderia ambifaria AMMD

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag BAMB_RS27455 Protein ID WP_041491610.1
Coordinates 2574119..2574457 (-) Length 113 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag BAMB_RS27450 Protein ID WP_006750245.1
Coordinates 2573816..2574115 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BAMB_RS27425 2568962..2570251 + 1290 WP_041491608.1 Rieske 2Fe-2S domain-containing protein -
BAMB_RS27430 2570248..2570736 + 489 WP_011660415.1 aromatic-ring-hydroxylating dioxygenase subunit beta -
BAMB_RS27435 2570754..2571080 + 327 WP_006756593.1 non-heme iron oxygenase ferredoxin subunit -
BAMB_RS27440 2571070..2572290 + 1221 WP_011660416.1 FAD-dependent oxidoreductase -
BAMB_RS27445 2572478..2573764 + 1287 WP_041491609.1 DUF445 domain-containing protein -
BAMB_RS27450 2573816..2574115 - 300 WP_006750245.1 putative addiction module antidote protein Antitoxin
BAMB_RS27455 2574119..2574457 - 339 WP_041491610.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BAMB_RS27460 2574761..2576401 + 1641 WP_011660419.1 acetolactate synthase large subunit -
BAMB_RS27465 2576430..2577863 + 1434 WP_011660420.1 aldehyde dehydrogenase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(16-109)

Antitoxin

Uncharacterized protein HI1420

(5-93)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12599.61 Da        Isoelectric Point: 10.2348

>T21714 WP_041491610.1 NC_008391:c2574457-2574119 [Burkholderia ambifaria AMMD]
MVDMLPFMPYSAPAFSIRTTDVFDAWFAGLQDRVAKRRIQARIDRLSMGNPGDWKSAGSPVVEMRVDHGPGYRVYYVRRG
TIWVILLCGGDKSTQRAGIRAAHAMLARLDLE

Download         Length: 339 bp

>T21714 NC_008391:c2574457-2574119 [Burkholderia ambifaria AMMD]
ATGGTTGACATGCTGCCATTCATGCCATACAGTGCACCTGCATTCAGTATCCGGACCACCGACGTCTTCGACGCGTGGTT
TGCCGGCCTGCAGGATCGCGTCGCGAAGCGGCGCATCCAGGCGCGCATCGACCGTCTGTCGATGGGCAATCCGGGCGACT
GGAAATCCGCCGGCTCTCCCGTCGTCGAAATGCGTGTCGATCACGGGCCCGGCTATCGCGTCTACTACGTCAGGCGCGGA
ACGATATGGGTGATCCTGCTCTGCGGCGGCGACAAGTCGACGCAACGGGCGGGCATCCGCGCCGCGCACGCGATGCTCGC
GCGGCTCGACCTGGAGTGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10674.11 Da        Isoelectric Point: 6.6384

>AT21714 WP_006750245.1 NC_008391:c2574115-2573816 [Burkholderia ambifaria AMMD]
MDKIKTRPWDSAEHLKTDDDMADYFEACLQEAGDDPAFIAHALGVIARARGMSQVARDAGLSREGLYKALSHDGNPSFGT
ILKVIKALGLQLHGAKAHA

Download         Length: 300 bp

>AT21714 NC_008391:c2574115-2573816 [Burkholderia ambifaria AMMD]
ATGGACAAGATCAAGACCCGGCCGTGGGATTCGGCCGAACACCTGAAAACCGACGACGACATGGCCGACTATTTCGAGGC
CTGTCTGCAGGAAGCCGGCGACGACCCGGCCTTCATCGCGCATGCGCTCGGCGTGATCGCCCGCGCGCGCGGCATGTCGC
AGGTCGCGCGCGACGCGGGCCTGTCGCGCGAAGGGCTGTACAAGGCGCTGTCGCACGACGGCAATCCGAGCTTCGGCACG
ATCCTGAAAGTGATCAAGGCGCTCGGCCTGCAACTGCACGGCGCGAAGGCGCACGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References